2,281 research outputs found
Patients With Prior Myocardial Infarction,Stroke,or Symptomatic Peripheral Arterial Disease in the CHARISMA Trial
No full textChina and the BRI: Challenges and Opportunities for Southeast Asia
No full textSince Xi Jinping’s unveiling, in 2013, the Belt and Road Initiative (BRI) has drawn remarkable global attention, raising polarized judgements about China’s ambitions. A number of countries and institutions enthusiastically considered the BRI as a valuable infrastructural and economic contribution that would enhance connectivity among Eurasian countries; on the other hand, critics viewed the BRI as part of Beijing’s effort to gain global influence, especially within its neighborhood. Chinese policymakers have considered Southeast Asia as a critical region for the success of the BRI, mainly because of the geographical proximity as well as the strong economic ties with both individual states and the ASEAN. In Southeast Asian states’ view, however, the BRI still presents a mixed picture of opportunities and challenges. Despite the clear appeal the BRI has to both democratic and authoritarian leaders in the region, especially at a time of economic uncertainty—fueled by unhelpful actions by the United States (withdrawal from the TPP and the trade war against Beijing)—concerns remain. Potential overdependence on China, the BRI’s financial sustainability and negative popular perceptions about Beijing within certain Southeast Asian countries, all contribute to nurture caution in the region. The paper aims at showing how the implementation of the BRI will likely enhance China’s influence in Southeast Asia. Against this backdrop, whereas the establishment of a renovated Sinocentric system is far from certain, this study sheds light on the challenges and opportunities the BRI is determining upon Southeast Asian countries and their relationship with Beijing
Does SGLT1 inhibition add to the benefits of SGLT2 inhibition in the prevention and treatment of heart failure?
No full textSupplemental material for Thrombolytic therapy in older acute ischemic stroke patients with gastrointestinal malignancy or recent bleeding
No full textSupplemental Material for Thrombolytic therapy in older acute ischemic stroke patients with gastrointestinal malignancy or recent bleeding by Taku Inohara, Li Liang, Andrzej S Kosinski, Eric E Smith, Lee H Schwamm, Adrian F Hernandez, Deepak L Bhatt, Gregg C Fonarow, Eric D Peterson and Ying Xian in European Stroke Journal</p
The “Triangle” Sign: A Novel Ultrasound Marker for Diagnosing Total Choroidal Detachment and Total Suprachoroidal Hemorrhage
No full textVaidehi D Bhatt,1 Deepak C Bhatt,1 Kalpana D Bhatt,1 Supriya Dabir,2 Tos TJM Berendschot,3 Roel J Erckens,3 Carroll AB Webers3 1UBM Institute, Mumbai, India; 2Department of Retina, Rajan Eye Care Pvt Ltd, Chennai, India; 3University Eye Clinic Maastricht, Maastricht, the NetherlandsCorrespondence: Vaidehi D Bhatt, UBM Institute, A/1 Ganesh Baug, Dadar, Mumbai, 400019, India, Tel +91-9821525810, Email [email protected]: This study aims to explore the diagnostic utility of ultrasound B-scan while introducing the “Triangle” sign as a novel indicator. It also validates the sign’s efficacy in distinguishing between choroidal detachment (CD) and suprachoroidal hemorrhage (SCH) from retinal detachment (RD) and vitreous hemorrhage (VH).Patients and Methods: Retrospective analysis of consecutive cases of total CD and SCH undergoing B-scan at a single tertiary imaging center. The study examined the presence of the “Triangle” sign (a hypoechoic/anechoic triangular shape of vitreous noted anterior to the optic disc) in total CD & SCH, categorized cases by subtype and etiology, and its role in differentiating from RD and VH.Results: Thirty-six eyes with a total CD and SCH were analyzed. Amongst the cases of total SCH 31 (86.1%), (58.1%) were linked to intraocular surgery, and (41.9%) were linked to post-traumatic events. The “Triangle” sign was consistently present in all 36 eyes, with additional findings indicating concurrent VH (52.8%) or RD (5.6%). Among the 31 eyes with total SCH, 58.3% initially had detectable choroidal membrane seen on B scan, while 41.7% did not. Despite this, the “Triangle” sign was consistently visible in all 36 eyes, and monitoring with B-scans revealed choroidal membrane as the hemorrhage resolved.Conclusion: The “Triangle” sign is a distinctive and reliable ultrasound feature for total CD and SCH diagnosis, offering clarity in challenging cases where traditional methods face limitations.Keywords: choroidal detachment, suprachoroidal hemorrhage, ultrasound B-sca
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Relational Care - with Mary Larkin and Manik Deepak-Gopinath [Podcast]
No full textWhat is 'relational care' and how can it improve the day-to-day experience of carers and those they care for? What are its implications for relationships between staff and service users in care settings? And how does the concept of relational care enable us to re-imagine the role of place and space in the experience of care? These are some of the questions we explore in this episode with Mary Larkin and Manik Deepak-Gopinath who recently completed a research project on the value and practice of relational care with older people.
Mary is Professor of Care, Carers and Caring at The Open University in the UK, where her research has focused on carers and caring and adult social care. She is the co-author, most recently of Family Carers and Caring, published in 2023 by Emerald. Manik is a Lecturer in Ageing, also at The Open University, and is a critical gerontologist with interests in the intersection of ageing, place and wellbeing, and in the intimate and family ties of older adults
My Name Is Deepak
No full textThis chapter looks at the author's responses to being given a nickname by his co-workers: Tupac. They do it in a friendly manner, but the author doesn’t understand the connection with the American rapper. It makes him think about who he is, his identity, and how people see him in his adopted country.</p
SYMPLICITY HTN-3: failure at 6 months, success at 3 years?
No full textIn The Lancet, Deepak L Bhatt and colleagues report long-term outcomes of renal artery denervation in patients denervated by single-electrode radiofrequencywithin the SYMPLICITY HTN-3 study. [...
Sideffective - system to mine patient reviews: sentiment analysis
No full textSideffective is the system to crawl, rank and analyze patient testimonials about side ffeects from common medications. Since the wealth of any mining model is the Data corpus, the data collection phase involved extensive crawling of massive medical websites comprised of user forums from the internet. Subsequently, the raw files were subjected to certain site-specific parsing routines, yielding outputs conforming to a well-defined data model. Currently, the system holds close to 400,000 user testimonials pertaining to more than 2500 drugs/medicines. Sideffective aims at gathering and aggregating this wealth of information, build useful associations and present interesting observations and numeric validations, all in a user-friendly interface. The important issues that we have tried to tackle are: Extracting side effects without relying on pre-built lists, aggregating distribution of different side effect for a give drug, site-specific search, ranking and determining the negativity of reviews. The system has been jointly built by Deepak Yalamanchi and Sangeetha Rajagopalan under the guidance of Prof. Tomasz Imielinski. This thesis focuses mainly on Sentiment Analysis of patient reviews. While most existing sentiment analysis systems are predicated by POS (parts of speech) tagging or Bayesian sentiment analysis methods, the same cannot be applied to medical reviews as they generally carry a negative flavor in them. We thereby approached the problem by identifying the features in the sentence and calibrating the sentiment on a Negativity Meter based on their relation to sentiment words. A feature, as defined for the purpose of this thesis, can be a medicine, a side effect or a symptom. The sentiment of each feature is determined by the aggregate of all its polarities with respect to each sentiment word, where the polarity is determined by an inverse relation to the distance of the feature from the sentiment word. Each sentence is then evaluated by the cumulative polarity of all the features contained in it. Sentiment of a review is determined by individually determining the sentiment of each sentence and then getting a weighted sum score of all the sentences in the review. The accuracy of a sentiment analysis system is, in principle, how well it agrees with human judgments. Experimental results, involving human reviewers (extracted from site: www.askapatient.com) and correlating them back to the negativity rating of each review yield conclusive results, demonstrating the effectiveness of the technique. We have also implemented a customized Lucene search on the data using a multi-review summarization approach and a ranking scheme based on the feature-list. Ranking priority is given to the review that has the largest feature list size.M.S.Includes bibliographical referencesby Deepak Yalamanch
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