566 research outputs found
DNA–Au (111) interactions and transverse charge transport properties for DNA-based electronic devices
No full textDNA's charge transfer and self-assembly characteristics have made it a hallmark of molecular electronics for the past two decades. A fast and efficient charge transfer mechanism with programmable properties using DNA nanostructures is required for DNA-based nanoelectronic applications and devices. The ability to integrate DNA with inorganic substrates becomes critical in this process. Such integrations may affect the conformation of DNA, altering its charge transport properties. Thus, using molecular dynamics simulations and first-principles calculations in conjunction with Green's function approach, we explore the impact of the Au (111) substrate on the conformation of DNA and analyze its effect on the charge transport. Our results indicate that DNA sequence, leading to its molecular conformation on the Au substrate, is critical to engineer charge transport properties. We demonstrate that DNA fluctuates on a gold substrate, sampling various distinct conformations over time. The energy levels, spatial locations of molecular orbitals and the DNA/Au contact atoms can differ between these distinct conformations. Depending on the sequence, at the HOMO, the charge transmission differs up to 60 times between the top ten conformations. We demonstrate that the relative positions of the nucleobases are critical in determining the conformations and the coupling between orbitals. We anticipate that these results can be extended to other inorganic surfaces and pave the way for understanding DNA-inorganic interface interactions for future DNA-based electronic device applications.We acknowledge NSF ECCS Grant Numbers 1807391 and 1807555. We acknowledge using the Hyak supercomputer system at the University of Washington and TUBITAK ULAKBIM, High Performance and Grid Computing Center (TRUBA resources). Busra Demir further acknowledges a TUBITAK 2214-A International Doctoral Research Fellowship.NSF ECCS [1807391, 1807555]; International Doctoral Research Fellowship [TUBITAK 2214-A
Demir Baba : saint et héros des musulmans hétérodoxes en Bulgarie
No full textL’auteur présente les kızılbaş en soulignant leur non-conformisme politique et leur messianisme. Situé dans ce contexte à partir de son vilayetname, Demir Baba fait alors l’objet d’une analyse historique et culturelle.The author sets out the kızılbaş by emphasizing their non-conformism and messanism. In this context, thanks to his vilayetname, Demir Baba is analyzed in an historical and cultural perspective
Demir Baba : saint et héros des musulmans hétérodoxes en Bulgarie
No full textL’auteur présente les kızılbaş en soulignant leur non-conformisme politique et leur messianisme. Situé dans ce contexte à partir de son vilayetname, Demir Baba fait alors l’objet d’une analyse historique et culturelle.The author sets out the kızılbaş by emphasizing their non-conformism and messanism. In this context, thanks to his vilayetname, Demir Baba is analyzed in an historical and cultural perspective
Approach for siting a support facility for transporting supplies in emergency cases in the Republic of Bulgaria
No full textIn this paper, the author determines the most suitable transportation location for intervention in a large scale disaster in the Republic of Bulgaria, by means of the Weber Problem and the Weiszfeld method. The objective is to minimise the cost of transporting emergency supplies across the country by locating a support facility, and thus reaching the area of event at the lowest possible cost. A brief description of the Weiszfeld method is provided in the paper. Further, using recent population data of both provinces and municipalities, the method is applied respectively to obtain the results. They were compared in terms of spatial correspondence and the final facility location was fixed. Erecting the supply site is recommended to help decrease the losses
Self-Aligning Nanojunctions for Integrated Single-Molecule Circuits
No full textLiu, Bo/0000-0003-4627-4456; Oren, Ersin Emre/0000-0001-5902-083X; Demir, Busra/0000-0002-3911-2291; Akin Gultakti, Caglanaz/0000-0002-0227-1002; Hihath, Joshua/0000-0002-2949-9293; Marrs, Jonathan/0000-0001-6434-2980Robust, high-yield integration of nanoscale components such as graphene nanoribbons, nanoparticles, or single-molecules with conventional electronic circuits has proven to be challenging. This difficulty arises because the contacts to these nanoscale devices must be precisely fabricated with angstrom-level resolution to make reliable connections, and at manufacturing scales this cannot be achieved with even the highest-resolution lithographic tools. Here we introduce an approach that circumvents this issue by precisely creating nanometer-scale gaps between metallic carbon electrodes by using a self-aligning, solution-phase process, which allows facile integration with conventional electronic systems with yields approaching 50%. The electrode separation is controlled by covalently binding metallic single-walled carbon nanotube (mCNT) electrodes to individual DNA duplexes to create mCNT-DNA-mCNT nanojunctions, where the gap is precisely matched to the DNA length. These junctions are then integrated with top-down lithographic techniques to create single-molecule circuits that have electronic properties dominated by the DNA in the junction, have reproducible conductance values with low dispersion, and are stable and robust enough to be utilized as active, high-specificity electronic biosensors for dynamic single-molecule detection of specific oligonucleotides, such as those related to the SARS-CoV-2 genome. This scalable approach for high-yield integration of nanometer-scale devices will enable opportunities for manufacturing of hybrid electronic systems for a wide range of applications.The authors acknowledge funding support from the National Science Foundation Future Manufacturing Program, Grant NSF-2036865/2328217, and the Keck Foundation. We also thank M. P. Anantram, William Livernois, and Yonggang Ke for fruitful discussions.Division of Chemical, Bioengineering, Environmental, and Transport Systems [NSF-2036865/2328217]; National Science Foundation Future Manufacturing Program; Keck Foundatio
Bibliometric analysis of the results of Reiki research
No full textIntroduction: This study analyses bibliometric indicators to assess global research trends on Reiki, including publication patterns and key contributing countries. Methods: The publications included in Web of Science (WOS) databases between 1970 and 2024 were reviewed. The WOS database was searched using TS= “REIKI” and all WOS indexes were included. This search identified 414 studies. Among them, letters (n = 7), editorial materials (n = 19), book reviews (n = 9), corrections (n = 2), art and poetry (n = 1), news (n = 1), and retracted publications (n = 1) were removed. The remaining 374 articles were included in this bibliometric analysis. The R-package for bibliometric analysis (Bibliometrix) was used. Results: The bibliometric analysis found that researchers published Reiki-related studies between 1983 and 2024, with a publication growth rate of 4.47 %. On average, articles were 9.5 years old and received 13 citations per document. The total number of keywords identified by the authors was 553, the number of authors in the articles was 1124 authors, the number of single-author articles was 70, the average number of publications per author was 3.5, and international co-authorships were 7.219 %. The USA, Brazil, the United Kingdom, Canada, and Turkiye were the top five countries that published on Reiki, respectively. The USA, Canada, the United Kingdom, Australia, and Turkiye were the top five countries with the most cited articles, respectively. Vitale A. is the most cited author. Journal of Alternative and Complementary Medicine is the most cited journal. Conclusion: This study is the first of its kind to evaluate the articles written by researchers in the field of Reiki only. Despite the difficulties researchers experienced in the field of Reiki, the studies have increasingly been conducted in this field over the years and have been cited studies more. This study may be helpful for researchers to determine productive countries, journals, authors, and emerging trends in Reiki by providing comprehensive analyses and structured information on this subject. © 202
Religious thought: Its religious economy, transformation, and future
No full text& Idot;shak Arslan's book titled Din Dusuncesi is a distinctive and original study compared to other works on religion in Turkish literature. Rather than focusing on religion itself, Arslan employs the concept of the "religious," which he defines as a form of generalized economy between the individual and the community. According to the author, the religious is structured around a "triadic spiral" composed of sacrifice, moderation, and hope. This triad distinguishes the religious from other forms of belief and spirituality. The book discusses the relationship between religion and economy, the functions of rituals, and the transformation of religion in the modern era. While presenting hedonism as the strongest rival to religion, it does not consider atheism or deism as genuine alternatives. This review highlights certain criticisms but emphasizes that Din D & uuml;& scedil;& uuml;ncesi makes an original and creative contribution to the literature
Performance of the Whale Optimization Algorithm in Space Steel Frame Optimization Problems
No full textInternational Conference on Harmony Search, Soft Computing and Applications (6. : 2020 : Istanbul, Turkey)Frame optimization that contains highly non-linear and irregular functions and discrete design variables is one of the most challenging optimization problems. Therefore, gradient-based optimization techniques cannot be successful in such problems. Metaheuristic techniques, especially population-based metaheuristic techniques, perform highly effective in solving the frame optimization problem. However, stochastic processes’ performances included in metaheuristic techniques vary based on the problem. Accordingly, researches on the performance of novel metaheuristic techniques on challenging engineering problems continue. One of the novel metaheuristic techniques is the whale optimization algorithm (WOA) which is inspired by the bubble-net feeding behavior of humpback whales. The aim of this study is testing the performance of WOA for space steel frame optimization problems. For this purpose, WOA-cased frame optimization program will be developed. Benchmark frame structures are selected to compare optimum solutions with literature results. © 2021, The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.No sponso
Effects of curvature-Higgs coupling on electroweak fine-tuning
No full textAbstractIt is shown that nonminimal coupling between the Standard Model (SM) Higgs field and spacetime curvature, present already at the renormalizable level, can be fine-tuned to stabilize the electroweak scale against power-law ultraviolet divergences. The nonminimal coupling acts as an extrinsic stabilizer with no effect on the loop structure of the SM, if gravity is classical. This novel fine-tuning scheme, which could also be interpreted within Sakharov's induced gravity approach, works neatly in extensions of the SM involving additional Higgs fields or singlet scalars
Evaluation of Spiritual Care and Well-Being Levels of Individuals Diagnosed with Lung Cancer in Turkey
No full textThis study aimed to assess the spiritual care needs and spiritual well-being levels of lung cancer patients undergoing chemotherapy (CT). This descriptive cross-sectional study was conducted with 110 patients in the outpatient CT unit of a university hospital. Data were collected using a personal information form, the “Three-Factor Spiritual Well-Being Scale” and the “Spiritual Care Needs Scale.” The average age of participants was 62.6 ± 8.0 years. Patients with a university or above education level, civil servants, self-employed individuals, those receiving only CT, and those with less than 5 CT cycles had significantly higher spiritual well-being scores (p < 0.05). Spiritual care needs scale scores were significantly higher for married individuals and those receiving only CT (p < 0.05). In conclusion, both spiritual well-being levels and spiritual care needs were observed to be high among lung cancer patients. © The Author(s) 2024
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