2,974 research outputs found
Snacks 45 -- Kyle Butler!
No full textIncludes descriptive metadata provided by producer in MP3 file: "Snacks 4 the Brain! - Podcasts - Snacks 45 -- Kyle Butler!"Vanderbilt Center for Science Outreac
Warfarin vs. Rivaroxaban in Long Term Acute Care Patients with Nonvalvular Atrial Fibrillation: A Budget Impact Analysis
No full textWarfarin Versus Rivaroxaban In Long Term Acute Care
Patients With Nonvalvular Atrial Fibrillation: A Budget Impact Analysis
Brian A. Bell Pharm.D. Candidate, Kyle M. Frantz Pharm.D. Candidate,
Brayton R. Jones Pharm.D. Candidate, Deborah Zeitlin Pharm.D.
Butler University College of Pharmacy and Select Specialty Hospital, Indianapolis, Indiana
Background: Atrial fibrillation (AF) is a common arrhythmia affecting over 2 million adult Americans. Historically, warfarin was the only oral anticoagulant available due to no other safe and effective Food and Drug Administration (FDA) approved oral agents. The potential cost savings of newer oral anticoagulants has not been studied in long term acute care institutions in clinical trials especially when compared to warfarin.
Study Objective: Retrospectively assess past treatment and management expenses at Select Specialty Hospital-Indianapolis and calculate overall costs when comparing warfarin to rivaroxaban therapy.
Hypothesis: There are potential cost savings when switching nonvalvular atrial fibrillation patients from warfarin to rivaroxaban.
Methods: Patient data and hospital treatment costs at Select Specialty Hospital-Indianapolis will be retrospectively analyzed via hospital medical records. Data collection on costs accrued by the hospital will include direct cost of medications to the hospital, cost of routine and acutely ordered lab testing, and other management expenses based on patients\u27 length of stay.
Study Subjects: Included patients must have been treated with either warfarin or rivaroxaban for nonvalvular atrial fibrillation on or after July 1, 2011. Patient stay must extend beyond 7 days, and patients must have a CHA2DS2VASC score of \u3e 2. Patients with contraindications to either warfarin or rivaroxaban or a history of recurrent stroke and ineligible for a therapy rechallenge will be excluded.
Results: Data collection is underway at this time. The results will be presented at the Butler University Undergraduate Research Conference.
Significance: Using new oral anticoagulants more presents an opportunity for long term acute care facilities to save on disease management costs; thus, establishing a cost-effective option that may provide budget savings. The study results may further help administrators make formulary decisions regarding oral anticoagulant treatment for patients with nonvalvular AF
Kyle Haselden
No full textKyle Emerson Haselden, D.D., Class of 1934, was a distinguished Baptist minister, author and editor. He authored three books, including 'The Racial Problem in Christian Perspective' published in 1959. He was also the editor of 'The Christian Century.' He is a Charter Member of the Furman University Hall of Fame
First person – Kyle Wegner
No full textFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Kyle Wegner is first author on ‘Edar is a downstream target of beta-catenin and drives collagen accumulation in the mouse prostate’, published in BIO. Kyle is a PhD candidate in the lab of Chad M. Vezina at the University of Wisconsin-Madison, investigating principles of toxicology and urology to evaluate mechanisms of urinary dysfunction in aging men
Warnock, Kyle
No full textKyle Warnock is a young queer person living in southern Maine whose non-profit, QueerlyME, has taken off to provide resources for the queer community in Maine. Starting as a photo documentary, QueerlyME is that, a resource directory and an event planning organization that focuses on queer activities outside of the traditional queer nightlife scene. Warnock talks about his experience growing up in South Dakota, coming out and the impacts of that. He also talks about his passion for connecting queer people with QueerlyME and the impact the organization has had on his life and the lives of many queer Mainers. Warnock strives towards making the outdoors more LGBTQ+ friendly.
Please cite as: Querying the Past: LGBTQ Maine Oral History Project Collection, Lesbian, Gay, Bisexual, Transgender, and Queer+ Collection, Jean Byers Sampson Center for Diversity in Maine, University of Southern Maine Libraries. For more information about the Querying the Past: Maine LGBTQ Oral History Project, please contact Dr. Wendy Chapkis.https://digitalcommons.usm.maine.edu/querying_ohproject/1097/thumbnail.jp
005 - Kyle Singer
No full textI highlight the importance of flaws, trauma, and repression by evoking concepts of “the unconscious” through surrealist methodologies. Considering all that is suppressed/repressed within my psyche to form the culturally accepted version of myself, and by examining the distance between my identity, and the repressed self. Engaging the viewers through superabundance, tackling issues of consumerism with construction that grapples with the excess of daily life. I question aesthetic value, moral responsibility, and political agency in my efforts to sublimate the abject. The abject touches on the fragility of our boundaries and the spatial distinction between our interiority and exteriority. My art stems from an insatiable appetite for new materials and compulsive ways I can explore new methods and processes. The impetus for my work is a cultural and political critique imbued with my own flavor of cynicism and disillusionment. I endeavor to destabilize perceptions by creating overwhelming masses of matter and meaning; meant to be all-consuming. This non-hierarchical kind of making causes a slow unraveling of my work allowing for an unpredictable composition and use of materials.The abject deals with a vast array of issues such as marginalized people, mortality, boundaries, and repulsion. It is usually used to describe the human reaction to horror and threatens to breakdown meaning by causing the loss of distinction between subject and object; between self and other. In an era of mass displacement due to natural and political disasters, this conceptually interest me and seem particularly relevant. The abject calls into question hierarchical values that allows for the dispersion and displacement of people: whether it be refugees, or low in-come families pushed out by gentrification. In the age of information, we have become incredibly efficient at codifying people and separating them from their personhood and seeing them only as replaceable objects with a set value; as a cluster of information to be used and exploited for profits. I plan to continue exploring the possibilities of media combination and new technologies. I am currently working with laser cutting, 3D printing, 3D scanning and the CNC machine. I am trying to explore new ways of misusing the machinery as a chance operation that allows the ebbs, flows, and limitations of the process itself to become a way of making. These new processes drastically change the way we think about construction and the possibilities of form. It blurs the boundaries between the hand-made and the mass-produced, dovetailing nicely with my ideas of consumerist cultural critique.College of Liberal Arts - Highest Achievement - Visual and Performing Arts
Gods, Spirits, People: Resource Collection
No full textThis collection of primary sources on Gods, Spirits, People in the early modern period accompanies the Gods, Spirits, People chapter. Curated Dr Andrew Redden and Dr Kyle Jackson, University of Liverpool.Collection of primary sourcesThis collection of primary sources on Gods, Spirits, People in the early modern period accompanies the Gods, Spirits, People chapter found at https://kora.kpu.ca/islandora/object/kora:579 and https://liverpooluniversitypress.manifoldapp.org/read/untitled-493687ea-d192-4880-b61e-19bd082917ba/section/0b9435bf-9209-45e7-bf35-81be5a2c3da
Linoleic acid causes greater weight gain than saturated fat without hypothalamic inflammation in the male mouse
No full textA significant change in the Western diet, concurrent with the obesity epidemic, was a substitution of saturated fatty acids with polyunsaturated, specifically linoleic acid (LA). Despite increasing investigation on type as well as amount of fat, it is unclear which fatty acids are most obesogenic. The objective of this study was to determine the obesogenic potency of LA vs. saturated fatty acids and the involvement of hypothalamic inflammation. Forty-eight mice were divided into four groups: low-fat or three high-fat diets (HFDs, 45% kcals from fat) with LA comprising 1%, 15% and 22.5% of kilocalories, the balance being saturated fatty acids. Over 12 weeks, bodyweight, body composition, food intake, calorimetry, and glycemia assays were performed. Arcuate nucleus and blood were collected for mRNA and protein analysis. All HFD-fed mice were heavier and less glucose tolerant than control. The diet with 22.5% LA caused greater bodyweight gain, decreased activity, and insulin resistance compared to control and 1% LA. All HFDs elevated leptin and decreased ghrelin in plasma. Neuropeptides gene expression was higher in 22.5% HFD. The inflammatory gene Ikk was suppressed in 1% and 22.5% LA. No consistent pattern of inflammatory gene expression was observed, with suppression and augmentation of genes by one or all of the HFDs relative to control. These data indicate that, in male mice, LA induces obesity and insulin resistance and reduces activity more than saturated fat, supporting the hypothesis that increased LA intake may be a contributor to the obesity epidemic.Peer reviewe
Cultural Manifesto/ Indianapolis Musician Kate Boyd
No full textKyle Long speaks with Indianapolis musician Kate Boyd about her recording of John Cage\u27s work for prepared piano. Link leads to the full broadcast but Kate\u27s interview starts at 4:17/1:00:00
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