6,861 research outputs found
A Partial Ossicular Replacement Prosthesis With a Concentric Ball Joint in the Headplate
No full textObjective
In passive middle ear prosthetics, rigid implants have proven successful in reconstructing the ossicular chain. However, these cannot fully replicate the physiology of the ossicular chain. Pressure fluctuations cause high stresses in rigid passive prostheses, which can result in dislocation, protrusion, and pre-tension in the annular ligament resulting in unsatisfactory hearing results.
Methods
In collaboration with MED-EL, we developed a new passive middle ear prosthesis that features a balanced, centered ball joint between the headplate and shaft of the prosthesis. We compared the sound transmission properties of this new prosthesis with those of a standard rigid prosthesis. Using Laser-Doppler-Vibrometry, we measured the sound-induced velocity of the stapes footplate relative to a given acoustic stimulus.
Results
The new prosthesis showed equivalent sound transmission characteristics compared to the rigid prosthesis, whereas retaining the ability to compensate for pressure fluctuations due to its ball joint. This ensures good transmission properties even during displacements of the tympanic membrane.
Conclusion
This development is a further step toward a physiological reconstruction of the ossicular chain.MED-EL Medical Electronics https://doi.org/10.13039/50110001885
Die Entwicklung einer passiven Mittelohrprothese mit konzentrischem Mikrokugelgelenk in der Kopfplatte – erste Ergebnisse im Felsenbeinexperiment
No full textThe development of a passive middle ear prosthesis with concentric microsphere joint in the head plate – first results from temporal bone experiments
No full textAccess to the Apical Cochlear Modiolus for Possible Stem Cell-based and Gene Therapy of the Auditory Nerve
No full textInterview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American City
Full text linkInterview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American Cit
Nitinol in Passive Ossicular Reconstruction—First Results From Temporal Bone Experiments
No full textSafety and efficacy of the mAXIS stapes prosthesis
No full textAbstract Purpose Otosclerosis leads to a fixed stapes footplate and thus to hearing loss. The predominant treatment method is surgery, with various types of stapes prostheses available. The aim of this study was to investigate the safety and efficacy of the new mAXIS Stapes Prosthesis. Methods 34 cases of otosclerosis were implanted with the new mAXIS Stapes Prosthesis. Comprehensive clinical assessments, including pre- and postoperative pure tone audiometry was performed at short-term (ST) follow-up at 25 (± 15) days and mid-term (MT) follow-up at 181 (± 107) days. The pure tone average of 0.5, 1, 2 and 3 kHz (PTA4) was calculated. Results In all cases, the application of the prosthesis was successful and straightforward. The postoperative PTA4 air-bone gap was 10.7 ± 5.2 dB at ST follow-up ( n = 34) and 8.3 ± 4.1 dB at MT follow-up ( n = 18). In 61% of cases, the ABG-closure was within 10 dB and in 100% of cases within 20 dB at MT follow-up. Conclusion Findings of this study support that the mAXIS Stapes Prosthesis is safe for implantation and shows promising audiological outcome. Future investigations will contribute its long-term efficacy and safety profile
Partial Ossicular Reconstruction With a Novel Ball Joint Prosthesis: The mCLIP ARC Partial Prosthesis
No full textObjective
Middle ear surgery involves reconstruction of the ossicular chain, predominately using rigid implants. New middle ear prostheses strive to mimic the physiologic micromovements of the ossicular chain and prevent dislocation, protrusion, and preloading of the annular ligament due to pressure fluctuations.
Methods
Thirty‐five patients were included in a monocentric, prospective observational study. Patients received tympanoplasty with ossicular reconstruction using the mCLIP ARC partial prosthesis. This titanium prosthesis is equipped with a clip mechanism for coupling at the stapes and a ball joint connecting headplate and shaft. At short‐term (ST) and mid‐term (MT) follow‐up, pure‐tone audiometry was performed and the pure tone average of 0.5, 1, 2, and 3 kHz (PTA4) was calculated. The audiological outcome was compared with retrospective data of the Dresden titanium clip prosthesis.
Results
The new prosthesis shows favorable clinical results. Pure‐tone audiometry showed satisfactory results in ST and MT follow‐up, with the PTA4 air‐bone gap (ABG) decreasing from 24.5 (±11) dB to 17.4 (±7.9) dB at the ST follow‐up at 27 days to 15.6 (±10.3) dB at MT follow‐up at 196 days (
n
= 32). A PTA4‐ABG value of less than 20 dB was achieved by 63% of patients at ST follow‐up and by 77% at MT follow‐up. There was no significant difference in PTA4 ABG compared to the Dresden titanium clip prosthesis during ST follow‐up (
p
= 0.18).
Conclusion
The mCLIP ARC partial prosthesis, a new middle ear prosthesis with a balanced ball joint, shows promising audiological results and is a safe and effective choice for patients with chronic ear disease.
Level of Evidence
3
Laryngoscope
, 2024MED-EL Medical Electronics https://doi.org/10.13039/50110001885
Book review: Freya Johnston and Matthew Bevis (eds), Thomas Love Peacock Crotchet Castle / Nicholas A. Joukovsky (ed.), Thomas Love Peacock Nightmare Abbey
No full textReview of: Freya Johnston and Matthew Bevis (eds), Thomas Love Peacock Crotchet Castle. Pp. cxxii + 328 (The Cambridge Edition of the Novels of Thomas Love Peacock). Cambridge: Cambridge University Press, 2016. £79.99 (ISBN 978 1 107 93972 5).
&
Nicholas A. Joukovsky (ed.), Thomas Love Peacock Nightmare Abbey. Pp. cxlii + 297 (The Cambridge Edition of the Novels of Thomas Love Peacock). Cambridge: Cambridge University Press, 2016. £84.99 (ISBN 978 1 107 03186 9).
The idiosyncratic joy of Thomas Love Peacock’s works is highlighted within wonderfully readable scholarly introductions from, Nicholas A. Joukovsky who edits Nightmare Abbey, and, Freya Johnston and Matthew Bevis in their edition of Crotchet Castle. These new editions are the first thoroughly edited and annotated imprints of Peacock since the Halliford Edition of the Works, edited between 1924 and 1934 by H.F.B. Brett-Smith and C.E. Jones for Constable
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