809 research outputs found
A Laminin-2, Dystroglycan, Utrophin Axis Is Required for Compartmentalization and Elongation of Myelin Segments
No full textAnimal and plant cells compartmentalize to perform morphogenetic functions. Compartmentalization of myelin-forming Schwann cells may favor elongation of myelin segments to the size required for efficient conduction of nerve impulses. Compartments in myelinated fibers were described by Ramon y Cajal and depend on periaxin, mutated in the hereditary neuropathy Charcot-Marie-Tooth disease type 4F (Charcot-Marie-Tooth 4F). Lack of periaxin in mice causes loss of compartments, formation of short myelin segments (internodes) and reduced nerve conduction velocity. How compartments are formed and maintained, and their relevance to human neuropathies is largely unknown. Here we show that formation of compartments around myelin is driven by the actin cytoskeleton, and maintained by actin and tubulin fences through linkage to the dystroglycan complex. Compartmentalization and establishment of correct internodal length requires the presence of glycosylated dystroglycan, utrophin and extracellular laminin-2/211. A neuropathic patient with reduced internodal length and nerve conduction velocity because of absence of laminin-2/211 (congenital muscular dystrophy 1A) also shows abnormal compartmentalization. These data link formation of compartments through a laminin2, dystroglycan, utrophin, actin axis to internodal length, and provide a common pathogenetic mechanism for two inherited human neuropathies. Other cell types may exploit dystroglycan complexes in similar fashions to create barriers and compartments
Book Review: Team America: Patton, MacArthur, Marshall, Eisenhower, and the World They Forged
No full textAuthor: Robert L. O’Connell
Reviewed by Rev. Dr. Wylie W. Johnson, US Army War College class of 2010
Although early twentieth-century America’s Army was small, meagerly funded, short on equipment, and rife with other struggles, it saw the rise of great leaders. Team America: Patton, MacArthur, Marshall, Eisenhower, and the World They Forged focuses on four of them. They came from different backgrounds, yet “Together they accounted for 19 stars; together they brought about victory in their generation. Two became Chief of Staff of the Army. One rose to become the US Commander in Chief.”https://press.armywarcollege.edu/parameters_bookshelf/1021/thumbnail.jp
The Smithfield Review
No full textAn examination of five previously undiscovered manuscripts about Patton located by the author. This material contributes several maritime exploits, including a daring escape from Cornish pirates and adds to known existing biographical data of Patton
Holub R. C. Nietzsche and the Women’s Question / trans. from Engl. R. L. Kochnev
No full textThe article discusses collections of scientific papers edited by Paul Patton and Peter
Burgard on the subject of the philosophy of Friedrich Nietzsche and modern ideas
of the feminist tradition. Both collections contain debates about the ambiguity of
the heritage of the German thinker in ethical and political thought. This review
provides an analysis of the articles and approaches they use. The author criticized
the tendencies to simplify Nietzsche’s philosoph
2003. Countering misinformation concerning big sagebrush. USDA-Forest
No full text). The authors state and discuss eight purported "axioms" regarding the ecology and management of big sagebrush. Publication of this report has generated a great deal of interest about the present state of science regarding big sagebrush and its relation to fire, grazing, and wildlife habitat. In addition, concerns have been expressed about some of the interpretation and analyses contained in the paper and the language in which they are expressed. The views expressed by the authors are their own and do not reflect the policy or views of the USDA Forest Service. We acknowledge and respect the concerns that have been expressed about the tone and language used in this paper, and apologize to anyone who might have been offended. This would normally not have passed peer and policy review prior to publication by the Rocky Mountain Research Station. We strive to be a source of quality and unbiased scientific information. In light of the large distribution this publication has already received, I believe it is important to take positive action to provide opportunity for rebuttal and to publish a subsequent document that more broadly clarifies the debate and uncertainty about the ecology of big sagebrush. The Rocky Mountain Research Station is in the final stages of publishing a thorough book-length synopsis of current information on big sagebrush by Dr. Bruce L. Welch. We have completed extensive scientific peer review and careful policy review of this book, and this new publication will be a more complete and authoritative reference on the ecology of big sagebrush. In response to the interest and debate expressed related to the initial paper and in recognition of the considerable uncertainty that remains in the scientific literature regarding the larger science issues about big sagebrush, we invite interested scientists to help us better present a diversity of views on this topic. During the next year, we will assemble and publish a subsequent paper that discusses these issues further and helps provide a broader understanding and synthesis of the areas of disagreement on ecology and management of big sagebrush. We will include alternative perspectives on the "axioms" contained in the paper by Welch and Criddle, and also seek to achieve a level of synthesis and consensus as to the present scientific understanding, what areas of uncertainty and disagreement remain, and what research is needed to help resolve these uncertainties. To express your views, to clarify debate on these topics, and to indicate your interest in participating as an author or co-author for the subsequent paper, please contact Dr. Jack B. Waide, Assistant Station Director for Research at (801) 625-5406 or e-mail [email protected]. We would appreciate receiving your input no later than January 30, 2004. This paper examines the scientific merits of eight axioms of range or vegetative management pertaining to big sagebrush. These axioms are: (1) Wyoming big sagebrush (Artemisia tridentata ssp. wyomingensis) does not naturally exceed 10 percent canopy cover and mountain big sagebrush (A. t. ssp. vaseyana) does not naturally exceed 20 percent canopy cover; (2) As big sagebrush canopy cover increases over 12 to15 percent, bare ground increases and perennial grass cover decreases; (3) Removing, controlling, or killing big sagebrush will results in a two or three or more fold increase in perennial grass production; (4) Nothing eats it; (5) Biodiversity increases with removing, controlling, thinning, or killing of big sagebrush; (6) Mountain big sagebrush evolved in an environment with a mean fire interval of 20 to 30 years; (7) Big sagebrush is an agent of allelopathy; and (8) Big sagebrush is a highly competitive, dominating, suppressive plant species
1972 Jay-Cee-An BJC -- Page 112
No full textPhotographs of BJC freshmenNolz, Aloysius J.
Nystedt, Doreen R.
O'Brien, Patrick D.
Oberg, Sandra L.
Oberlander, Marlene E.
Oberlander, Rodney A.
O'Callaghan, Renee M.
Oelke, Cynthia K.
Okerson, Karen C.
Olheiser, Judy A.
Olson, Judith E.
Olson, Randy R.
Olson, Renee D.
Olson, Robert L.
Onstad, Kenton B.
Orser, Nancy A.
Osborn, Don P.
Osborn, Scott C.
Oster, Deborah J.
Ottmar, Perry L.
Otto, Bonita F.
Owens, Owen L.
Parkes, Larry R.
Patton, Colleen A.
Patton, Mary J.
Paul, Hollu J.
Paul, Thomas V.
Paul, William H.
Payne, Cynthia R.
Pederson, Kathryn E.
Peel, Jeffrey S.
Peightal, Stephen K.
Peterson, Bruce P.
Petryszyn, Evelyn M.
Pettis, Etta Ann
Prarr, Terry J.
Phillips, Mary F.
Pittenger, Wesley G.
Pitzer, Fay A.
Polensky, Ronald W.
Pope, Elaine C.
Poppke, Kathleen D.
Porsborg, Pa tti G.
Parten, Carol
Porter, Judith D.
Post, Wanda J.
Preszler, Da vie L.
Quast, Jennifer K.
Quinlan, Hal M.
Quinn, Michael L.
Rader, Gary L.
Rasmussen, Sharon D.
Raszler, Jeannette K.
Rauscher, Debbie R.
Ray, Nancy D.
Reeck, Steve R.
Reetz, Harvey H.
Reimnitz, Andrew G.
Reirnnitz , Brenda K.
Reimnitz, Bryan D.
Reiner, Monte R.
Reiner, Tim
Reinhardt, Gary
11
Beta Theta Pi [05]
No full textGroup picture of Beta Theta Pi. Front row L-R: Bob Hemlick, Bob Livingston, Kendall King, Tim Daley, Clair Kanaston, Mike Boles, Bill Stowe, David Munn, Ed Kale. Row 2 L-R: Bob Kopke, Neal Newhouse, Lee Griffin, Lance Johnson, Art Lindemer, Jim Golden, Garth Brown, Gale Conrad, Lauri Fowler, Joe Komen, Jim Richel. Row 3 L-R: Frank Cammack, Brent Burningham, Tom Ratcliffe, Dick Wyatt, Jerry Gneckow, Bill Deal, Mrs. Cummins, Mike Patton, Norm Howse, Dave Eskelin, Bill Boyce, Rich Kalferd. Row 4 L-R: Wiley Wagner, Tom Reveley, Tom Rudy, Skip Ward, Tim Green, Tom Scharf, Reg Corolan, Ron Lichau, Pat McQuade, J.S.G., Jon Nilson, Bruce Cairns, Bruce McCowan, Stu Robertson, Dave Maxey, Barry Thielke. Row 5 L-R: Denny McLean, Ron Hunt, Lee Miller, Herb Carlson, Gordon Gray, Don Modie, Knute Westergren, John West, John Arduser, Jack Little, Gorden Fowler, Danny Langdon, Grahm Knox, Mike Killien. Row 6 L-R: Randy Litton, Larry Parberry, Arny Skov, Burt Allen, Bob Hansen, Kent Hove, Stan Pierce
Libraries Can Go Green
No full textMy Turn essay on ways that libraries can be more environmentally responsible.not peer reviewedSubmitted by Laura Barnes ([email protected]) on 2009-04-09T17:52:22Z
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Previous issue date: 2008-10published or submitted for publicatio
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