1,199 research outputs found
sj-docx-1-ijs-10.1177_10668969241236704 - Supplemental material for The Histopathologic Features of Early COVID Pneumonia in a Pediatric Patient: New Insight into the Role of Macrophages
No full textSupplemental material, sj-docx-1-ijs-10.1177_10668969241236704 for The Histopathologic Features of Early COVID Pneumonia in a Pediatric Patient: New Insight into the Role of Macrophages by Philip L. Bulterys, Guangwu Xu, Benjamin A. Pinsky, Megan L. Troxell, Joshua R. Menke, Gerald J. Berry, Sebastian Fernandez-Pol and Florette K. Hazard in International Journal of Surgical Pathology</p
Compositional gradient effects on stress corrosion cracking behavior of weld metal
No full textIncludes bibliographical references
Infant Bayley Scores and Full Day Arm Movement Data
No full textPlease see "Relationships between full-day arm movement characteristics and developmental status in infants with typical development as they learn to reach: An observational study" in Gates Open Research. Authors are Joanne Shida-Tokeshi, Christianne J. Lane, Ivan A. Trujillo-Priego, Weiyang Deng, Douglas L. Vanderbilt, Gerald E. Loeb, and Beth A. Smith. Beth A. Smith is the corresponding author
Melanotaenia nigrans Richardson
No full textMelanotaenia nigrans Richardson Blackbanded Rainbowfish Extremely rare within the Kimberley region, Melanotaenia nigrans is only known from one small tributary in Dominic Creek near the mouth of the King Edward River (Fig. 21), and although WAM records suggest it is present in Yampi Sound, recent examination of these specimens by the senior author revealed them to be M. australis. The species is also found in coastal drainages of the Northern Territory, including Groote Eylandt and the northern tip of Cape York (Allen et al. 2002).Published as part of Morgan, David L., Allen, Gerald R., Pusey, Bradley J. & Burrows, Damien W., 2011, 2816, pp. 1-64 in Zootaxa 2816 on page 1
Le origini di Homo e le origini dell'esperienza estetica
No full textThis article explores the possibility of conceiving of the origins of aesthetic experience as a major evolutionary discontinuity directly correlated with anthropogenesis.
After a brief examination of some traces of primitive art, and taking into account some relevant ideas by Aristotle, Alberti, Hegel, Merleau-Ponty, Plessner, and Gerald Edelman, the author discusses the conditions under which “sensation” (aisthetis) could become a complex “experience”, byevoking the image of, or referring to, absent objects
Analyzing the effects of U.S. agricultural policy on Mexican agricultural markets using the MEXAGMKTS model
Get PDFThis paper uses results from simulations of the FAIRMODEL, USAGMKTS, and MEXAGMKTS models to analyze the effects of changes in U.S. agricultural policy on Mexican agricultural markets. The author concludes that under a scenario of trade liberalization for Mexico, Mexican agricultural production, prices, and trade are quite sensitive to agricultural policy changes in the U.S. The genesis of the research project was the perception that agricultural policies in Mexico (and many other countries) are often second best responses to the negative side effects of broad economic policies aimed primarily at macroeconomic and international trade objectives. The paper also discusses the role of agriculture in Mexican economic policy, and MEXAGMKTS, FAIR and USAGMKTS models. The paper includes an analysis of the sensitivity of Mexican agricultural markets to U.S. agricultural policy and a brief summary of the implications of the results.Environmental Economics&Policies,Economic Theory&Research,Agricultural Research,Access to Markets,Markets and Market Access
Generation of the sodium/myo-inositol cotransporter 1 (Slc5a3) gene murine knockout model, characterization of its lethal phenotype, and revision of the ‘inositol depletion hypothesis’
Get PDFMyo-inositol (Ins) is a ubiquitous hexahydroxycyclohexane in living organisms, and the most abundant in mammalian cells of all nine possible stereoisomers along with scyllo-, neo-, epi-, muco-, allo-, cis-, and the enantiomers, D-chiro and L-chiro. Ins is an important osmolyte and a key component of phosphatidylinositol (PtdIns), unique in the family of phospholipids in that its Ins headgroup can be further phosphorylated to generate various phosphoinositides. Among them, phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) is involved in important signal transduction events. Ins’s cellular uptake is carried out by a system of specific membrane transporters, of which the SLC5A3 (SMIT1), a Na+/myo-inositol cotransporter, is the one with the highest affinity for the polyol.The principle aim of my thesis work is to test the widely accepted “myo-inositol depletion hypothesis” envisioned to explain the mechanism of action of lithium, complications of diabetes and hereditary galactosemia. This assumption, which states that a reduction of intracellular myo-inositol results in a decreased PtdIns synthesis, and therefore a disruption of cellular signaling, had never been tested by direct measurements of PtdIns. To investigate the effect of Ins deficiency at the cellular level, a murine knockout model of the Slc5a3 gene encoding the Na+/Ins cotransporter was generated and studied. The resulting Slc5a3-null mice die shortly after birth, although the phenotype can be rescued by supplementation of 1% Ins in the drinking water of the pregnant dam. The rescued Slc5a3 knockout mice survive only if the Ins enriched water treatment continues until weaning, 14 days after birth.My work shows that a 69.7% reduction in myo-inositol is responsible for a 47% reduction of PtdIns in the murine Slc5a3–null fetus at embryonic stage 10.5, but the hypothesis proves to be invalid at later stages of development, at embryonic stages 14.5 and at 18.5, and through adulthood. The work outlined in this dissertation also shows that the ‘Ins depletion hypothesis’, as it has been proposed, proves to be invalid since Ins levels in mammalian tissues have never been shown to be reduces to the degree observed in Slc5a3 knockout mouse model used in my study.Ph.D., Biomedical Science -- Drexel University, 201
Haemorrhagic kidney syndrome of Atlantic salmon, Salmo salar L.
No full textThis report describes a new syndrome affecting farmed Atlantic salmon on the Canadian east coast that has resulted in increased morbidity and mortality in affected stocks. The major pathological findings are apparent only microscopically and include renal interstitial haemorrhage and acute tubular necrosis and tubular casting. As a result, the disease has become known as haemorrhagic kidney syndrome (HKS). Affected fish are lethargic and anorectic, and lark external lesions. Clinically, HKS fish are anaemic, hypoproteinaemic and hyperosmolalic, with increased serum concentrations of sodium and chloride. At necropsy, internal changes ranged from apparently normal to include one or several of the following: swelling and/or patchy reddening of the kidney, pale gills, exophthalmos, serosanguinous ascites, darkening of the posterior intestine and splenomegaly. Ultrastructurally, viral inclusions were found in the cytoplasm of erythrocytes of HKS fish, and there were unusual electron-dense inclusions within the tips of renal tubular microvilli of HKS fish. The significance and relevance of the ultrastructural findings to HKS are unknown. Virus isolation was attempted using CHSE, RTG-2, FH-10, BE and EPC cell lines; no virus was isolated. Bacteriological analysis failed to reveal significant pathogens. Analysis of tissues for heavy metals and pesticides was negative. Assays for clostridial toxins, lipopolysaccharide and verotoxins were negative. The aetiology of HKS remains unresolved.PT: J; CR: AHNE W, 1989, VIRUSES LOWER VERTEB, V3 ARMSTRONG R, 1993, CAN VET J, V34, P312 AUSTIN B, 1993, BACTERIAL FISH PATHO BOVO G, 1995, DIS AQUAT ORGAN, V21, P115 CONFER AW, 1995, THOMSONS SPECIAL VET, P209 DANNEVIG BH, 1995, J GEN VIROL, V76, P1353 EATON WD, 1993, J GEN VIROL, V74, P2299 EVENSEN O, 1991, RES VET SCI, V51, P215 FERGUSON HW, 1982, VET PATHOL, V19, P687 FOOTT JS, 1992, J AQUAT ANIM HEALTH, V4, P306 HETRICK FM, 1993, ANN REV FISH DIS, V3, P187 KIMURA T, 1986, DIS AQUAT ORGAN, V1, P209 KIMURA T, 1989, VIRUSES LOWER VERTEB, V3 KOSKI P, 1992, BULL EUR ASSN FISH P, V12, P177 LAMAS J, 1995, J FISH DIS, V18, P425 MEIER W, 1994, ANN REV FISH DIS, V4, P359 NOUGAYREDE P, 1992, B EUROPEAN ASS FISH, V12, P5 PINTO RA, 1992, J AQUATIC ANIMAL HLT, V4, P292 ROBERTS RJ, 1994, RECENT ADV AQUACULTU, V5 SANO T, 1995, AQUACULTURE, V132, P43 SMITH LS, 1975, MISCELLANEOUS SPECIA, V27 SPEILBERG L, 1995, VET PATHOL, V32, P466 THOESEN JC, 1994, BLUE BOOK SUGGESTED TISHER CC, 1989, RENAL PATHOLOGY CLIN, V1 WADDELL TE, 1996, INFECT IMMUN, V64, P1714 WOLF K, 1988, FISH VIRUSES FISH VI WOOD CM, 1995, PHYSL ECOLOGY PACIFI; NR: 27; TC: 29; J9: J FISH DISEASES; PG: 11; GA: 170XZSource type: Electronic(1
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