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Justin Busche
Photograph used for a story in the Daily Oklahoman newspaper. Caption: "Justin Busche gets plenty of playing time as Ada's punter and member of the marching band.
Zur Entstehung einer Imbalance im limbo-präfrontalen System bei Meriones unguiculatus : der Einfluss restriktiver Isolationsaufzucht und einer postnatalen Methamphetamin-Intoxikation auf die monoaminergen Transmitter Dopamin und Serotonin
Busche A. Zur Entstehung einer Imbalance im limbo-präfrontalen System bei Meriones unguiculatus : der Einfluss restriktiver Isolationsaufzucht und einer postnatalen Methamphetamin-Intoxikation auf die monoaminergen Transmitter Dopamin und Serotonin. Bielefeld (Germany): Bielefeld University; 2004.Schädigende Umwelteinflüsse können zu massiven Störungen der Hirnreifung führen. Störungen im limbo-präfrontalen System, welches als das höchste assoziative System des Gehirns gilt, werden mit verschiedenen psychischen Erkrankungen in Verbindung gebracht. An unserem Tiermodell (Meriones unguiculatus) konnte durch frühere Arbeiten gezeigt werden, dass sowohl eine chronische Schädigung in Form der restriktiven Isolationsaufzucht als auch eine akute Schädigung in Form der einmaligen Methamphetamin-Intoxikation am postnatalen Tag 14 Einfluss nehmen auf die Reifung der Monoamine Dopamin (DA) und Serotonin (5HT) im präfrontalen Kortex und Nucleus accumbens.
Ziel dieser Arbeit war es, den Einfluss dieser beiden experimentellen Parameter auf die postnatale DA und 5HT Reifung in der Formatio hippocampalis zu untersuchen und darüber hinaus ein Gesamtbild der Veränderungen dieser Monoamine innerhalb des limbo-präfrontalen Systems zu erstellen.
Insgesamt zeigt sich, dass beide Transmitter, DA und 5HT, in allen untersuchten Arealen des limbo-präfrontalen Systems in ihrer postnatalen Reifung stark beeinflusst werden. Insbesondere die strukturellen Veränderungen der DAergen Projektionen im limbo-präfrontalen System weisen auf eine, sich im Laufe des Reifungsprozesses entwickelnden, Imbalance innerhalb dieses Systems hin, die in Form einer Hypoinnervation des präfrontalen Kortex und einer Hyperinnervation des entorhinalen Kortex und der Amygdala auftritt. Lokale Veränderungen der monoaminergen Innervation können sowohl die Aktivitäten innerhalb der einzelnen Regionen als auch die Konnektivität zwischen den einzelnen Arealen beeinträchtigen und somit die Funktion des Gesamtsystems erheblich stören. Unsere Befunde unterstützen aktuelle Modellvorstellungen zur Schizophrenie, die eine Hypoaktivierung des präfrontalen Kortex und eine Hyperaktivierung limbischer Areale postulieren
Supplemental Material for Busche et al., 2019
Busche M, Pucker B, Viehöver P, Weisshaar B, Stracke R. Supplemental Material for Busche et al., 2019. GSA Journals; 2019.Version 2
File S1. Per chromosome read coverage distribution of Dwarf Cavendish reads.
File S2. Comparison of SNVs in the duplicated segment on the long arm of chromosome 2 to all other SNVs in the genome. The higher read coverage at variants indicates a duplication of this region.
File S3. List of public genomic banana sequence read samples used for comparison against Dwarf Cavendish based on the DH Pahang reference.
File S4. Coverage plots of public genomic banana sequence read samples (File S1) for comparison against Dwarf Cavendish based on the DH Pahang reference. Samples are: Musa acuminata, Musa acuminata AYP_BOSN_r1, Musa acuminata ssp. banksii, Musa acuminata ssp. burmannica, Musa acuminata Cavendish BaXiJiao, Musa acuminata Gros Michel, Musa acuminata ssp. malaccensis, Musa acuminata Sucrier (Pisang Mas), Musa acuminata Sucrier (Pisang Mas 1998-2307), Musa acuminata ssp. zebrina (blood banana), Musa balbisiana Pisang Klutuk Wulung, Musa itinerans, Musa schizocarpa.
File S5. List of selected high impact variants between Dwarf Cavendish and DH Pahang with resulting effects predicted by SnpEff.</br
Busche (Miss), S L K, Japan
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/375088Surname: BUSCHE (MISS)
Given Name(s) or Initials: S L K
Military Service Number or Last Known Location: JAPAN
Missing, Wounded and Prisoner of War Enquiry Card Index Number: 20090187064
Item: [2016.0049.07396] "Busche (Miss), S L K, Japan
Busche, Elwood A.; Interview and Materials
Roster Number: 1582. Picture Location: Box 9 Folder 4. Interview Location: Box 5 Folder 4
How does a quadratic term in the energy dispersion modify the single-particle Green's function of the Tomonaga-Luttinger model?
We calculate the effect of a quadratic term in the energy dispersion on the low-energy behavior of the Green's function of the spinless Tomonaga-Luttinger model (TLM). Assuming that for small wave-vectors q = k - k(F) the fermionic excitation energy relative to the Fermi energy is v(F)q + q(2)/(2m), we explicitly calculate the single-particle Green's function for finite but small values of lambda = q(c)/(2k(F)). Here k(F) is the Fermi wave-vector, q, is the maximal momentum transferred by the interaction, and v(F) = k(F)/m is the Fermi velocity. Assuming equal forward scattering couplings g(2) = g(4), we find that the dominant effect of the quadratic term in the energy dispersion is a renormalization of the anomalous dimension. In particular, at weak coupling the anomalous dimension is = gamma(1 - 2 lambda(2)gamma), where gamma is the anomalous dimension of the TLM. We also show how to treat the change of the chemical potential due to the interactions within the functional bosonization approach in arbitrary dimensions
Frequency-modulated continuous-wave radar processing fundamentals
In this thesis, we will discuss the techniques for determining distances, velocities, and angular position of targets using a frequency-modulated continuous-wave (FMCW) radar. FMCW radars have applications such as collision detection and assisted cruise control in modern vehicles, due to their ability to be manufactured as low-power, single-chip systems. We will discuss the use of a two-dimensional fast Fourier transform to efficiently compute the Doppler-range bins for a linear FMCW. A rudimentary geometric approach to angle estimation will then be discussed, followed by a look at the multiple signal classification (MUSIC) approach for angle estimation. Finally, we present the results of a simulated FMCW radar system with ideal targets for a variety of configurable system parameters.Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2020-02-28 without embargo termsThe student, Kirk Busche, accepted the attached license on 2019-12-11 at 18:18.The student, Kirk Busche, submitted this Thesis for approval on 2019-12-11 at 18:22.This Thesis was approved for publication on 2019-12-12 at 10:30.DSpace SAF Submission Ingestion Package generated from Vireo submission #14806 on 2020-02-28 at 17:16:56Made available in DSpace on 2020-03-02T22:03:27Z (GMT). No. of bitstreams: 2
BUSCHE-THESIS-2019.pdf: 578316 bytes, checksum: bec865d6d4d755fe20df60004351c7b6 (MD5)
LICENSE.txt: 4208 bytes, checksum: 5c64983c7fee733f586523aafe468c4a (MD5)
Previous issue date: 2019-12-1
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Functional Redundancy and Specialization of the Conserved Cold Shock Proteins in Bacillus subtilis
Faßhauer P, Busche T, Kalinowski J, et al. Functional Redundancy and Specialization of the Conserved Cold Shock Proteins in Bacillus subtilis. Microorganisms. 2021;9(7): 1434.Many bacteria encode so-called cold shock proteins. These proteins are characterized by a conserved protein domain. Often, the bacteria have multiple cold shock proteins that are expressed either constitutively or at low temperatures. In the Gram-positive model bacterium Bacillussubtilis, two of three cold shock proteins, CspB and CspD, belong to the most abundant proteins suggesting a very important function. To get insights into the role of these highly abundant proteins, we analyzed the phenotypes of single and double mutants, tested the expression of the csp genes and the impact of CspB and CspD on global gene expression in B. subtilis. We demonstrate that the simultaneous loss of both CspB and CspD results in a severe growth defect, in the loss of genetic competence, and the appearance of suppressor mutations. Overexpression of the third cold shock protein CspC could compensate for the loss of CspB and CspD. The transcriptome analysis revealed that the lack of CspB and CspD affects the expression of about 20% of all genes. In several cases, the lack of the cold shock proteins results in an increased read-through at transcription terminators suggesting that CspB and CspD might be involved in the control of transcription termination
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