14,114 research outputs found
Sir Christopher Booth in interview with Sir Gordon Wolstenholme
No full textSir Christopher Booth discusses a Yorkshire background, belated post-war service entry to medicine, training at St Andrew's and Dundee and early attachments to departments headed by Ian Hill and John McMichael. Subsequent work in McMichael's department at the Royal Postgraduate Medical School, Hammersmith, involves pioneering studies of vitamin B12 absorption with David Morland, leading to major interests in gastroenterology and a professorship in medicine at 'the Hammersmith'. That professorship and subsequent chairmanship of the School's Department of Medicine is reviewed, particularly the kinds of specialist short courses that evolved and an innovative widening of European links. In later stages of the interview Sir Christopher reflects on his directorship of the MRC Medical Research Centre at Northwick Park, Middlesex, the evolution of academic medicine in Britain and the administrative challenges of medical research. Finally he discusses interests in medical history, including the letters of John Fothergill
Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery
No full textCopyright @ 2014 Booth et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.When the nucleolus disassembles during open mitosis, many nucleolar proteins and RNAs associate with chromosomes, establishing a perichromosomal compartment coating the chromosome periphery. At present nothing is known about the function of this poorly characterised compartment. In this study, we report that the nucleolar protein Ki-67 is required for the assembly of the perichromosomal compartment in human cells. Ki-67 is a cell-cycle regulated protein phosphatase 1-binding protein that is involved in phospho-regulation of the nucleolar protein B23/nucleophosmin. Following siRNA depletion of Ki-67, NIFK, B23, nucleolin, and four novel chromosome periphery proteins all fail to associate with the periphery of human chromosomes. Correlative light and electron microscopy (CLEM) images suggest a near-complete loss of the entire perichromosomal compartment. Mitotic chromosome condensation and intrinsic structure appear normal in the absence of the perichromosomal compartment but significant differences in nucleolar reassembly and nuclear organisation are observed in post-mitotic cells
Interview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American City
No full textInterview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American Cit
Sir John Dacie FRS in interview with Sir Christopher Booth
No full textDistinguished haematologist Sir John Dacie FRS discusses the origins of his interests in haematology and an early appointment at the Royal Postgraduate Medical School, Hammersmith, with Dr Janet Vaughan (also a contributor to this archive). Following this experience, he returned to King's College Hospital where he had trained and with the beginning of World War II became a blood transfusion officer with the opportunity to establish a central pathology laboratory where his research continued. Army blood transfusion service draftings in Normandy, then Holland, followed, with opportunities to investigate various aspects of blood loss in battle casualties, particularly to conduct cell survival studies.
Discussion then concentrates on Professor Dacie's career at the Royal Postgraduate Medical School, particularly the creation of a Department of Haematology and studies of atypical hereditary haemolytic anaemias, haemophilia and sideroblastic anaemia. Conversation then turns to his pioneering editorship of the British Journal of Haematology and his classical contributions to the haematology literature. Finally he reflects on a life-long interest in natural history, especially butterflies
Dr Stephen Lock in interview with Sir Christopher Booth
No full textDr Stephen Lock, a former editor of the British Medical Journal, 1975-90, discusses his family background, early studies, entry to medicine, first clinical appointments, disillusionment and uneasy transition to a career in medical journalism. His recollections of medical school life, house and registrar appointments provide a critical dissection of established hospital practice in the 1940s and 1950s and a number of senior clinicians. Similarly forthright is discussion of early attachments to The Lancet and BMJ, especially the editors under whom he worked, Sir Theodore Fox and Hugh Clegg. The major challenges and hazards of medical journalism are then considered in some depth, including such issues as editorial pressures, peer review and libel. There follows an account of the founding of the 'Vancouver group' of medical editors, set up to assist standards. In a final section the interview turns to such issues as journalistic campaigning, problems of confidentiality and plagiarism
Matt Christopher Papers - Accession 1309
No full textThe collection includes letters written by the children’s book author, Matt Christopher, to his son, Marty Christopher. Many of the letters also contain newspaper articles of interest to Matt Christopher, which deal with local sports teams, his writing career, his participation in an exhibition baseball game against the New York Giants in 1938, and other of general interest. Most of the letters are personal in nature, however, a majority of the letters delve into Matt Christopher’s writing career, personal interests, the author’s health, as well as his family life.https://digitalcommons.winthrop.edu/manuscriptcollection_findingaids/2649/thumbnail.jp
Matt Christopher Papers - Accession 1221
No full textMatt Christopher (1917-1997) was a prolific author of children’s books having written over 100 books as well as over 300 short stories, articles, poems, and screenplays. Most of his writings dealt with sports themes, but he also wrote fantasy and mystery themed stories as well. The Matt Christopher Papers consist of both published and unpublished manuscripts, articles, and short stories. Also included are personal and business correspondence, biographical information, scrapbooks, photographs, and memorabilia.https://digitalcommons.winthrop.edu/manuscriptcollection_findingaids/1976/thumbnail.jp
Dr. Christopher von Rueden – Faculty Author Interview
No full textDr. Christopher von Rueden, an anthropologist and Assistant Professor in the Jepson School of Leadership Studies, discusses a recent article entitled, “Men’s status and reproductive success in 33 non-industrial societies: Effects of subsistence, marriage system, and reproductive strategy,” which he co-authored with Dr. Adrian Jaeggi, an anthropologist at Emory University. Their findings were recently published in the journal, Proceedings of the National Academy of Sciences
ESP Across Cultures
No full textThis present volume constitutes the third online edition of ESP Across Cultures.
The decision to change from a paper-based to an online edition has undoubtedly
been beneficial in terms of enjoying greater visibility within the international academic
community. One thing that has not changed over the years, however, since
the inception of the journal in 2004, has been the policy of double-blind peer reviewing,
which means that only a selected number of the papers submitted end up as
being published.
There are seven papers in the current issue, each one analysing a particular aspect
of English for Specific Purposes from a cross-cultural perspective.
The first paper, by Hmoud S. Alotaibi, focuses on research article introductions
in Arabic, analysing the extent to which scholars writing in Arabic in the sphere of
education adhere to the CARS (Create A Research Space) model delineated by John
Swales which was elaborated in particular with regard to the academic conventions
widely adopted in the English-speaking world. Instead of restricting the investigation
to the introductory section as past studies in this field did, the author examines
all of the subheadings and he concludes that all introductions include Move 2 in a
subheading entitled the Problem of the Study, a result that contradicts previous
findings where the paucity of Move 2 was common in non-English RAs, and especially
in Arabic ones.
Patrizia Anesa analyses the websites of the main arbitration centres operating in
Asia from a textual perspective to define how they are discursively constructed and
can be used as promotional tools, thereby helping us to evaluate the importance assumed
by internationalization processes or by local cultural elements in promoting a
particular centre as a seat for international arbitration. She concludes that while
some scholars argue that we are witnessing the ‘Asianization’ of arbitration, with
the increasing bargaining power of Asian parties, on the other hand a phenomenon
of ‘Universal Arbitration’ is also emerging, i.e. a form of convergence of how disputes
are resolved so that parties of any nationality can operate in the same way
with ever fewer language barriers.
In their paper, Mahmood Reza Atai and Fatemeh Asadnia examine the communicative
and promotional function of university homepages by looking at the ‘university
overview’, ‘university mission statement’, and ‘university introduction at a
glance’ genres, using a corpus of 210 texts selected from homepages of the top 500
universities ranked by the Academic Ranking of World Universities. The findings
demonstrated that the three genres shared communicative purposes, functional
units, certain moves and steps, socio-academic contexts, and discourse community
members that led to the formation of a genre set.
Gaetano Falco explores ways of using comics in an MA course on translation of
economic texts as a means of stimulating the interest of language students with no
economics skills in order to introduce economics-related lexis and improve thematic
competence in general. He observes that empirical research has shown that films
and comics can indeed be useful resources to teach economic translation to students
with no skills in economics. However, the author warns that the use of comics for
educational purposes may have its drawbacks, e.g. when students deal with complex
sign systems which embody complex economic concepts, where often the humorous
element is lost.
In her paper, Irina Khoutyz describes the differences in how scholars present
their findings in research articles (RA) in international journals in English and in
Beyza Björkman
Christian Burgers
Jan Chovanec
Anda-Elena Cretiu
Erika Dalan
John Douthwaite
Hanem El-Farahaty
Said Faiq
Silvia Ferreri
Inmaculada Fortanet-Gómez
Pedro Fuertes-Olivera
Giuliana Garzone
Christoph Hafner
Ruba Khamam
Anna Loiacono
Geraldine Ludbrook
John McRae
Susan Petrilli
Silvia Pireddu
Tarja Salmi-Tolonen
Jeffrey Segrave
Charlotte Taylor
Margherita Ulrych
John Kenneth White
Jessica Williams
I hope you will enjoy the current issue of this journal and will make the most of
the free access to all past issues.
Christopher Williams
(Chief Editor)
6 FOREWORD
local journals in Russian. She then looks into the reasons for these differences, seeking
explanations from the sociocultural contexts in which these RAs were written,
as well as providing advice to local authors as to how to make their RAs more competitive
at the international level. The differences include the apparent lack of
structure of Russian RAs with respect to English RAs; the tendency in Russian authors
not to specify the purpose in writing a paper; and the tendency of Russian authors
to present the methodology used in less detail compared with English RAs.
Luisella Leonzini investigates the use of verbal and visual metaphors in economic-
media discourse within the context of the euro crisis by studying the correlation
between linguistic and pictorial metaphors and text-image intersemiotic relations.
The research is based on a cross-analysis of English and Italian editorial
articles published between 2009 and 2012. In both corpora, metaphorical realizations
frame the economic crisis which hit the single currency and the eurozone in
2009 as a partial collapse and hint at a possible return to stability in the form of a
recovery. The aim of this paper is to analyse the collapse/caduta and
recovery/ripresa metaphors across languages in the press.
Ian Robinson reports on using corpus linguistics to aid students in writing a creative
text. He looks at the available literature to help understand what is meant by
‘creativity’. A worksheet was prepared using a corpus linguistic analysis of modern,
English versions of the stories of the Brothers Grimm. This worksheet was constructed
with the use of a specialized corpus, and a stop-list was created which contained
single words as well as word clusters found in the tales. Students were then
asked to select some of these words and phrases to help them write stories which
were then analysed, and a follow-up questionnaire was used to elicit the students’
perceptions concerning creativity. The author concludes that creativity is essential
in EFL and that it is something to be fostered in students
ICONS II: Identifying Continence OptioNs after Stroke randomised controlled trial
No full textLois Thomas, Christine Roffe, Joanne Booth, Christopher Chapple, Caroline Watkins, Brenda Roe, Christopher Sutton, Bruce Hollingsworth, Céu Mateus, David Britt, Cliff Panton and Kina Bennett; for the MRC Continence Programme and R&D Stroke and Incontinence Stud
- …
