86,961 research outputs found
Identification of diagnostic tumour markers and therapeutic targets in testicular tumours
Spatio-temporal topography of saccadic overestimation of time.
Rapid eye movements (saccades) induce visual misperceptions. A number of studies in recent years have investigated the spatio-temporal profiles of effects like saccadic suppression or perisaccadic mislocalization and revealed substantial functional similarities. Saccade induced chronostasis describes the subjective overestimation of stimulus duration when the stimulus onset falls within a saccade. In this study we aimed to functionally characterize saccade induced chronostasis in greater detail. Specifically we tested if chronostasis is influenced by or functionally related to saccadic suppression. In a first set of experiments, we measured the perceived duration of visual stimuli presented at different spatial positions as a function of presentation time relative to the saccade. We further compared perceived duration during saccades for isoluminant and luminant stimuli. Finally, we investigated whether or not saccade induced chronostasis is dependent on the execution of a saccade itself. We show that chronostasis occurs across the visual field with a clear spatio-temporal tuning. Furthermore, we report chronostasis during simulated saccades, indicating that spurious retinal motion induced by the saccade is a prime origin of the phenomenon
Rolf H. Bremmer, Jr. — The Fyve Wyttes : A Late Middle English Devotional Treatise Edited from BL MS Harlem 2398 with an Introduction, Commentary and Glossary, 1987 (" Costerus ", n.s. 65)
Blake N. F. Rolf H. Bremmer, Jr. — The Fyve Wyttes : A Late Middle English Devotional Treatise Edited from BL MS Harlem 2398 with an Introduction, Commentary and Glossary, 1987 (" Costerus ", n.s. 65). In: Cahiers de civilisation médiévale, 33e année (n°129), Janvier-mars 1990. pp. 69-70
Spatiotemporal profile of peri-saccadic contrast sensitivity
Sensitivity to luminance contrast is reduced just before and during saccades (saccadic suppression), whereas sensitivity to color contrast is unimpaired peri-saccadically and enhanced post-saccadically. The exact spatiotemporal map of these perceptual effects is as yet unknown. Here, we measured detection thresholds for briefly flashed Gaussian blobs modulated in either luminance or chromatic contrast, displayed at a range of eccentricities. Sensitivity to luminance contrast was reduced peri-saccadically by a scaling factor, which was almost constant across retinal space. Saccadic suppression followed a similar time course across all tested eccentricities and was maximal shortly after the saccade onset. Sensitivity to chromatic contrast was enhanced post-saccadically at all tested locations. The enhancement was not specifically linked to the execution of saccades, as it was also observed following a displacement of retinal images comparable to that caused by a saccade. We conclude that luminance and chromatic contrast sensitivities are subject to distinct modulations at the time of saccades, resulting from independent neural processes
Sex cord stromal tumors and tumors of the paratestis: new and old entities in a landscape of rare tumors
PURPOSE OF REVIEW: The 5th edition of WHO classification incorporates the most relevant new data available in the literature regarding tumors of the male genitourinary tract. In this review, the authors summarize and critically discuss the most relevant new information regarding tumors occurring in the stromal testis and in the paratestis that will be reported in the new edition of WHO classification of tumors of the male genitourinary tract. RECENT FINDINGS: Signet-ring stromal tumors (SRST) and myoid gonadal stromal tumors (MGST) are two new entities brought in the 5th WHO classification of testicular tumors. All cases of SRST and MGST reported so far have behaved in a benign fashion after resection and whenever possible a conservative surgery is recommended. A future perspective is to aim at creating large multiinstitutional case series to link different morphologic patterns and molecular bases to the biologic behavior of these neoplasms. Another innovation in WHO consists in the inclusion in the group of Sertoli cell tumors of the sertoliform cystadenoma. The sertoliform cystadenoma is localized in the rete testis and it is of unknown origin. It was included in the group of gonadal stromal tumors because of a high morphological and immunohistochemical similarity to the Sertoli cell tumor. SUMMARY: Although further studies with long-term follow-up are needed to estimate the main oncologic outcomes in patients with rare gonadal stromal tumors, we highlight the importance of an accurate characterization by molecular and immunohistochemical assays of these entities
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
[Newspaper Clipping: Author Claims Evidence of Second JFK Assassin #1]
Newspaper article titled "Author Claims Evidence of Second JFK Assassin." The article states that author Richard J. Whalen concluded "that there is circumstantial evidence to support the theory of a second assassin in the shooting of President John F. Kennedy.
Saccadic compression of symbolic numerical magnitude.
Stimuli flashed briefly around the time of saccadic eye movements are subject to complex distortions: compression of space and time; underestimate of numerosity. Here we show that saccadic distortions extend to abstract quantities, affecting the representation of symbolic numerical magnitude. Subjects consistently underestimated the results of rapidly computed mental additions and subtractions, when the operands were briefly displayed before a saccade. However, the recognition of the number symbols was unimpaired. These results are consistent with the hypothesis of a common, abstract metric encoding magnitude along multiple dimensions. They suggest that a surprising link exists between the preparation of action and the representation of abstract quantities
Sacred History And Sacred Texts In Early Judaism: A Symposium In Honour Of A.s. Van Der Woude
After a long and distinguished career Adam S. van der Woude will retire on Reformation Day (October 31) from the Chair of Old Testament Studies and Intertestamental Literature of the Faculty of Theology of the Rijksuniversiteit Groningen. In order not to let this occasion go unnoticed, the Center of Religious Studies decided to organise a symposium in honour of one of its best known members on the very day that he himself gave his valedictory lecture. In view of Adam's academic interests, it seemed therefore an obvious choice to focus the lectures on Jewish and Christian traditions in the Intertestamental period. In addition to devoting so much of his own time and energy to this subject, he has also promoted the interest of the scholarly world in this central period in the history of Judaism and Christianity by the foundation and editing of the Journal for the Study of Judaism in the Persian, Helknistic and Roman Period.
At the symposium, four friends and colleagues from Amsterdam, Groningen and Utrecht discussed various features of the history and literature of the Second Temple period. T. Baarda compares several traditions of the Shechem episode in the Testament of Levi. J.N. Bremmer enters into a recent debate on the origin of the Christian idea of the atonement. P.W. van der Horst analyses the reception or Ezekiel's words 'Laws that were not good' in early Judaism and Christianity, and M.A. Wes studies a fascinating episode from Flavius Josephus in the light of the Book
of Baruch.
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