52 research outputs found
The role of chromosomal proteins in the induction of a differential staining of sister chromatids by light
No full textInvolvement of sulfhydryl groups of chromosomal proteins in sister chromatid differentiation
No full textStudies on the clinical genetics of cancer
No full textThe Revolutionary progress in molecular genetics of hereditary cancer is pushing the clinical genetics of cancer into an accelerated development. For a discussion of the issues involved, it is important to clarify the vocabulary. Therefore, in Chapter 1 of this thesis a list of definitions is given for frequently used notions in the clinical genetics of cancer. ...
Zie: Summary and Future Perspectives
Lung cancer associated genes studied in vitro and in vivo using transgenic animal models
No full textThe role of chromosomal proteins in the induction of a differential staining of sister chromatids by light
No full textInvolvement of sulfhydryl groups of chromosomal proteins in sister chromatid differentiation
No full textThe mechanism of differential sister chromatid fluorescence as studied with the GC-specific DNA-ligand mithramycin
No full text
Rapid irradiation procedure for obtaining permanent differential staining of sister chromatids and aspects of its underlying mechanism
No full textApplication of molecular techniques in population genetic studies of cystic fibrosis in the Netherlands
No full textThis thesis describes the application of molecular techniques in population genetic studies of cystic fibrosis (CF), the most common serious autosomal recessive disorder affecting Caucasian populations. Birth prevalences in European countries range from 1 in 1700 to 1 in 40,000. The disease is characterized mainly by chronic obstruction and infection of the respiratory tract, meconium ileus, pancreatic insufficiency, and elevated levels of sweat electrolytes.
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