1,989 research outputs found

    The congruence subgroup property for Aut F-2: A group-theoretic proof of Asada's theorem

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    Bux K-U, Ershov MV, Rapinchuk AS. The congruence subgroup property for Aut F-2: A group-theoretic proof of Asada's theorem. Groups Geometry and Dynamics. 2011;5(2):327-353

    SHORT-TERM FLUCTUATION OF DIABETIC MACULAR EDEMA AFTER INTRAVITREAL RANIBIZUMAB INJECTION

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    Purpose: To examine the short-term fluctuation of diabetic macular edema (DME) after one intravitreal ranibizumab injection. Methods: Twenty consecutive patients with DME received an intravitreal injection of ranibizumab (0.05 mL/0.5 mg). Assessment of best-corrected visual acuity (BCVA), fundus biomicroscopy, MP-1 fundus-related perimetry using follow-up strategy (pattern macula 8 degrees 0 dB with threshold strategy 4-2), and optical coherence tomography central macular thickness (CMT), were performed at baseline and 1 hour, 24 hours, 14 days, 28 days, and 56 days after intravitreal injection of ranibizumab. Results: A total of 18 eyes of 18 patients (9 male, 9 female; mean age, 62.28 +/- 8.08 years; range, 48-75 years) who completed the 56-day follow-up were included for analysis. Intravitreal ranibizumab was found to produce significant improvements in mean BCVA and MP-1 sensitivity, as well as reduction in mean CMT, after one injection. This anatomical and functional improvement, which compared with baseline was evident as soon as the 1-hour follow-up (mean CMT reduction: t = 1.7899, P = 0.045; mean MP-1 sensitivity improvement: t = -1.9891, P = 0.0315), and lasted until the 56-day follow-up (mean BCVA improvement: t = 2.26, P < 0.05; mean CMT reduction: t = 3.61, P < 0.05; MP-1 sensitivity improvement: t = -5.21, P < 0.05). Conclusion: These short-term observations give insights into the physiopathology of DME treated with a intravitreal ranibizumab injection. RETINA 29:1274-1281, 200

    Experimental-numerical investigation on the biomimetic recovery of natural tooth structural response after porcelain veneer restoration

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    This study analyzes the effect of porcelain veneer restoration on the structural response of a maxillary incisor. Tooth deformation is evaluated, prior to and after restoration, by the synergic use of Phase-Shifting Electronic Speckle Pattern Interferometry (PS-ESPI) and 3D finite element (FE) analyses. The intact maxillary incisor and the porcelain veneer restored tooth are subject to flexural load. Displacement fields are measured with Phase-Shifting Electronic Speckle Pattern Interferometry. Experimental tests are simulated with 3D FE analyses tuning materials parameters via an optimisation-based inverse procedure. ESPI measurements indicate that the restoration design under study produced deformations very similar to those of the intact tooth under load. FE results show sharp changes in displacement and stress 1 mm above the cementenamel junction on the facial side of the restored tooth. Severe stress concentration (about 50% increase with respect to natural tooth) appears at the interface between veneer restoration and intact enamel and dentine tissues. This confirms the hypothesis that veneer restorations can amplify the effect of occlusal loading on the loss of dental hard tissue in the tooth cervical region

    State-homomorphisms on MVMV-algebras

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    summary:Riečan [12] and Chovanec [1] investigated states in MVMV-algebras. Earlier, Riečan [11] had dealt with analogous ideas in DD-posets. In the monograph of Riečan and Neubrunn [13] (Chapter 9) the notion of state is applied in the theory of probability on MVMV-algebras. We remark that a different definition of a state in an MVMV-algebra has been applied by Mundici [9], [10] (namely, the condition (iii) from Definition 1.1 above was not included in his definition of a state; in other words, only finite additivity was assumed). Below we work with the definition from [13]; but, in order to avoid terminological problems we use the term “state-homomorphism” (instead of “state”). The author is indebted to the referee for his suggestion concerning terminology. Let A\mathcal A be an MVMV-algebra which is defined on a set AA with cardA>1\mathop {\mathrm card}A>1. In the present paper we show that there exists a one-to-one correspondence between the system of all state-homomorphisms on A\mathcal A and the system of all σ\sigma -closed maximal ideals of A\mathcal A. For MVMV-algebras we apply the notation and the definitions as in Gluschankof [3]. The relations between MVMV-algebras and abelian lattice ordered groups (cf. Mundici [8]) are substantially used in the present paper

    A 60 mV Input Voltage, Process Tolerant Start-Up System for Thermoelectric Energy Harvesting

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    This paper presents a 60 mV input voltage start-up system for thermoelectric energy harvesting. A new process tolerant inverter cell is proposed, which is functional at supply voltages as low as 60 mV. Using the proposed unit cell, a ring oscillator has been implemented. The ring oscillator is followed by 40 charge-pump stages, an ultra-low-power level detector, and a boost converter. The energy harvesting system can generate an output voltage of 1 V and delivers a maximum power of 4.5 μW from a 60 mV supply. This system has been implemented in a standard 0.18 μm CMOS technology, uses neither zerothreshold voltage (normally-on) negative-channel metal-oxide semiconductor nor microelectromechanical systems switches and occupies 3.3 mm2.Accepted author manuscriptBio-Electronic

    On some properties of quasi-MV algebras and √′ quasi-MV algebras. Part II

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    The present paper is a sequel to Paoli F, Ledda A, Giuntini R, Freytes H (On some properties of QMV algebras and √′ QMV algebras, submitted). We provide two representation results for quasi-MV algebras in terms of MV algebras enriched with additional structure; we investigate the lattices of subvarieties and subquasivarieties of quasi-MV algebras; we show that quasi-MV algebras, as well as cartesian and flat √′ quasi-MV algebras, have the amalgamation property. © Springer-Verlag 2007.We gratefully acknowledge the precious information and insights we gathered from conversations or e-mail exchanges with Roberto Giuntini and Danica Jakubikova-Studenovska. We are especially indebted to Matthew Spinks for his extensive and detailed comments on a preliminary draft of the paper. The first author is partially supported by Grants MTM2004-03101 and TIN2004-07933-C03-02 from the Spanish Ministerio de Educación y Ciencia and Grant 2001SGR-00017 from the Generalitat de CatalunyaPeer Reviewe

    Measles virus causes immunogenic cell death in human melanoma

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    NoOncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma. This study demonstrates the efficacy of MV against human melanoma. It is increasingly recognised that an essential component of therapy with OV is the recruitment of host antitumour immune responses, both innate and adaptive. MV-mediated melanoma cell death is an inflammatory process, causing the release of inflammatory cytokines including type-1 interferons and the potent danger signal HMGB1. Here, using human in vitro models, we demonstrate that MV enhances innate antitumour activity, and that MV-mediated melanoma cell death is capable of stimulating a melanoma-specific adaptive immune response
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