102,271 research outputs found
Canadian industry in 1871 project (CANIND71), University of Guelph, Ontario, 1982 - 2008
No full textThe Canadian Industry in 1871 project involved digitizing the manuscript schedules of the 1871 Census of Canada, the only detailed industrial census returns to survive so completely from the past. The database includes more than 45,000 industrial establishments, each with up to 100 variables, including many that never appeared in the published census reports. This resource provides uniquely valuable snapshots of industrial activity just after Confederation, at a time of transition in technology, business organization and work discipline.
As part of the project, a website was developed to provide access to the CANIND71 database, including an online search interface and a detailed user guide. The search tool was a SAS application that dynamically returned records from the underlying CANIND71 database in response to queries from links on pages within the website, and from user-customizable queries submitted via a search tool on the website.
As of 2021, the CANIND71 website and online search tool were decommissioned. The database and supplementary materials are now available through the University of Guelph Research Data Repositories.</p
Trace-strength and source-monitoring accounts of accuracy and metacognitive resolution in the misinformation paradigm
No full textTwo experiments are reported that investigate the impact of misinformation on memory accuracy and metacognitive resolution. In Experiment 1, participants viewed a series of photographs depicting a crime scene, were exposed to misinformation that contradicted details in the slides, and later took a recognition memory test. For each answer, participants were required to indicate whether they were willing to testify (report) their answer to the Court and to rate confidence. Misinformation impaired memory accuracy but it had no effect on resolution, regardless of whether resolution was indexed with confidence-rating measures (gamma correlation and mean confidence) or a report-option measure (type-2 discrimination: d’). In Experiment 2, a similar accuracy-confidence dissociation was found, and the misinformation effect occurred mostly with fine-grained responses, suggesting that responding was based on recollected details. We argue that the results support source-monitoring accounts of accuracy and resolution rather than accounts based on trace strength
An altered 11-kilobase transcript in leukemic cell lines with the t(4;11)(q21;q23) chromosome translocation.
No full textThe 11q23 chromosome band is frequently associated with chromosomal aberrations in human leukemias. We have previously cloned a DNA fragment derived from chromosome 11 which could be used as a probe to detect rearrangements in DNAs from the leukemic cells of patients with the t(4;11), t(9;11), and t(11;19) translocations. In this study we now show that the same probe detects DNA rearrangements in malignant cells from patients with the t(1;11), t(6;11), t(10;11), and del (11q23) chromosomal abnormalities. A second probe obtained from a region located centrometric to the breakpoint cluster detects major and minor transcripts of 12.5 and 11.5 kilobases, respectively, in all cell lines examined. The same probe identifies an altered 11-kilobase RNA in all three independent cell lines with the t(4;11)(q21;q23) chromosome translocatio
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
MOPOD: a generic model of porosity development
No full textA code, MOPOD, has been developed to investigate general relationships between simple porosity growth laws and pore growth phenomena. MOPOD has been formulated as an ‘initial value problem’ and to date, investigations have focused on a very simple porosity growth law of the form dai(t)/dt= vei, where e is the aperture growth rate exponent. A range of qualitatively distinct evolved geometries have been described for porosity growth on 2D and 3D arrays of varying geometries and connectivities as a function of the exponent, e, of the aperture growth-rate law, and the width of the initial aperture distribution, z. At low growth-rate exponents and moderate values of z over time there is a homogenization of apertures oriented sub-parallel to the head gradient. At moderate growth-rate exponents these apertures become increasingly heterogeneous in evolved arrays, with planar heterogeneities developing sub-parallel to the head gradient for low values of z while anastomosing structures develop at higher values of z. For larger growth-rate exponents preferentially enlarged array-spanning paths develop. No selforganization
phenomena have been observed because periodic or cyclic behaviour is not inherent in the simple growth laws investigated to date
School gardens and cultivating learning
No full textA strong positive link has been established between children’s learning and out of class activities (Bloomfield, P. 2000 & 2001; Humphries, S., Rowe, S. 2004; Palmer J, 1998). In this paper we aim to bring together key concepts from both Education for Sustainable Development (ESD) and Global Citizenship (GC) through a child’s experience of learning through growing plants in a range of settings and contexts. These include examples from British Early Years settings to ITE and African case studies. The paper argues for greater emphasis of school gardening in ITE and illustrates a selection of ways forward and work in progress
School gardens and cultivating learning
No full textA strong positive link has been established between children’s learning and out of class activities (Bloomfield, P. 2000 & 2001; Humphries, S., Rowe, S. 2004; Palmer J, 1998). In this paper we aim to bring together key concepts from both Education for Sustainable Development (ESD) and Global Citizenship (GC) through a child’s experience of learning through growing plants in a range of settings and contexts. These include examples from British Early Years settings to ITE and African case studies. The paper argues for greater emphasis of school gardening in ITE and illustrates a selection of ways forward and work in progress
The poems of Robert Bloomfield.
No full textEdited by T. Park.v. 1 The farmer's boy and Good tidings.--v. 2. Rural tales and Wild flowers.--v. 3. Banks of Wye and May-day with the muses.Mode of access: Internet
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
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