645 research outputs found
Correspondence to Mary Ann Smith From Whitney M. Young Jr., March 21, 1960
No full textCorrespondence from Whitney M. Young Jr., Dean at the Atlanta University School of Social Work, to Mary Ann Smith discussing an upcoming documentary by Edward R. Murrow of the National Broadcasting Company. The documentary is on Atlanta, and the show's director is requesting to meet Mary Ann Smith at the dean's office. 2 pages
Thomas U. P. Charlton
No full textThomas Usher Pulanski Charlton was born in Camden, Kershaw County, South Carolina in November of 1779. His family was quite prominent among the political circles of the time. Thomas U. P.’s father was Dr. Thomas Charlton, a native of Maryland. Dr Charlton had married Lucy Kenan of North Carolina. After migrating south, Dr. Charlton join the Revolutionary Army of South Carolina in 1775.He served as a surgeon and held the rank of lieutenant. Dr. Charlton was subsequently elected to and served in the South Carolina State Legislature. He died sometime in the vicinity of 1789.https://digitalcommons.georgiasouthern.edu/sav-bios-lane/1035/thumbnail.jp
Sensory Urbanism Proceedings 2008
No full textThis book contains papers from the January 2008 conference, Sensory Urbanism, held by the University of Strathclyde, Glasgow, UK. Papers deal with issues surrounding the sensory perception of urban design and how to design better for all the senses. The book is illustrated throughout, and contains 26 papers from fields including architecture, urban design, environmental psychology, urban design, planning, sound design and more
"Asset Poverty in The United States: Its Persistence in an Expansionary Economy"
No full textFrom this paper's Preface, by Dr. Dimitri B. Papadimitriou, President: Economic growth and a rising stock market in the 1990s gave the impression that everyone was accumulating wealth and asset poverty rates were declining. The impression was supported by the official, income-based poverty measure, which exhibited a sharp decline. According to Senior Scholar Edward N. Wolff and Research Scholar Asena Caner, poverty measures should include wealth as well as income. Their study of asset poverty in the United States between 1984 and 1999 focuses on the lower end of the wealth distribution and shows that asset poverty rates did not decline during the period studied, and that the severity of poverty increased. It also shows that asset poverty is much more persistent than income poverty.
Antibody active site contributions to fluorescein ligand binding
No full textA panel of idiotypically cross-reactive murine monoclonal antibodies (Mabs) isolated in response to fluorescein (Fl) was generated and segregated based on Fl affinity. Intermediate affinity prototype Mab 9-40 (IgG1, ; K\sb{\rm a} = 3.3 10\sp7M\sp{-1}) possessed 90% active site quaternary structural homology to the intermediate affinity 9-40 idiotype family (comprised of 12-40, 3-24, 10-25, 5-14 and 5-27). The 9-40 family was 40-100% and 10-40% idiotypically related to high affinity prototype Mab 4-4-20 (IgG2a, ; K\sb{\rm a} = 1.8 10\sp{10}M\sp{-1}) and low affinity prototype Mabs 3-13 and 3-17 (K\sb{\rm a} 5.0 10\sp4M\sp{-1}), respectively. Mabs 4-4-20 and 3-13/3-17 were idiotypically distinct. This anti-Fl panel spanned a greater affinity range than any previously reported idiotype family and was exploited to define specific active site residues (and their interactions with antigen) responsible for the observed Fl binding characteristics. To begin active site structure-function assessments, V\sb{\rm H} and V\sb\kappa primary structures were obtained. Except for 5-27 and 3-13, highly homologous V\sb{\rm H}III(C) genes were utilized. D region length and sequence variabilities were seen; however, compensatory J\sb{\rm H}4 (4-4-20 and 3-24) or J\sb{\rm H}3 sequence lengths resulted in HCDR3 + FR4 to be a constant 18 amino acids. Each Mab rearranged 95% homologous V\sb\kappaII genes to J\sb\kappa1, except 10-25 (J\sb\kappa5) and 3-13 (J\sb\kappa4). In addition, 4-4-20 Fl contact residues were determined by x-ray crystallographic studies. Mabs 5-14, 9-40, 12-40 and 3-24 possessed identical Fl contact residues as 4-4-20 except for L34 His substitution for Arg. Primary structure comparisons, therefore, implicated L34 Arg responsible for increased 4-4-20 affinity. To verify this, Fl binding assays, following in vitro H and L chain reassociations, were performed. Results indicated: (1) L34 Arg was responsible for increased 4-4-20 Fl affinity; (2) L96 Trp was critical for at least an affinity of 10\sp7M\sp{-1}; and (3) Fl contact residue orientations were potentially affected by HCDR3 and/or C\sb{\rm H}1 residue differences. Recombinant 4-4-20 molecules (generated by an in vivo H chain expression system) that expressed IgG1 and IgG2b H chains possessed identical Fl binding patterns as 4-4-20 (IgG2a). This implicated HCDR3 residues for subtle binding differences observed between the various idiotype family members.Made available in DSpace on 2011-05-07T14:11:38Z (GMT). No. of bitstreams: 2
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Previous issue date: 1991Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Howard Ding ([email protected]) on 2011-05-07T15:03:59Z
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A half-century of metal and metalloid-containing polymers
No full textAlaa S. Abd-El-Aziz ... [et al.]; Includes bibliographical references and indexes.; Editor, Alaa S. Abd-El-Aziz, is currently President of the University of Prince Edward Island.Source type: Electronic(1
Title and Contents
No full textBuros-Nebraska Symposium on Measurement & Testing
Contents
Preface vii
1. Face Validity: Siren Song for Teacher-Testers 1 W. James Popham
2. Teacher Performance Assessments: A New Kind of Teacher Examination 15 Edward H. Haertel
3. Improving Teaching Through the Assessment Process 37 Donald M. Medley
4. Assessing the Quality of Teacher Assessment Tests 77 William A. Mehrens
5. Teacher Evaluation in the Organizational Context 137 Linda Darling-Hammond
6. Measuring Performance in Teacher Assessment 183 Richard J. Stiggins
7. Legal and Professional Issues in Teacher Certification Testing: A Psychometric Snark Hunt 209 George F. Madaus
8. Limitations of Using Student Achievement Data for Career Ladder Promotions and Merit Pay Decisions 261 Ronald A. Berk
9. Teaching Assessment: The Administrator\u27s Perspective 307 John R. Hoyle
10. Appraisal: The Teacher\u27s Perspective 329 Peg Shafer
11. The Assessment of Teacher Assessment: Concluding Thoughts and Some Lingering Questions 347 James V. Mitchell, Jr.
Author Index 377
Subject Index 38
Species diversity and emergence patterns of nematocerous flies (Insecta: Diptera) from three coastal salt marshes in prince Edward Island, Canada
No full textEmerging insects were monitored every 10 days between early May and late August 1993, from tidal pools in three coastal salt marshes on Prince Edward Island, Canada. The salt marsh pools ranged from about 1 m(2) to > 1,000 m(2) in surface area, and had salinities ranging from 11-27parts per thousand. Water temperatures through die study period ranged from 4-46degreesC. Most of the emerging insects were flies (Diptera; 85%), and two-thirds of these were in the sub-Order Nematocera, mainly Chironomidae, Ceratopogonidae, and Culicidae. Forty-three species of Nematocera were identified, although most of these were rare occurrences, and twelve of the species are undescribed. No consistent relationships were found between abundance or diversity and pool size or marsh for Nematocera species overall, although some species showed a statistical preference for a particular marsh or pool size. Emergence patterns were consistent between marshes for species found in different marshes, but overall patterns were highly variable, depending upon species.PT: J; CR: ADAM P, 1990, SALTMARSH ECOLOGY ALEXANDER CP, 1981, MANUAL NEARCTIC DIPT, V27, P153 ASHE P, 1990, CATALOGUE PALAEARCTI, V2, P113 BICKLEY WE, 1975, MISCELLANEOUS PUBLIC, V870 BLANDER M, 1979, ADV COLLOID INTERFAC, V10, P1 BORKENT A, COMMUNICATION BROMLEY JEC, 1979, P NOVA SCOTIA I SCI, V29, P411 BRUNDIN L, 1947, ARK ZOOL, V39, P1 CAMERON GN, 1972, ECOLOGY, V53, P58 CAMMEN LM, 1976, AM MIDL NAT, V96, P487 CAMPBELL BC, 1978, ECOLOGICAL ENTOMOLOG, V3, P181 CANNINGS RA, 1978, CAN J ZOOL, V56, P1144 COLBO MH, 1996, HYDROBIOLOGIA, V318, P117 CRANSTON PS, 1988, CAN ENTOMOL, V120, P425 CRANSTON PS, 1989, ENT SCAND S, V34, P165 DAIBER FC, 1977, WET COASTAL ECOSYSTE, P79 DAVIS LV, 1966, ECOL MONOGR, V36, P275 DOWNES JA, 1981, AGR CANADA RES BR MO, V27, P393 EPLER JH, 1987, EVOLUTIONARY MONOGR, V9, P1 EPLER JH, 1988, SPIXIANA S, V14, P105 GERRY BI, 1954, MOSQ NEWS, V14, P145 GIBERSON DJ, 1995, IMPACT BTI TREATMENT GLOOSCHENKO WA, 1988, ECOLOGICAL LAND CLAS, V24, P348 HILSENHOFF WL, 1966, ANN ENTOMOL SOC AM, V59, P465 HIRVENOJA M, 1973, ANN ZOOL FENN, V10, P1 KNEIB RT, 1984, ESTUARIES, V7, P392 LASALLE MW, 1987, ESTUARIES, V10, P303 LASALLE MW, 1991, WETLANDS, V11, P191 LONG SP, 1983, SALTMARSH ECOLOGY MENZIE CA, 1980, ESTUARIES, V3, P38 MENZIE CA, 1981, LIMNOL OCEANOGR, V26, P467 NOLTE U, 1995, CHIRONOMIDS GENES EC, P177 OLIVER DR, 1990, PUBLICATION AGR CA B, V1857 RADER DN, 1984, ESTUARIES, V7, P413 RASMUSSEN JB, 1984, HYDROBIOLOGIA, V119, P65 REIMOLD RJ, 1977, WET COASTAL ECOSYSTE, P157 REISS F, 1971, ARCH HYDROBIOL S, V40, P75 REISS F, 1980, CHIRONOMIDAE ECOLOGY, P145 REISS F, 1981, ENT SCAND S, V15, P73 REY JR, 1986, FLORIDA ENTOMOLOGIST, V60, P197 ROBERT LL, 1984, ENVIRON ENTOMOL, V13, P1097 ROBERTS BA, 1986, CAN J BOT, V64, P455 SAETHER OA, 1969, B FISH RES BD CAN, V170, P1 SAETHER OA, 1975, CAN ENTOMOL, V107, P1029 SARDA R, 1995, MAR BIOL, V121, P431 SPIES M, 1996, SPIXIANA S, V22, P61 THIENEMANN A, 1954, CHIRONOMUS LEBEN VER TIMMS BV, 1986, INT REV GES HYDROBIO, V71, P759 TUISKUNEN J, 1986, ANN ZOOL FENN, V23, P361 VERNBERG FJ, 1993, ENVIRON TOXICOL CHEM, V12, P2167 WALL WJ, 1973, ENVIRON ENTOMOL, V2, P681 WANG X, 1993, ENTOMOL SCAND, V24, P215 WARD G, 1983, CAN J ZOOL, V61, P1071 WAUGH WT, 1976, ANN ENTOMOL SOC AM, V69, P219 WELLS ED, 1988, ECOLOGICAL LAND CLAS, V24, P251 WENNER EL, 1988, ESTUARIES, V11, P29 WIRTH WW, 1994, INSECTA MUNDI, V8, P17 WOOD DM, 1979, MOSQUITOES CANADA 6; NR: 58; TC: 4; J9: ESTUARIES; PG: 13; GA: 524XJSource type: Electronic(1
The anti-fluorescein antibody active site: A single-chain site-specific mutagenesis study
No full textRestriction data tranferred 2014-07-01T11:21:50-05:00
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Reason: ETDs are only available to UIUC Users without author permissionETDs are only available to UIUC Users without author permissionU of I OnlyCrystallographic studies of high affinity anti-fluorescein monoclonal antibody 4-4-20 (K\sb{\rm a} = 1.7 10\sp{10} M\sp{-1}) complexed with fluorescyl ligand defined the six antibody active site contact residues involved in FI binding. For better definition of the relative role of each antigen contact residue in high affinity FI binding, each contact residue was changed to various amino acids in the single chain derivative of Mab 4-4-20 and following expression in Escherichia coli, denaturation, refolding and purification, each SCA (single chain antibody) mutant was characterized in terms of FI binding affinity, Q\sb{\rm max} (maximum fluorescein fluorescence quenching), \lambda\sb{\rm max} (Absorption maxima) and idiotype. Alanine substitutions at the six ligand-contact residues reduced the SCA binding affinities and quenching maxima for all the Ala mutants except L27d which retained wild type binding characteristics. Results of Ala substitution mutagenesis suggested that L32\sp{\rm Tyr}, L91\sp{\rm Ser} and H33\sp{\rm Trp} are most important for high affinity FI binding and efficient FI quenching. Substitution of Tyr and Phe at residue H33 resulted in binding affinities that were greater than that obtained from the H33\sp{\rm Ala} mutant and suggested that another aromatic amino acid could substitute for Trp this residue. A phenylalanine substitution at L32\sp{\rm Tyr}, which disrupted the Tyr hydrogen bond with fluorescyl ligand, resulted in a decreased the binding affinity (30-fold), but did not effect the quenching maxima. Finally, other amino acid substitutions at L34\sp{\rm Arg}, L91\sp{\rm Ser} and L27d\sp{\rm His} resulted in SCA mutants that possessed lower binding affinities and quenching maxima than that obtained for the respective Ala mutant.Primary structure comparisons of idiotypically cross-reactive Mabs 4-4-20, 9-40, 12-40 and 5-14 possessed identical FI contact residues with the exception of L34His for L34Arg. Site specific mutagenesis studies of SCA 4-4-20 in which L34Arg was changed to L34His resulted in 1000-fold and 3-fold decrease in binding affinity and Q\sb{\rm max}, respectively, which suggested that L34Arg was responsible for 4-4-20 increased binding affinity and fluorescence quenching. Collectively, these results suggest that the combining sites of Mab 9-40, 12-40 and 5-14 may possess different active site structures than Mab 4-4-20. (Abstract shortened by UMI.)Made available in DSpace on 2011-05-07T12:57:23Z (GMT). No. of bitstreams: 2
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An improved tabu-based vector optimal algorithm for design optimizations of electromagnetic devices
No full textAuthor name used in this publication: S. Y. YangAuthor name used in this publication: S. L. HoAuthor name used in this publication: J. M. MachadoAuthor name used in this publication: Edward W. C. Lo2003-2004 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishedVoR allowe
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