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2. Genetic prothrombotic factors in children with otogenic lateral sinus thrombosis: five case reports
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Genetic prothrombotic factors in children with otogenic lateral sinus thrombosis: five case reports
Author(s): Zangari, P (Zangari, Paola)1; Messia, V (Messia, Virginia)1; Viccaro, M (Viccaro, Marika)2; Bottero, S (Bottero, Sergio)2; Randisi, F (Randisi, Francesco)3; Marsella, P (Marsella, Pasquale)2; Luciani, M (Luciani, Matteo)4; Locatelli, F (Locatelli, Franco)4
Source: BLOOD COAGULATION & FIBRINOLYSIS Volume: 23 Issue: 2 Pages: 158-163 DOI: 10.1097/MBC.0b013e328349cafb Published: MAR 2012
Times Cited: 0 (from Web of Science)
Cited References: 20 [ view related records ] Citation Map
Abstract: Lateral sinus thrombosis (LST) is an uncommon, but life-threatening complication of both acute and chronic otitis media. There is some evidence that acquired or hereditary prothrombotic disorders are risk factors for LST. The aim of this work was to evaluate the role of thrombotic screening, anticoagulant therapy or prophylaxis in patients with either acute or chronic otitis media and LST. The medical records of five children hospitalized at Pediatric Hospital Bambino Gesu of Rome because of acute or chronic otitis media complicated by mastoiditis and LST were reviewed. All children underwent laboratory workup for hypercoagulability. All the five children were found to be heterozygote for the C677T MTHFR mutation and a child presented also heterozygosity for factor V Leiden mutation. They have been successfully treated with anticoagulant therapy without sequels. Children with acute or chronic otitis media may have a prothrombotic tendency that becomes clinically evident because of the inflammatory state. Patients with a family and/or personal history of thrombosis and/or thrombophilic conditions need anticoagulant prophylaxis also in the absence of clear signs of LST. Treatment with low molecular weight is successful in patients with LST. Blood Coagul Fibrinolysis 23:158-163 (C) 2012 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins
G. Posener, J. Bottero, Kathleen M. Kenyon, Syria and Palestine c. 2160-1780 B. C. Extrait de The Cambridge Ancient History, vol. I, The University Press, 1965.
Parrot André. G. Posener, J. Bottero, Kathleen M. Kenyon, Syria and Palestine c. 2160-1780 B. C. Extrait de The Cambridge Ancient History, vol. I, The University Press, 1965.. In: Syria. Tome 44 fascicule 3-4, 1967. pp. 421-423
Integrating the analytic network process (ANP) and the driving force-pressure-state-impact- responses (DPSIR) model for the sustainability assessment of territorial transformations
PurposeThe paper, which is based on an integrated approach that is able to aid the comprehension of complex phenomena, aims to investigate innovative models and tools in the field of sustainability assessment of territorial transformations. The model has been applied to a real case study related to the choice of alternative projects for the requalification of a downgraded urban area in Turin (Italy).Design/methodology/approachThe work proposes the use of a comprehensive key environmental indicator framework and multi‐criteria analysis to evaluate the sustainability of different strategies. The evaluation has been performed through the application of the analytical network process (ANP) and by means of a set of indicators, which have been arranged according to the Driving Force‐Pressure‐State‐Impact‐Responses (DPSIR) framework. The assessment model provides priority lists of the importance of the considered indicators and alternatives. All the analysis elements are modelled with the ANP, taking into consideration the interconnections between the indicators and their respective cumulative importance.FindingsAccording to the aim of the paper, the most important element in the performed analysis refers to the variation of the well‐being of the population, followed by the changes in the accessibility and attractiveness of the area, then by the effects on the real estate market and the presence of new cycle tracks.Originality/valueThe work is the first study at a national level and one of the first applications at an international level in research concerning the use of the DPSIR framework integrated with an ANP analysis.</jats:sec
Combining an agent-based model, hedonic pricing and multicriteria analysis to model green gentrification dynamics
Household mobility dynamics are a complex phenomenon due to the multi-faceted human-environment interactions involved. These dynamics are affected by a variety of variables, spanning economic, structural, political and environmental. With respect to this latter aspect, much research has explored the relationship between the development of urban green areas, the increase of price and the formation of gentrification. Within this context, the present work explores housing mobility and gentrification dynamics proposing a mixed-method approach that combines a spatially explicit agent-based model (ABM), a Multicriteria Decision Analysis (MCDA) and a Hedonic Price (HP). The case study of the transformation project of Victoria Park in Brisbane (Australia) is used to verify the applicability of this integrated approach. In the methodological framework proposed, the ABM simulates the housing mobility of the residents through an individual decision-making process, where the likelihood of mobility is based on various empirical endogenous factors (i.e., household socio-economic characteristics) and exogenous ones (i.e., market variation). The MCDA supports the identification of the relative importance of these factors using a panel of local experts and stakeholders. The Spatial HP explores the impact of urban parks on real estate prices. The current study found the abilities of MCDA and HP to reduce the assumptions of ABM by generating quali-quantitative information of citizens' behaviors and estimating price increase. Moreover, the model highlights the importance of considering both supply and demand sides when analyzing gentrification. The specific results of the case study show the influence of the park in the formation of green gentrification
Feasibility and evolution studies on renewable energy communities in cities
Renewable energy communities could play a key role in the decarbonisation of the building stock, while providing important benefits to the members. This paper reviews the existing literature on this topic of growing scholarly interest. Three clusters have been identified, grouping the most common approaches to study feasibility analysis and the drivers that encourage individual participation. The paper also explores the role that different actors and forms of self-organisation might play in the development of these communities. The findings highlight a lack of homogeneity in the literature in conceptualising the benefits of renewable energy communities for different stakeholders. There is also evidence that little attention has been paid in the research to energy efficiency measures and the reduction of energy consumption. Financial costs and benefits are the main drivers, while environmental concerns and the desire to reduce dependence on energy-related uncertainties emerge as influential in community participation. Finally, a comparison of Italian case studies reveals a lack of comparability between studies due to discrepancies in the conceptualisation and calculation of indicators, such as the variation of self-sufficiency ratios ranging from 35.6 % to 83.8 % between reported and recalculated results. The insights gained from this study can help lay the ground for the establishment of a cross-sectorial approach to renewable energy community studies. A further important contribution of this work is to draw attention to the need for a common framework for assessing the performance of these communities. Finally, this study also usefully proposes clear calculation boundaries for the definition of indicators
Deep western boundary currents in the southwestern Pacific Ocean: WOCE PCM-9 : February 1991-December 1992
by R. Dale Pillsbury, D. Barstow, J. M. Bottero. G. Pittock, D. C. Root, J Simpkins III, R.E. Still and T. Whitworth III.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (page 7).National Science Foundation OCE-9002709.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Urban problems and patterns of change: The analysis of a downgraded industrial area in Turin
As it is well known, in Western countries cities are experiencing negative effects due to decentralization and deindustrialization, that have brought economic
crisis and urban decline. In order to contrast such decline, urban regeneration is getting more and more important in the current political agenda. In fact, urban regeneration means not only building-restoration operations, but also programs aiming at eliminating social decline, increasing the quality of life of the inhabitants, supporting the valorization of cultural resources, protecting the environmental system, bringing economic development, and so on. Urban regeneration looks at urban areas as complex and dynamic systems, in which different processes (physical, social, environmental and economic) drive the transition and the generation of important changes. This paper aims to reflect on urban problems and regeneration operations, focusing in particular on the role of evaluation tools for supporting decision-making in this context. Starting from the analysis of a real case study related to a critical area in the city of Turin, the article will propose different evaluation tools able to produce a complete picture of the problem and to define possible long-term visions for the
requalification of the site
Boosting Investments in Buildings Energy Retrofit: The Role of Incentives
More than 40% of the EU building stock was built before 1960 and 90% before 1990. It is common wisdom that older buildings typically exhibit greater energy demand than new ones. The renovation of existing buildings is therefore a cornerstone in the reduction of energy consumption and relative CO2 emissions under the post-carbon city paradigm.
In the present work, we analyze various energy retrofit strategies, evaluate their impact on buildings energy performance and determine their relative cost-benefit tradeoffs to address the multiple benefits of renovations and the financial barriers to their implementation and taking up.
Aim of the paper is to identify cost-effective energy retrofit strategies which match technological advancements and knowledge in energy retrofitting with environmental needs and end-user’s behavior. To determine how far (and how much) it is optimal to push on retrofitting of existing buildings, we investigate the role of incentives and their impacts on private investment decisions
Ranking of adaptive reuse strategies for abandoned industrial heritage in vulnerable contexts: A multiple criteria decision aiding approach
In recent years adaptive reuse has proven to be a promising strategy for preserving cultural heritage. When the adaptive reuse approach is used for cultural heritage, the expected outcome is not only the building protection, but the preservation of its historical and heritage significance, and the trade-off between the retention of symbolic values and the adaptation to new alternative (economically profitable) uses becomes of paramount importance. Decisions on the allocation of resources for cultural heritage preservation or development are based on a set of multiple, often conflicting, criteria, as well on the preferences of various, and not always consensual, stakeholders, who attribute different relative importance to market and non-market effects of adaptive reuse proposals. In this context, multiple criteria approaches provide a proper theoretical and methodological framework to address the complexity which characterizes adaptive reuse strategies of cultural heritage. This paper aims to contribute to this strand of literature by proposing a multicriteria decision aiding approach for ranking adaptive reuse strategies of cultural heritage. In detail, we present a novel application of the Preference Ranking Organization Method for Enrichment of Evaluations (PROMETHEE) to support the design and implementation of adaptive reuse strategies of abandoned industrial heritage in vulnerable contexts, and evaluate relative tangible and intangible effects. Industrial sites are frequently left to deteriorate, as their preservation is not considered as important as other kinds of heritage structures. Nevertheless, they are characterized by special architectural and technical features as well as by huge spaces suitable to be redeveloped for new uses. The paper focuses on the potential reuse of nine different abandoned buildings located in an industrial valley in the North-West of Italy, with a strong presence of wool and silk factories starting from the 18th century
A methodological framework for socio-economic impacts assessment of ict solutions to improve ieq, health and well-being
Mobistyle is a Horizon2020 European project that views the application at different demo cases
level of some personalized ICT solutions (Mobile App, Game and Dashboard) to drive persistent
behavioural changes in buildings occupants, leveraging on the three issues of energy, indoor
environmental quality, health and well-being.
Within the project two needs have been identified: i) assessing the effectiveness of the deployment
of Mobistyle solutions from both a private (owner/occupant) and a macro-economic (whole society)
point of view when multiple benefits are considered; ii) making the potential benefits tangible and
understandable for people in order to push a behavioral change. For both purposes, the Cost-Benefit
Analysis application turns to be useful.
Therefore, the aim of this paper is to present how a well-known economic evaluation tool, namely
the Cost-Benefit Analysis, have been applied to the Mobistyle project. A focus is given to the definition,
quantification and monetization of the impacts that the project can have in terms of well-being and
health.
The picture of the methodological framework, as well as some preliminary results on one of the
demo cases, are presented and discussed within this paper
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