17 research outputs found
Patterns of tubercular lymphadenitis encountered in routine cytology reporting: An experience in a tertiary care center of Northeastern part of India
No full textBackground: Tuberculosis (TB) is the thirteenth leading cause of death and the second leading infectious killer after COVID-19 worldwide in 2020. Fine-needle aspiration (FNA) cytology is a simple and economic procedure for the diagnosis of TB at the initial stage. In this study, we tried to study the various cytomorphological patterns of tubercular lymphadenitis encountered in routine practice.
Materials and Methods: This is a retrospective study that was carried out in a tertiary care setting in north eastern India between 2019 and 2022. We retrieved 305 cases of tubercular lymphadenitis and classified them into 4 morphological patterns. These were: pattern A-Epithelioid granuloma without necrosis; pattern B-Epithelioid granuloma with necrosis; pattern C-Necrosis without epithelioid granuloma and with numerous neutrophilic infiltrate; and pattern D-Cases with numerous macrophages.
Results: In our study, pattern C was the most common (44%) followed by pattern (23%); pattern B was seen in 80 cases (26%); and pattern D was seen in only 22 cases (7%). Among patients with HIV infection, the most common pattern was pattern D (80%).
Conclusion: This study shows that TB lymphadenitis is a disease with various morphological patterns. And understanding it can aid in the accurate diagnosis of tubercular lymphadenitis
Intersecting paths: A rare case report of malignant melanoma in a patient with body dysmorphic disorder
No full textBackground: Body dysmorphic disorder (BDD) characterized by excessive and persistent preoccupation with perceived defects or flaws in appearance and has a prevalence of 1.7-2.9%. It is a disorder with a relatively unclear etiology.
Case presentation: A 36-year-old unmarried female presented to the surgery department with a self-inflicted lesion on her right ankle. The patient underwent fine needle aspiration cytology, and later, a wide local excision of the lesion was done. The final histological diagnosis of malignant melanoma was established. On careful psychiatric evaluation, the patient had an excessive and persistent preoccupation with her appearance, which caused severe psychological and social morbidity and drove her to her actions. Thus, the final diagnosis of body dysmorphic disorder (DSM V) was established. The patient was put on Fluoxetine and cognitive behavioral therapy.
Conclusion: Given the significantly reduced functionality and quality of life, BDD should be recognized and accurately diagnosed
Eyelid Tumors: A Potpourri of Three Cases
No full textThe eyelid is one of the most common sites for non-melanocytic skin tumors like basal cell carcinoma, squamous cell carcinoma and various skin adnexal tumors. of these, squamous cell carcinoma and basal cell carcinoma comprise 90% of all the eyelid tumors worldwide.The authors present three cases, which all presented with a mass in the eyelid.Case 1-A 70-year-old female presented with mass in the upper eyelid since 9 months.Case 2-A 65-year-old female presented with an ulcero-infiltrative nodule in the upper eyelid since 5 years with gradual increase in size since 5 months.Case 3-A 50-year-old male presented with an erythematous nodule in the upper eyelid since 1 year.Results: Based on the histopathological findings, diagnosis of sebaceous cell carcinoma, basal cell carcinoma, and squamous cell carcinoma was given.Discussion: Among the eyelid tumors in India, basal cell carcinoma is the most common with almost equal incidence closely followed by squamous cell carcinoma. Of the two, basal cell carcinoma has a better prognosis and sebaceous gland carcinoma has a higher mortality and therefore should be treated much more aggressively
Fluctus, Duikcentrum NL: De plek om de onderwaterwereld te ontdekken
No full textEen duikcentrum in Scharendijke te Zeeland. Een centrum waar versce onderschillende doelgroepen onder 1 dak worden samengebracht. De doelgroepen krijgen educatie in het onderwaterleven van Nederland. Tevens kunnen ze gebruik maken van de verschillende faciliteiten van het gebouw om een leuke dag uit te hebben. Het duiken staat centraal en geet je uiteindelijk de mogelijkheid om in de Grevelingen de echt onderwaterwereld van Nederland te ervaren.Explorelab 9ArchitectureArchitectur
Evaluation of the significance of tumor stromal patterns and peri-tumoral inflammation in head and neck squamous cell carcinoma with special reference to the Yamamoto–Kohama classification
No full textIntroduction:
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide with 878,348 new cases. Cancer-associated fibroblasts (CAFs) are the predominant cell type in tumor stroma and are important promoters of tumor progression.
Objective:
The aim of the study was to evaluate the pattern of desmoplastic stromal reaction and peri-tumoral inflammatory infiltrate with the histological grade and clinical data.
Materials and Methods:
A total of 60 cases of HNSCC were included in the study. The hematoxylin and eosin (H and E)-stained sections from all cases were examined by two experienced pathologists for the grade, nature of stomal reaction (SR), peri-tumoral inflammatory infiltration, Yamamoto–Kohama classification grade, worst pattern of invasion (WPOI), depth of invasion (DOI), and other histopathological parameters. Correlation analysis was conducted using the Chi-square test. P-value less than 0.05 was considered statistically significant.
Results:
Immature SR was not observed in any of the well-differentiated squamous cell carcinoma (SCC) cases. However, one (3.7%) case of moderately differentiated SCC and two (28.6%) cases of poorly differentiated SCC showed signs of immature SR. In the case of the higher grades of the YK classification, specifically grades 4C and 4D, a more profound depth of tumor cell invasion, equal to or exceeding 10 mm, was evident in six (66.67%) and two (28.57%) cases, respectively. Additionally, among the seven (11.7%) cases classified as poorly differentiated carcinoma, three (42.85%) displayed a WPOI score of 5.
Conclusion:
SR and the tumor invasive pattern in HNSCC are related to prognosis and may indicate tumor aggressiveness
A Systematic Review of the Effects of Bhramari Pranayama on the Central and Autonomic Nervous System
No full textThis systematic review is an investigation into the effects of Bhramari pranayama (Bhramari), a yogic breathing practice, and its effects on the central and autonomic nervous systems. To be eligible for inclusion a study must have reported using a variant of Bhramari, which at minimum must have included nasal breathing and humming, any studies combining these two aspects but not defining them as Bhramari were also eligible. Further, the studies must have included one or more markers or tests of autonomic nervous system activity, central nervous system activity, and/or cognitive function. Studies with treatment groups combining Bhramari with other interventions were excluded. ScienceDirect, Scopus, Web of Science, ClinicalKey, EBSCO Health Databases and MEDLINE were last searched on the 8th of December using the term “Bhramari” and eighteen studies were deemed fit for inclusion. The first author extracted results from the included studies into extensive excel tables, which were then summarized to create summary tables, and a risk of bias assessment using the Cochrane risk-of-bias tool for randomized trials (RoB 2). The studies reviewed revealed a modest but consistent, shift to parasympathetic dominance in ANS metrics, increase in paroxysmal gamma waves and alteration of wave power and expression in EEG reading, and increased concentration and accuracy in cognitive assessments. This was present over the domains of autonomic functioning, central nervous system function and cognitive testing. However, the risk of bias assessment resulted in a high risk of bias result for the majority of studies assessed. This is reflective of the large heterogeneity of studies reviewed with heterogeneity being present as far as Bhramari implementation. Therefore, further research should focus on verifying existing findings with more rigorous publications along with methods designed to better deduce mechanism of effect
Vergassing van steenkool in een gefluidiseerd bed
No full textDocument(en) uit de collectie Chemische ProcestechnologieDelftChemTechApplied Science
INDIAN MINIATURES (PAHARI PAINTINGS A STUDY OF INDIAN LANDSCAPES, SOCIAL LIFE AND LOVING SONGS OF GEET GOVINDA)
No full textThe article highlights the history of the Indian miniature as a carrier of unique
cultural information. The author considers the artistic miniature not only as a special genre
of Indian culture, but also as a means of transmitting social traditions, culture, values,
including religious ones. Pahari and Kangra miniatures are considered under the direct
influence of the topos, in the context of their historical and chronological development. The
author gives a commentary on each miniature, its color painting, highlights the main themes
and images, connects local motifs with the history of the country, religion
From Pt. Lookout, 1200 ft. above river, up canon to Lower Falls (308 ft.) Yellowstone Park, U.S.A.
No full textYou are looking about S. W. from a projecting angle in the rim of the Canon; it is half a mile from here to the precipice where you see the Yellowstone river flinging itself over and breaking into clouds of mist and spray. The Canon Hotel and the highway followed by coaches are off at your right on this (north) side of the river. Lake Yellowstone, whose waters are pouring over that cliff at the rate of some 90,000 cubic feet per minute, is 17 miles away beyond that dip in the horizon at the left. the lake is not actually the source of the river, but only like a big pendant on the river's ribbon-parts of this rushing flood come from mountains at the south of the Park limits; the stream is carrying off the surface drainage of 1900 square miles as a contribution to the Missouri, 350 miles away, behind you in North Dakota. The walls of the canon along here average nearly 1000 geet high, and these cliffs worn and eaten out by the raging waters show all sorts of gorgeous coloring-reds, yellows, every tone of burnt orange and sulphur and brown. The rock formation is nearly all rhyolite, a volcanic stuff piled up here ages ago by eruption from the crater of an old-time volcano; the wearing out of this magnificent gorge has been accomplished partly by the mechanical action of the running waters and partly by their chemical action, during long ages when the stream must have been hot and strongly charged with solution of corrosive mineral stuff from the geyser basins. From Notes of Travel No. 13, copyright 1904 by Underwood & Underwood
