1,721,459 research outputs found
Abilitazione Scientifica Nazionale - Professore I Fascia- Bando 2012 (DD n. 222/2012)
No full textNON E' UNA PUBBLICAZIONE- ABILITAZIONE SCIENTIFICA NAZIONALE - PROFESSORE I FASCIA- MED06D4- gastroenterologi
C1q-binding donor-specific antibody assays help define risk and prognosis in antibody-mediated rejection
No full textAntibody-mediated rejection represents the first cause of graft loss in renal transplant recipients, and it is imperative to identify appropriate tools to enable risk stratification of such patients. Lately, the usefulness of measuring complement-binding anti–human leukocyte antigen (HLA) donor-specific antibodies (DSAs) in renal transplantation has been intensely debated. While the jury is still out, recent data suggest that monitoring complement-binding DSAs may help to recognize high-risk patients and possibly trigger more effective interventions in selected patients
Le malattie infiammatorie croniche intestinali. In: Manuale di Gastroenterologia. UNIGASTRO. Coordinamento Nazionale Docenti Universitari di Gastroenterologia.
No full textSurgery for inflammatory bowel disease in the era of laparoscopy
No full textDuring the course of inflammatory bowel disease (IBD), surgery may be needed. Approximately 20% of patients with ulcerative colitis (UC) will require surgery, whereas up to 80% of Crohn's disease (CD) patients will undergo an operation during their lifetime. For UC patients requiring surgery, total proctocolectomy and ileoanal pouch anastomosis (IPAA) is the operation of choice as it provides a permanent cure and good quality of life. Nevertheless a permanent stoma is a good option in selected patients, especially the elderly. Minimally invasive surgery has replaced the conventional open approach in many specialized centres worldwide. Laparoscopic colectomy and restorative IPAA is rapidly becoming the standard of care in the treatment of UC requiring surgery, whilst laparoscopic ileo-cecal resection is already the new gold standard in the treatment of complicated CD of terminal ileum. Short term advantages of laparoscopic surgery includes faster recovery time and reduced requirement for analgesics. It is, however, in the long term that minimally invasive surgery has demonstrated its superiority over the open approach. A better cosmesis, a reduced number of incisional hernias and fewer adhesions are the long term advantages of laparoscopy in IBD surgery. A reduction in abdominal adhesions is of great benefit when a second operation is needed in CD and this influences positively the pregnancy rate in young women undergoing restorative IPAA. In developing the therapeutic plan for IBD patients it should be recognized that the surgical approach to the abdomen has changed and that surgical treatment of complicated IBD can be safely performed with a true minimally invasive approach with great patient satisfaction
Activated intestinal lymphocytes in inactive Crohn's disease (CD) as a subclinical marker of early clinical relapse
No full textESCHERICHIA COLI PORIN INDUCES PROINFLAMMATORY ALTERATIOS IN RENAL TUBULAR EPITHELIAL CELLS
No full textEx-vivo autoradiography and FACS-scan analysis demonstration of a specific binding between IL2-receptor positive cells in Crohn's disease gut and I-123-interleukin-2 injected in vivo.
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