1,721,287 research outputs found
Needling the waterbags? Who, where when, what and why
Overview of the current indications and contraindication of percutaneous treatments for echinococcal cyst
Clinica delle parassitosi epatobiliari
Il corso descrive le infezioni parassitarie che causano lesioni macroscopiche nel fegato e nelle vie biliari.
Oggi, la diagnostica per immagini e le nuove tecniche laboratoristiche ne permettono una diagnosi e un
trattamento più rapidi.
Purtroppo, molte delle patologie discusse sono importate da zone endemiche in aree tropicali e i clinici dei
paesi industrializzati hanno scarsa familiarità con esse. Il corso ha quindi lo scopo di sopperire alle carenze
formative, fornendo dettagli sulla diagnosi per immagini e di laboratorio, e presentando i dati più recenti
relativi all’epidemiologia, alla modalità di trasmissione, alle caratteristiche cliniche di queste patologie e al
loro trattamento
Update on cystic hydatid disease.
PURPOSE OF REVIEW:
Cystic echinococcosis, or cystic hydatidosis, is a complex, chronic disease with a cosmopolitan distribution. In humans, its clinical spectrum ranges from asymptomatic infection to severe, rarely even fatal disease. Four approaches in clinical management exist: surgery, percutaneous techniques and drug treatment for active cysts, and the so-called watch and wait approach for inactive cysts. Allocation of patients to these treatments should be based on cyst stage, size and location, available clinical expertise and comorbidities. However, clinical decision algorithms, efficacy, relapse rates, and costs have never been properly evaluated.We review the currently available evidence for clinical decision-making and discuss ways to improve standards of care of one of the most neglected infectious diseases.
RECENT FINDINGS:
Data are mostly derived from case series and small clinical trials, and treatment guidelines remain at the level of expert opinion. No single high-quality comparative clinical trial of the four treatment options is available to resolve important questions such as stage-specific allocation of treatments, adverse events and long-term relapse rates. Recent work is beginning to acknowledge this problem.
SUMMARY:
Currently, four treatment modalities are available for cystic echinococcosis. The level of evidence on which clinicians have to rely is low. For the time being patients should thus be treated in referral centres. Proper comparative clinical trials are urgently needed
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