934 research outputs found
Human papillomavirus vaccine safety in Australia: experience to date and issues for surveillance
Australia was one of the first countries to licence a quadrivalent human papillomavirus (HPV) vaccine, rapidly followed by a federally funded program of universal vaccination of a broad age group of females through schools (12 to 18 years) and primary care (19 to 26 years). As of August 2009, more than 5.8 million doses of Gardasil® (quadrivalent; Merck, New Jersey, USA) have been distributed in Australia and a total of 1394 suspected adverse events following immunisation (AEFI) have been reported to the passive surveillance system. Most reports are of common and expected reactions. Case series of more uncommon and serious AEFI, both known to be potentially vaccine related (anaphylaxis, conversion disorders and lipoatrophy) and otherwise (multiple sclerosis and pancreatitis) have been published.Michael S. Gold, Jim Buttery and Peter McIntyr
Author Talk
University president, Jim Schmotter, introduces Tim O'Brien at the author talk in Ives Auditorium, October 26, 2010.</p
Febrile seizures following measles and varicella vaccines in young children in Australia
Abstract not availableKristine K. Macartney, Heather F. Gidding, Lieu Trinh, Han Wang, Jocelynne McRae, Nigel Crawford, Michael Gold, Anne Kynaston, Christopher Blyth, Zurynski Yvonne, Elizabeth Elliott, Robert Booy, Jim Buttery, Helen Marshall, Michael Nissen, Peter Richmond, Peter B. McInytre, Nicholas Woo
Architectural authorship in generative design
The emergence of evolutionary digital design methods, relying on the creative generation of novel forms, has transformed the design process altogether and consequently the role of the architect. These methods are more than the means to aid and enhance the design process or to perfect the representation of finite architectural projects. The architectural design philosophy is gradually transcending to a hybrid of art, engineering, computer programming and biology. Within this framework, the emergence of designs relies on the architect- machine interaction and the authorship that each of the two shares.
This work aims to explore the changes within the
design process and to define the authorial control of a
new breed of architects- programmers and architects-users on architecture and its design representation. For the investigation of these problems, this thesis is to be based on an experiment conducted by the author in order to test the interaction of architects with different digital design methods and their authorial control over the final product. Eventually, the results will be compared and evaluated in relation to the theoretic views. Ultimately, the architect will establish his authorial role
Jim Kalnin : Stream
Holubizky provides a time line of the germination and development of Kalnin’s exhibition. Writing in a personal, auto-biographical style, he addresses the major issues of Kalnin’s work, particularly the artist’s “regionalism,” since the artist is based in Kelowna. The author states that a personal approach like his own is best suited to comment on art. Kalnin also contributes an auto-biographical sketch (4 p.). 6 bibl. ref
Information systems for vaccine safety surveillance
Immunization implementation in the community relies upon post-licensure vaccine safety surveillance to maintain safe vaccination programs and to detect rare AEFI not observed in clinical trials. The increasing availability of electronic health-care related data and correspondence from both health-related providers and internet-based media has revolutionized health-care information. Many and varied forms of health information related to adverse event following immunization (AEFI) are potentially suitable for vaccine safety surveillance. The utilization of these media ranges from more efficient use of electronic spontaneous reporting, automated solicited surveillance methods, screening various electronic health record types, and the utilization of natural language processing techniques to scan enormous amounts of internet-based data for AEFI mentions. Each of these surveillance types have advantages and disadvantages and are often complementary to each other. Most are “hypothesis generating,” detecting potential safety signals, where some, such as vaccine safety datalinking, may also serve as “hypothesis testing” to help verify and investigate those potential signals
Uno Mas fanzine, Issue 10, 1995
The tenth issue of Uno Mas, a music fanzine that covered the punk and indie music scene in the Washington, D.C. area, as well as other music, art, and literature. This issue from 1995 includes interviews with musician Thurston Moore, the bands Guided By Voices and Liquorice, author George Pelecanos, musician and artist Bruce Licher, and an article on artist R. Crumb by Harvey Pekar. This issue also includes fiction, poetry, comics, photography, and reviews. Editor Jim Saah is notable for his work as a photographer, as well as his role as the cinematographer and editor of the 2014 documentary "Salad Days," which focused on the D.C. punk scene in the 1980s
Recurrence of extensive injection site reactions following DTPa or dTpa vaccine in children 4-6 years old
ObjectivesThe aim of this study was to compare the immunogenicity and reactogenicity of a lower dose diphtheria, tetanus and pertussis vaccine (dTpa) with the recommended vaccine (DTPa) given as a fifth dose to 4-6-year old children who previously experienced an extensive injection site reaction (ISR).Material and methodsChildren aged 4-6 years who had experienced an extensive ISR following a 4th dose of DTPa were recruited and randomly assigned to receive either the recommended DTPa or the lower dose dTpa vaccine. Parents recorded local reactions and systemic events for 15 days following vaccination. Immunogenicity was assessed pre and post vaccination by ELISA for diphtheria (D), tetanus (T), pertussis toxin (PT), filamentous haemagglutinin (FHA), and pertactin (PRN).ResultsA total of 53 participants were vaccinated. There was a 72% recurrence rate of ISR, with a trend (p=0.055) towards fewer ISR in the dTpa (61.5%) compared with the DTPa group (85.2%). There was no difference in reports of pain or irritability between groups. All participants had seroprotective levels of antibody to D and T and seroresponse to each of the 3 pertussis antigens following vaccination with higher GMCs in DTPa vs dTpa group. There was no increase in antibody avidity observed post vaccination, regardless of vaccine given.ConclusionRecurrence of ISR with the 5th dose of diphtheria, tetanus and pertussis vaccination in children who have previously experienced an extensive ISR is high. Vaccination with a dTpa vaccine may reduce the risk of fifth dose ISR.Patrick Quinn, Michael Gold, Jenny Royle, Jim Buttery, Peter Richmond, Peter McIntyre, Nick Wood, Su-san Lee, Helen Marshal
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