343 research outputs found
Effect of chronic hypoxia on leptin, insulin, adiponectin, and ghrelin
No full textThe endocrine system plays an important role in the adaptation to hypoxia. The aim of this study was to assess the effect of chronic hypoxia on insulin, adiponectin, leptin, and ghrelin levels in a neonatal animal model. Sprague-Dawley rats were placed in a normobaric hypoxic environment at birth. Controls remained in room air. Rats were killed at 2 and 8 weeks of life. Insulin, adiponectin, leptin, and ghrelin were measured. At 2 weeks of life, there was no significant difference in insulin, adiponectin, and leptin levels between the hypoxic and control rats. The only statistically significant difference was found in ghrelin levels, which were lower in the hypoxic group (3.19 ± 3.35 vs 24.52 ± 5.09 pg-mL; P .05). At 8 weeks of life, insulin was significantly higher in the hypoxic group (0.72 ± 0.14 vs 0.44 ± 0.26 ng-mL; P .05) and adiponectin was significantly lower (1257.5 ± 789.5 vs 7817.3 ± 8453.7 ng-mL; P .05). Leptin and ghrelin did not show significant difference in this age group, but leptin level per body weight was higher in the hypoxic group. Finally, we conclude that 2 weeks of continuous neonatal hypoxic exposure leads to a decrease in plasma ghrelin only with no significant change in insulin, adiponectin, and leptin and that 8 weeks of hypoxia leads to a decrease in adiponectin with an increase in insulin despite a significant decrease in weight. © 2008 Elsevier Inc. All rights reserved.Ambrosini G, 2002, J BIOL CHEM, V277, P34601, DOI 10.1074-jbc.M205172200; BAUM D, 1969, J CLIN ENDOCR METAB, V29, P991; BAUM D, 1976, ENDOCRINOLOGY, V98, P359; Bennett BD, 1996, CURR BIOL, V6, P1170, DOI 10.1016-S0960-9822(02)70684-2; Bitar FF, 2002, PEDIATR RES, V51, P144, DOI 10.1203-00006450-200202000-00005; BITAR FF, 1994, J SURG RES, V57, P264, DOI 10.1006-jsre.1994.1142; Bornstein SR, 1998, J CLIN ENDOCR METAB, V83, P280, DOI 10.1210-jc.83.1.280; Braun B, 2001, J APPL PHYSIOL, V91, P623; Considine RV, 1996, NEW ENGL J MED, V334, P292, DOI 10.1056-NEJM199602013340503; Dagogo-Jack S, 1998, KIDNEY INT, V54, P997, DOI 10.1046-j.1523-1755.1998.00077.x; GALLON V, 1972, ENDOCRINOLOGY, V91, P1393; GARVEY D, 1979, J ENDOCRINOL, V80, P333, DOI 10.1677-joe.0.0800333; GOSNEY J, 1991, INT J BIOMETEOROL, V35, P1, DOI 10.1007-BF01040955; GOSNEY JR, 1986, J ENDOCRINOL, V109, P119, DOI 10.1677-joe.0.1090119; Grosfeld A, 2002, DIABETOLOGIA, V45, P527, DOI 10.1007-s00125-002-0804-y; HEALTH D, 1981, ENDOCRINES MAN HIGH, P250; HERMANS RHM, 1994, PHYSIOL BEHAV, V55, P469, DOI 10.1016-0031-9384(94)90102-3; JACOBS R, 1988, J DEV PHYSIOL, V10, P97; Kershaw EE, 2004, J CLIN ENDOCR METAB, V89, P2548, DOI 10.1210-jc.2004-0395; Larsen JJ, 1997, J PHYSIOL-LONDON, V504, P241, DOI 10.1111-j.1469-7793.1997.241bf.x; Meissner U, 2003, BIOCHEM BIOPH RES CO, V303, P707, DOI 10.1016-S0006-291X(03)00401-7; Mise H, 1998, J CLIN ENDOCR METAB, V83, P3225, DOI 10.1210-jc.83.9.3225; MORDES JP, 1983, NEW ENGL J MED, V308, P1135, DOI 10.1056-NEJM198305123081906; Raff H, 2001, HORM METAB RES, V33, P151, DOI 10.1055-s-2001-14929; Raff H, 2003, ENDOCRINE, V21, P159, DOI 10.1385-ENDO:21:2:159; Sagawa N, 2002, PLACENTA, V23, pS80, DOI 10.1053-plac.2002.0814; Tillmar L, 2002, MOL MED, V8, P263; Tschop M, 2001, ADV EXP MED BIOL, V502, P237; Tschop M, 1998, LANCET, V352, P1119, DOI 10.1016-S0140-6736(05)79760-9; Westerterp KR, 2001, NEWS PHYSIOL SCI, V16, P134; Wolk R, 2005, OBES RES, V13, P186, DOI 10.1038-oby.2005.24; Yasumasu T, 2002, OBES RES, V10, P128, DOI 10.1038-oby.2002.20; Yasumasu T, 2002, OBES RES, V10, P857, DOI 10.1038-oby.2002.117; ZAYOUR D, 2003, ENDOCR RES, V29, P9116111
12 Mistaken Claims about F.F. Bosworth
No full textCopyright © 2018 by Roscoe Barnes III
#FFBosworthThis blog post focuses on 12 of the most common misconceptions that people have about F.F. Bosworth, author of Christ the Healer. Its aim is to provide insight into his life history. The information is presented with the intent of bringing clarity and corrections to some of the mistaken ideas that people have about his life and ministry. The author suggests that while much is being written about Bosworth, some of the published material cannot be trusted because of faulty research.For more information on F.F. Bosworth, follow the Bosworth
Matters blog at: http://ffbosworth.strikingly.com#ChristTheHealer #BosworthMatters #BosworthMention</p
Regulation of the sphingolipid signaling pathways in the growing and hypoxic rat heart
No full textSphingolipids (SLs) have a biomodulatory role in physiological as well as pathological cardiovascular conditions. This study aims to assess the variation of SL mediators and metabolizing enzymes in the growing and hypoxic rat heart. Sprague-Dawley rats were placed in a hypoxic environment at birth. Control animals remained in room air. In control animals, activities of acidic-sphingomyelinase (A-SMase), sphingomyelin synthase (SMS), glucosylceramide synthase (GCS), and ceramidase decreased with age in both ventricles whereas activity of neutral-sphingomyelinase (N-SMase) increased with age. Hypoxic RV mass was 171 and 229percent that of controls, at 4 and 8 weeks, respectively. This was accompanied by an increase in RV myocardial ceramide synthesis, consumption and breakdown, with a net effect of suppression of ceramide accumulation and increase in diacylglycerol (DAG) concentration. In addition, significant increase in activities of: A-SMase by 26 and 29percent, SMS by 108 and 40percent, and ceramidase by 66 and 35percent, in the hypoxic RV rats as compared to controls, was noted at 4 and 8 weeks of age, respectively. Sphingolipids and their regulating enzymes appear to play a role in adaptive responses to chronic hypoxia in the neonatal rat heart. © 2005 Elsevier Inc. All rights reserved.AMES BN, 1960, J BIOL CHEM, V235, P769; Bielawska A, 1996, J BIOL CHEM, V271, P12646; Bitar FF, 2002, PEDIATR RES, V51, P144, DOI 10.1203-00006450-200202000-00005; BITAR FF, 1994, J SURG RES, V57, P264, DOI 10.1006-jsre.1994.1142; BLIGH EG, 1959, CAN J BIOCHEM PHYS, V37, P911; Dbaibo GS, 1998, APOPTOSIS, V3, P317, DOI 10.1023-A:1009668802718; De Maria R., 1997, SCIENCE, V277, P1652; EXTON JH, 1994, BBA-LIPID LIPID MET, V1212, P26, DOI 10.1016-0005-2760(94)90186-4; FOLCH J, 1957, J BIOL CHEM, V226, P497; Hannun YA, 1996, SCIENCE, V274, P1855, DOI 10.1126-science.274.5294.1855; Hernandez OM, 2000, CIRC RES, V86, P198; KAJSTURA J, 1995, EXP CELL RES, V219, P110, DOI 10.1006-excr.1995.1211; Liliom K, 2001, BIOCHEM J, V355, P189, DOI 10.1042-0264-6021:3550189; Luberto C, 1998, J BIOL CHEM, V273, P14550, DOI 10.1074-jbc.273.23.14550; Moravec M, 2002, BASIC RES CARDIOL, V97, P153, DOI 10.1007-s003950200006; O'Brien NW, 2003, CIRC RES, V92, P589, DOI 10.1161-01.RES.0000066290.29715.67; Olivera A, 2000, METHOD ENZYMOL, V311, P215; PREISS J, 1986, J BIOL CHEM, V261, P8597; Rudolph AM, 1999, PEDIATR RES, V46, P141, DOI 10.1203-00006450-199908000-00002; SIAKOTOS AN, 1969, LIPIDS, V4, P239, DOI 10.1007-BF02532639; Spiegel S, 2002, J BIOL CHEM, V277, P25851, DOI 10.1074-jbc.R200007200; VANVELDHOVEN PP, 1989, ANAL BIOCHEM, V183, P177, DOI 10.1016-0003-2697(89)90186-3; YAVIN E, 1969, BIOCHEMISTRY-US, V8, P1692, DOI 10.1021-bi00832a052; Zayour D, 2003, ENDOCR RES, V29, P191, DOI 10.1081-ERC-120022301; Zhang DX, 2001, BASIC RES CARDIOL, V96, P267, DOI 10.1007-s00395017005797
New Hashtags for F.F. Bosworth
No full textCopyright (c) 2018 by Roscoe Barnes III#FFBosworthThis is an announcement about the author's use of #BosworthMatters and #BosworthMention to share his research on F.F. Bosworth, author of Christ the Healer.For more information on Bosworth, follow the Bosworth Matters blog at ffbosworth.strikingly.com</div
F.F. Bosworth's Advice to A.W. Tozer
No full textCopyright (c) 2018 by Roscoe Barnes III#FFBosworthI have argued for over a decade that F.F. Bosworth matters, and he matters in a significant way, especially in Pentecostal Church History. This article shows how Bosworth's influence extended to church leaders outside the Pentecostal tradition. Using Lyle Dorsett's book as a reference, it presents Bosworth's advice to a young A.W. Tozer, who would go on to become a famous author of deeper life books. Both men were members of the Christian and Missionary Alliance. Bosworth spoke to Tozer about the ministry of healing and speaking in tongues.NOTE: For more information on F.F. Bosworth, please visit: http://ffbosworth.strikingly.comFor a closer look at Bosworth's counsel to Tozer, see A Passion for God: The Spiritual Journey of A.W. Tozer by Lyle Dorsett (Moody Publishers, 2008)#ChristTheHealer</div
The Passing of Eugene Peterson and F.F. Bosworth: A Look at Their Transition and 'Ultimate Triumph'
No full textCopyright © 2018 by Roscoe
Barnes III
#FFBosworth
#EugenePeterson
In this blog post, the
writer discusses the passing of Eugene Peterson and F.F. Bosworth and how they
both had conversations with their deceased loved ones as they were dying. The
author suggests there are remarkable similarities in their final moments. He also
notes the experiences of Peterson and Bosworth are not uncommon in church
history.
For more information on
F.F. Bosworth, follow the Bosworth Matters blog at:
http://ffbosworth.strikingly.com.
#ChristTheHealer
#BosworthMatters #BosworthMention
</p
Upcoming Post: Similarities in the Prison-Themed Messages of Kenneth W. Hagin and F.F. Bosworth
No full textCopyright © 2018 by Roscoe Barnes III
#FFBosworthThis blog post is as an
announcement of a forthcoming post/article on the writings of Kenneth W. Hagin and
F.F. Bosworth. The author suggests that Hagin’s minibook, The Prison Door is Open: What Are You Still Doing Inside?, seems to
borrow from Bosworth’s article, "The Opening of the Prison," without
proper attribution.For more information on F.F. Bosworth, follow the Bosworth
Matters blog at: http://ffbosworth.strikingly.com#ChristTheHealer #BosworthMatters #BosworthMention</p
COL F.F. PIENAAR'S BOER WAR DIARY (PART I)
No full textIn 1902, Filip Pienaar, a young Boer officer in exile at the Monastery of Tomar in Portugal, recorded his Boer war experiences. These were published by Methuen in 1902, under the title With Steyn and De Wet, The book was banned one month after publication, The author, Lt Col F.F. Pienaar, later joined the Union Defence Force, served in the German South West Africa Campaign and later became South Africa's first ambassador to Portugal in 1939, from where he also conducted correspondence with his cousin General Dan Pienaar. As a son-in-law of the late F.F. Pienaar, it is my privilege to reproduce part of his Boer War experiences. Pienaar's account is one of the first books on the Boer War and covers several eye-witness accounts at that time.</p
Réévaluation des arguments en faveur de l'existence d'une profession dentaire au troisième millénaire avant J.C. en Egypte
No full textThree facts have been used to assess that an organised profession of dentist existed in Egypt during the 3rd millennium B.C. The author after having discussed concludes that this statement is inacceptable.Trois arguments ont été avancés en faveur de l'existence en Egypte d'une profession dentaire au troisième millénaire av. J.-C. ; l'auteur les examine à nouveau tous les trois et les élimine l'un après l'autre.Leek F.F. Réévaluation des arguments en faveur de l'existence d'une profession dentaire au troisième millénaire avant J.C. en Egypte. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, XIII° Série. Tome 8 fascicule 3, 1981. pp. 377-380
F.F. Bosworth Mentioned in G.J. Hocking’s book, 'The Pentecostal Paradox': The author discusses hard questions about the Pentecostal movement
No full textCopyright (c) 2019 by Roscoe Barnes III#FFBosworthThis blog post presents a discussion of F.F. Bosworth and
his position on evidential tongues during the early days of the Assemblies of
God. The writer notes: “In the section of the book that mentions Bosworth, Hocking
writes about the evangelist’s position on speaking in tongues. He notes the
historic moment in 1918 when Bosworth resigned from the Assemblies of God over
the issue of evidential tongues.”Note: For more information on F.F. Bosworth, follow the Bosworth Matters blog at ffbosworth.strikingly.com#ChristTheHealer #BosworthMatters</div
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