28 research outputs found
sj-docx-1-chi-10.1177_17423953231161333 - Supplemental material for Chronic critical illness in critically ill COVID-19 patients
No full textSupplemental material, sj-docx-1-chi-10.1177_17423953231161333 for Chronic critical illness in critically ill COVID-19 patients by Burcin Halacli, Mehmet Yildirim, Esat Kivanc Kaya, Ege Ulusoydan, Ebru Ortac Ersoy and Arzu Topeli in Chronic Illness</p
sj-docx-1-jic-10.1177_08850666221131265 - Supplemental material for Assessment of Admission COVID-19 Associated Hyperinflammation Syndrome Score in Critically-Ill COVID-19 Patients
No full textSupplemental material, sj-docx-1-jic-10.1177_08850666221131265 for Assessment of Admission COVID-19 Associated Hyperinflammation Syndrome Score in Critically-Ill COVID-19 Patients by Mehmet Yildirim, Burcin Halacli, Deniz Yuce, Yunus Gunegul, Ebru Ortac Ersoy and Arzu Topeli in Journal of Intensive Care Medicine</p
Sequential assessment of septic patients for immune profiling: A focus on persistent inflammation, immunosuppression, and catabolism syndrome.
No full textHYPOPHOSPHATEMIA: UNRAVELING A LETHAL CONNECTION WITH ICU MORTALITY IN CRITICALLY ILL COVID-19 PATIENTS: A MULTICENTER OBSERVATIONAL STUDY
No full textBackground: Despite a lack of sufficient knowledge about the prevalence and impact of hypophosphatemia in critically ill COVID-19 patients, organ dysfunction, adverse clinical outcomes, and increased mortality have been consistently associated with hypophosphatemia across diverse patient populations. This retrospective, observational study aimed to investigate hypophosphatemia (HypoP) frequency and establish the correlation between variations in serum phos-phorus levels and outcomes in critically ill patients with SARS-CoV-2. Methods: The research comprised 205 patients diagnosed with COVID-19 confirmed via RT-PCR. The study included COVID-19 patients who experienced respiratory failure and were in intensive care for more than 24 hours, and their phosphorus values were accurately documented. Clinical parameters, comorbidities, respiratory support require-ments, and laboratory findings were analysed. Results: The study participants had a median age of 64 (IQR: 54-75 years), with hypertension being the most pre-valent chronic disease (46%). During the first three days of intensive care, 33% of the participants received conven-tional oxygen support, whereas 54% required intubation and mechanical ventilation (MV). During this period, hypo-phosphatemia was noted in 25% of patients, with an ICU admission median serum phosphorus level of 1.02 (0.87-1.25) mmol/L. The median duration of stay in the intensive care unit (ICU) was 7 days, significantly extended in patients with hypophosphatemia (p=0.046). Phosphorus levels on the third day of ICU stay were an independent predictor of ICU mortality. (COX, HR=1.48, 95% CI=1.11-1.98, p=0.006) Conclusions: During the first three days of ICU admission, 25% of SARS-CoV-2 critically ill adult patients presented with hypophosphatemia. This condition was found to increase ICU mortality rates and prolong ICU stays. Therefore, it is crucial to monitor serum phosphorus levels in the care of critically ill COVID-19 patients
Daily Surveillance With Early Warning Scores Help Predict Hospital Mortality In Medical Wards
No full textBackground/aim: To analyze the potency of a modified early warning score (EWS) to help predict hospital mortality when used for surveillance in nonacute medical wards. Materials and methods: Patients in internal medicine wards were prospectively recruited. First, highest, and last scores; and mean daily score recordings and values were recorded. Nurses calculated scores for each patient upon admission and every 4 h. The last score was the score before death, discharge, or transfer to another ward. The highest scores in total and for each single parameter were used for analysis. 9 Results: Fifty-nine percent of 182 recruited patients had recordings eligible for data analysis. Patients admitted from the emergency room had higher mortality rates than patients admitted from outpatient clinics (15% vs. 1.5%; P = 0.01) as well as patients whose first (40% vs. 4.9%; P = 0.033) and highest scores (18.8% vs. 1.3%; P = 0.003) were equal to or more than 3. The first recorded EWS was not predictive for mortality while the maximum score during the admission period was. Conclusion: This study underlines the fact that each physiological variable of EWS may not have the same weight in determining the outcome.WoSScopu
Assessment of Admission COVID-19 Associated Hyperinflammation Syndrome Score in Critically-Ill COVID-19 Patients
No full textPURPOSE: We aimed to evaluate the relation between admission COVID-19 associated hyperinflammatory syndrome (cHIS) score and intensive care unit (ICU) outcomes. MATERIALS AND METHODS: Patients with laboratory confirmed COVID-19 admitted to our ICU between 20(th) March 2020-15(th) June 2021 were included. Patients who received immunomodulatory treatment except corticosteroids were excluded. Main outcomes were ICU mortality and invasive mechanical ventilation (IMV) requirement after ICU admission. RESULTS: Three hundred and seventy patients with a median (IQR) age of 66 (56-77) were analyzed. Median admission cHIS score was 3 (2-4). A cHIS score ≥3 was found to be associated with ICU mortality (sensitivity = 0.63, specificity = 0.50; p < 0.01) and IMV requirement after ICU admission (sensitivity = 0.61, specificity = 0.51; p < 0.01). Patients with an admission cHIS score ≥3 (n = 199) had worse median admission APACHEII, SOFA scores and PaO(2)/FiO(2) ratio than others (n = 171) (p < 0.01). IMV requirement after ICU admission (38.5% vs 26.1%;p = 0.03), ICU (36.2% vs 25.1%;p = 0.02), hospital (39.1% vs 26.9%;p = 0.01) and 28th day (28.1% vs 19.1%;p = 0.04) mortality were higher in patients with admission cHIS score ≥3 than others (p < 0.01). Age <65 years, malignancy and higher admission SOFA score were independent variables associated with admission cHIS score ≥3. CONCLUSION: Critically-ill COVID-19 patients with admission cHIS score ≥3 have worse disease severity and outcomes than other patients
Nutritional practices in medical intensive care units: Multicenter, one-day point prevalence study* Pratiques nutritionnelles dans les unités de soins intensifs médicaux : étude de prévalence ponctuelle multicentrique sur une journée
No full textBackground/Aim. - Nutritional planning is an important aspect of Intensive Care Unit (ICU) care. The present study aimed to evaluate the nutritional practices adopted in medical ICUs in Turkiye and to investigate their compliance with current international guidelines. Methods. - This multicenter, cross-sectional study was performed on a predetermined study date. Centers were required to fill three groups of questionnaires: One on ICU characteristics and facilities, one on patients included, and one on outcomes of patients. Forms on patients had questions on demographics and their nutritional status. Results. - A total of 12 sites participated and 132 patients were recorded in the study and 109 patients were included in analyses. The median age was 72 [57-83] years and 55 (50%) of them was female. The median APACHE II score was 23 [18-29], median SOFA score was 6 [4-9] and median BMI was 25.32 [21.22-29.38]. More than 50% of patients were fed enterally; for most, it was started within the first 24 hours of admission. On the study day, the median energy intake of the patients during the last 24 hours was 21.62 [15.9-27.3] kcal/kg and the median amount of protein intake was 1.02 [0.7-1.3] g/kg, representing 83.1% and 78.9% of the targets, respectively. A total of 64 (58.7%) patients were alive on the 28th day of the study, of them 23 (21.1% of all patients) were still in the ICU
Are Risk Scores Applicable in Tertiary Veno-Venous Extra-Corporeal Membrane Oxygenation Centers?
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