324 research outputs found
Bertram C. Broome to Horace Kephart, January 11, 1924
No full textIn a letter to Horace Kephart on January 11, 1924, Bertram C. Broome wishes to know the location of a junk shop dealer to purchase a muzzle loading mountaineer rifle in good condition. Mr. Broome describes his gun collection and seeing Woodmansee’s rifles
Bertram C. Broome to Horace Kephart, March 31, 1924
No full textIn a letter to Horace Kephart on March 31, 1924, Bertram C. Broome describes winter weather in Connecticut and his rifle collection. He also tells Kephart about his life in New Mexico, Texas, Mexico, and New York
Editorial for progressive education: Antecedents of educating for democracy
No full textJournal Articl
Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies
Full text linkThe application of a 1H nuclear magnetic resonance (NMR) spectroscopy-based screening method for determining the use of two widely available analgesics (acetaminophen and ibuprofen) in epidemiologic studies has been investigated. We used samples and data from the cross-sectional INTERMAP Study involving participants from Japan (n = 1145), China (n = 839), U.K. (n = 501), and the U.S. (n = 2195). An orthogonal projection to latent structures discriminant analysis (OPLS-DA) algorithm with an incorporated Monte Carlo resampling function was applied to the NMR data set to determine which spectra contained analgesic metabolites. OPLS-DA preprocessing parameters (normalization, bin width, scaling, and input parameters) were assessed systematically to identify an optimal acetaminophen prediction model. Subsets of INTERMAP spectra were examined to verify and validate the presence/absence of acetaminophen/ibuprofen based on known chemical shift and coupling patterns. The optimized and validated acetaminophen model correctly predicted 98.2%, and the ibuprofen model correctly predicted 99.0% of the urine specimens containing these drug metabolites. The acetaminophen and ibuprofen models were subsequently used to predict the presence/absence of these drug metabolites for the remaining INTERMAP specimens. The acetaminophen model identified 415 out of 8436 spectra as containing acetaminophen metabolite signals while the ibuprofen model identified 245 out of 8604 spectra as containing ibuprofen metabolite signals from the global data set after excluding samples used to construct the prediction models. The NMR-based metabolic screening strategy provides a new objective approach for evaluation of self-reported medication data and is extendable to other aspects of population xenometabolome profiling
Toward Functional Augmented Reality in Marine Navigation: A Cognitive Work Analysis
No full textAugmented Reality, (AR) also known as vision-overlay, can help the navigator to visually detect a dangerous target by the overlay of a synthetic image, thus providing a visual cue over the real world. This is the first paper of a series about the practicalities and consequences of implementing AR in marine navigation. A Cognitive Work Analysis is carried out to derive a scientific base for a functionalinterface that best supports navigators in their work.Control & SimulationControl & Operation
Using Augmented Reality to Improve Collision Avoidance and Resolution
No full textBased on the Cognitive Work Analysis, described in a previous paper, an Ecological Interface is designed and built for the Augmented Reality application at Willem Barentsz. Incorporated, a.o., is the concept of Velocity Obstacles. This innovative way to visualize the problem space and solution space, provides the navigator with real time information about the possible combinations of course and speed that avoid intrusion into an other ship’s protected zone. Hence, it is anticipated that this will result in better Situation Awareness, leading to less close encounters, a.k.a. near misses, and fewer collisions.Control & Simulatio
doi:10.1016/j.bulm.2003.12.005 ACalcium-based Phantom Bursting Model for Pancreatic Islets
No full textInsulin-secreting β-cells, located within the pancreatic islets of Langerhans, are excitable cells that produce regular bursts of action potentials when stimulated by glucose. This system has been the focus of mathematical investigation for two decades, spawning an array of mathematical models. Recently, a new class of models has been introduced called ‘phantom bursters ’ [Bertram et al. (2000) Biophys. J. 79, 2880–2892], which accounts for the wide range of burst frequencies exhibited by islets via the interaction of more than one slow process. Here, we describe one implementation of the phantom bursting mechanism in which intracellular Ca 2+ controls the oscillations through both direct and indirect negative feedback pathways. We show how the model dynamics can be understood through an extension of the fast/slow analysis that is typically employed for bursting oscillations. From this perspective, the model makes use of multiple degrees of freedom to generate the full range of bursting oscillations exhibited by β-cells. The model also accounts for a wide range of experimental phenomena, including the ubiquitous triphasic response to the step elevation of glucose and responses to perturbations of internal Ca 2+ stores. Although it is not presently a complete model of all β-cell properties, it demonstrates the design principles that we anticipate will underlie future progress in β-cell modeling. c ○ 2004 Society for Mathematical Biology. Published by Elsevier Ltd. All rights reserved. ∗ Author to whom correspondence should be addressed
Sustaining Inquiry in an After -School Science and Design Lab: The Significance of the Parts Ecology
No full text162 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2004.Through a detailed analysis of the use of artifacts within two informal learning environments, the author finds that the choices made by participants in response to the distribution and abundance of those artifacts determine to a large extent the sustainability of inquiry learning. Reflecting upon the importance of the use of metaphor in uncovering troubling events and attitudes in these environments, the author concludes with a discussion of the responsibilities of participants in the context of self-study and narrative inquiry.U of I OnlyRestricted to the U of I community idenfinitely during batch ingest of legacy ETD
Living reading: The mutual construction of spirituality and reading
No full text"Using materials gathered from a one and one-half year ethnographic study of several local affiliates of the Illinois Reading Council, the author explores the multiple meanings of reading that emerged from the group's practice, to develop the notion of ""living reading."" The dissertation provides background on the historical contexts from which the reading councils developed and an overview of current local council practice. It focuses close attention on the symbols, forms, rituals, genres, and discourses through which notions of reading are articulated in council practice. The analysis demonstrates the close ties that exist between the councils and Protestant practice as it was articulated through the development of women's voluntary benevolent associations. It discusses the ways that, through council practice, reading becomes a means of spiritual self-expression and fulfillment that allows members to be both compliant and resistant to institutionally imposed restrictions on their personal and professional growth."Made available in DSpace on 2011-05-07T13:36:58Z (GMT). No. of bitstreams: 2
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Sustaining Inquiry in an After -School Science and Design Lab: The Significance of the Parts Ecology
No full textThrough a detailed analysis of the use of artifacts within two informal learning environments, the author finds that the choices made by participants in response to the distribution and abundance of those artifacts determine to a large extent the sustainability of inquiry learning. Reflecting upon the importance of the use of metaphor in uncovering troubling events and attitudes in these environments, the author concludes with a discussion of the responsibilities of participants in the context of self-study and narrative inquiry.Made available in DSpace on 2015-09-25T19:53:30Z (GMT). No. of bitstreams: 2
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Previous issue date: 2004Embargo set by: Seth Robbins for item 81055
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Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDsRestricted to the U of I community idenfinitely during batch ingest of legacy ETDsU of I Only162 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2004
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