267 research outputs found
On the role of the helicity in the energy transfer in three-dimensional turbulence
No full textBehavior of the turbulent flows could be changed by changing the nature of the external force or the confining geometry which essentially results in breaking some of the symmetries of the ideal homogeneous and isotropic flows. In a numerical simulation, however, it is possible to selectively break symmetries of the Navier-Stokes equations with other constraints like helicity. In a recent [1] simulation of a decimated version of the incompressible three dimensional Navier-Stokes equations, where helicity was maintained sign-definite using a helical projection, a reversal of energy cascade similar to two-dimensional Navier-Stokes equations was observed. The sign- definite helicity breaks the parity symmetry of the flow. It is one of the important symmetries of the flow that contributes to the forward energy cascade in three dimensional Navier-Stokes equations. In our study we measure the degree to which the parity symmetry controls the direction of the cascade. We introduce a mechanism in which the parity is broken stochastically but in a time frozen manner with helical constraints. We keep triadic interactions in Fourier space involving modes with definite sign of helicity and decimate the triads of other modes with opposite sign of helicity with a fixed probability. We studied the cascade of energy in three dimensional turbulence by changing the relative weight between positive and negative helicity modes. We present the results from our recent simulations
Executive health checkup package at All India Institute of Medical Sciences, Bhubaneswar: A novel approach
No full textEarly detectionof a disease leads to relatively simple courses of treatment and prevents life-threatening complications. Many health conditions can be corrected or maybe improved through treatment modalities if they are discovered by health screening facilities. Health screening program such as executive health checkup is convenient, affordable, inexpensive, and vastly beneficial for the patients. Hence, health screening saves lives immensely by early detection of diseases and preventing serious complications. It is an effective component of healthcare. It achieves more positive effects than medical treatment and at a lower cost. Health promotion is aimed at influencing people's social circumstances and lifestyles so that their health is improved (or maintained) and disease is prevented
Real-space Manifestations of Bottlenecks in Turbulence Spectra
No full textAn energy-spectrum bottleneck, a bump in the turbulence spectrum between the inertial and dissipation ranges, is shown to occur in the non-turbulent, one-dimensional, hyperviscous Burgers equation and found to be the Fourier-space signature of oscillations in the real-space velocity, which are explained by boundary-layer-expansion techniques. Pseudospectral simulations are used to show that such oscillations occur in velocity correlation functions in one- and three-dimensional hyperviscous hydrodynamical equations that display genuine turbulence
Essays on the Indian Economy: Competitive Pressure, Productivity and Performance.
No full textIndia undertook a drastic economic reform program in 1991, with the significant objectives of removing existing inefficiencies and enhancing global competitiveness. A competitive environment is a prerequisite condition for gaining higher productivity. The main desired role of economic liberalization is to enhance the efficient utilization of inputs with relaxing constraints input use and technology choices and gains from international trade by bringing global competitive pressure to the economy. The dissertation proposes a macro productivity-efficiency analysis while taking care of the inter-linkages in the economy. This is extended to address to a few important issues of the Indian economy, viz. income distribution, poverty, wage inequality between skilled and unskilled labour, returns to education and performance of formal and informal sectors. These above-mentioned issues are captured with the help of three independent essays. The analytical tool is based on a general equilibrium-activity analysis where welfare maximization subject to input and trade constraints results in competitive equilibrium. Competitive input prices reflect factor productivity. Incorporation of input-output framework captures the inter-sectoral linkages. The social accounting matrix (SAM), which plays an important role in establishing inter-linkages in the economy by combining input-output analysis and household income distribution, provides the basic data set for our model.
G-Drazin inverse combined with inner inverse
No full text[EN] This article introduces new classes of generalized inverses for square matrices named GD1, and the dual, called 1GD inverse. In addition, we discuss a few characterizations and representations of these inverses. The explicit expressions of these inverses have been established via core-nilpotent decomposition. Further, we introduce a binary relation for GD1 inverse and 1GD inverse, along with a few derived properties.The second author is partially supported by the Science & Engineering Research Board (SERB),Govt. of India [grant ID SUR/2022/004357]. The third author was partially supported by the Universidad Nacional de Rio Cuarto [grant PPI 18/C559], Universidad Nacional de La Pampa, Facultadde Ingenieria [grant resol. nro. 135/19], Universidad Nacional del Sur [grant PGI 24/L108], and Ministerio de Economia, Industria y Competitividad (Spain) [grant red de excelencia RED2022-134176-T].Maharana, G.; Sahoo, JK.; Thome, N. (2024). G-Drazin inverse combined with inner inverse. Linear and Multilinear Algebra. https://doi.org/10.1080/03081087.2024.2316786
Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts.
No full textCopyright: 2013 Hermann et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.PURPOSE: In spite of intense research efforts, pancreatic ductal adenocarcinoma remains one of the most deadly malignancies in the world. We and others have previously identified a subpopulation of pancreatic cancer stem cells within the tumor as a critical therapeutic target and additionally shown that the tumor stroma represents not only a restrictive barrier for successful drug delivery, but also serves as a paracrine niche for cancer stem cells. Therefore, we embarked on a large-scale investigation on the effects of combining chemotherapy, hedgehog pathway inhibition, and mTOR inhibition in a preclinical mouse model of pancreatic cancer. EXPERIMENTAL DESIGN: Prospective and randomized testing in a set of almost 200 subcutaneous and orthotopic implanted whole-tissue primary human tumor xenografts. RESULTS: The combined targeting of highly chemoresistant cancer stem cells as well as their more differentiated progenies, together with abrogation of the tumor microenvironment by targeting the stroma and enhancing tissue penetration of the chemotherapeutic agent translated into significantly prolonged survival in preclinical models of human pancreatic cancer. Most pronounced therapeutic effects were observed in gemcitabine-resistant patient-derived tumors. Intriguingly, the proposed triple therapy approach could be further enhanced by using a PEGylated formulation of gemcitabine, which significantly increased its bioavailability and tissue penetration, resulting in a further improved overall outcome. CONCLUSIONS: This multimodal therapeutic strategy should be further explored in the clinical setting as its success may eventually improve the poor prognosis of patients with pancreatic ductal adenocarcinoma
EDTA functionalized magnetic nanoparticle as a multifunctional adsorbent for Congo red dye from contaminated water
No full textEffect of surfactant concentration on the ultraviolet sensing properties of ZnO-cellulose nanocomposites
No full textEffect of annealing temperature on physical properties of solution processed nickel oxide thin films
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