1,720,995 research outputs found
Evaluation the anti-ageing and repair activity of plant stem cell extract in a topical formulation
No full textTopical pimecrolimus in the treatment of genital lichen Sclerosu
No full textPimecrolimus is a drug belonging to the class of macrolactamic immunosuppressants, similar to tacrolimus, and has been employed mainly in the treatment of atopic dermatitis, but is also active in other skin diseases, including genital lichen sclerosus (LS). The safety profile of pimecrolimus was the subject of special attention by the US FDA, which in 2005 issued a Public Health Advisory on the potential risk of cancer associated with the use of topical calcineurin inhibitors. However, many scientific societies have criticized the FDA note, referring to the vast literature on the subject in which there is no evidence available that topical use of the drug is dangerous. Patients with LS, of both sexes, may develop genital squamous cell carcinoma. This event, however, is not a contraindication to the use of pimecrolimus
Inosiplex in treatment of papilloma-virus lesion: A first report [Il Metisoprinolo (viruxan) nel trattamento delle lesioni da Papilloma Virus. Primi risultati]
No full textKaposi's sarcoma after cortisone treatment in a case of pemphigoid [Malattia di Kaposi insorta dopo trattamento steroideo in soggetto affetto da pemfigoide]
No full textClassification and pathophysiology of skin grafts
No full textFlaps and grafts are the 2 main surgical procedures to repair losses of skin tissue, A flap is a full-thickness portion of skin sectioned and isolated peripherally and in depth from (lie surrounding skin, except along one side, called the peduncle. A graft is a section of skin, of variable thickness and size, completely detached from its original site and moved to cover the zone to be repaired. According to their thickness, skin grafts are classified as split thickness (or partial) and full thickness, The former is further divided into thin, intermediate and thick. Split-thickness skin grafts usually take well, whereas a full-thickness graft only takes if it is relatively small. Grafts are,list) divided. on the basis of their origin, into the following: autografts, when the donor and recipient are the same individual; homografts, when the donor and recipient are different subjects belonging to the same species-, hetero- or xenografts, when the donor and recipient belong to different species, Only autografts can take, whereas homo- and heterografts are rejected, Homo- and heterografts, however, can be useful in particular conditions, for example, extensive burns. because they temporarily ensure vital skin functions. (c) 2005 Elsevier Inc. All rights reserved
Erosive lichen planus and post-hepatitis cirrhosis [Lichen erosivo associato a cirrosi post-epatitica]
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Bullous congenital ichthyosiform erythroderma in a mother and son
No full textThe occurrence of two cases of bullous congenital ichtyosiform erythroderma (BCIE) in a mother and son is reported. Clinical diagnosis was confirmed by histological and ultrastructural findings, which demonstrated marked changes in the cytoskeleton of the keratinocytes of the Malpighian layer and areas of cytolysis and hypoplasia of the tonofilament-hemidesmosome complexes in the cells of the granulous layer. These results and the possible aetiopathogenic mechanisms are discussed in the light of the most recent data in the literature. Treatment with oral etretinate proved to be helpful, but not long lasting
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