1,721,042 research outputs found
The sutureless and rapid-deployment aortic valve replacement international registry: Lessons learned from more than 4,500 patients
Full text linkThe treatment options for patients with aortic valve disease have considerably expanded over the last decade. The remarkable advances in catheter-based technology, the popularizing of minimally invasive (MI) surgery, and the introduction of new valve technologies, such as sutureless and rapid-deployment (SURD) valves have led to a paradigm shift in the management of aortic valve pathologies. Yet, given their recent introduction, the current evidence on sutureless and rapid-deployment aortic valve replacement (SURD-AVR) has been limited thus far. The Sutureless and Rapid-Deployment Aortic Valve Replacement International Registry (SURD-IR) was established in 2015 by a consortium of 18 research centers to assess safety, efficacy, short-and long-term outcomes of SURD-AVR interventions. The present keynote lecture aims to assess and comment on the real-world evidence for SURD-AVR surgery generated from the SURD-IR
New technology: The sutureless valve prostheses
Full text linkThe sutureless concept of aortic valve implantation was developed in the early 1960s; however, this approach fell out of favour due to frequent valve-related thromboembolic complications and severe paravalvular leakage. More recently, with the advent of bovine pericardial valve prostheses, new sutureless and rapid deployment aortic valve prostheses have been reintroduced based on modern experience with transcatheter aortic valve implantation. There are two types of sutureless and rapid deployment aortic prostheses currently available on the market: the PercevalTM (LivaNova, Saluggia, Italy) and the Intuity EliteTM (Edwards Lifesciences, Irvine, Calif., USA) valves. By avoiding the placement and tying of sutures, sutureless aortic valve replacement (SU-AVR) has shown to minimize operative times and facilitate minimally invasive approaches. Moreover, current evidence suggests that sutureless and rapid deployment valves provide excellent haemodynamic results. Nevertheless, there is still a paucity of robust evidence on long-term SU-AVR outcomes; thus, to adequately assess the encouraging haemodynamic profile and the durability of these prostheses, further clinical trials are warranted
'Double layer' frozen elephant trunk with balloon endoclamping: A technique to simplify the 2-stage open repair of thoraco-abdominal aortic aneurysms
Full text linkStaged replacement of the aortic arch and thoraco-abdominal aorta (TAA) with a frozen elephant trunk followed by TAA repair is a valuable treatment for patients with chronic TAA dissection. However, in patients with an unclampable descending thoracic aorta, the retrieval of the trunk can be problematic and the proximal stent graft-to-graft anastomosis technically challenging. Here we present our 'double layer' frozen elephant trunk technique to treat patients with TAA dissection
Vocali tematiche, suffissi zero e "cani senza coda" nella morfologia dell'italiano contemporaneo
No full textSurgical Treatment of Infective Endocarditis: Is There a Role for Rapid Deployment Aortic Valve Replacement
No full textSex enhancers: challenges, threats and the need for targeted measures
Full text linkHumans have always aimed to use substances for improving their cognitive, physical and sexual performances: ancient civilizations resorted to hallucinogens in the attempt to get into contact with their gods; the widespread use of caffeine in its various forms (caffeinated and energy drinks, tablets, etc.) and the more recent development of glutamate activators (1,2
Synthetic cathinones and cardiotoxicity risks
No full text: Recently, there has been a worldwide rise in the popularity and abuse of synthetic cathinones. The spectrum of side effects caused by the intake of these drugs of abuse is very wide since they act on different systems with various mechanisms of action, they appear to be involved in different cardiac events, including myocardial infarction and sudden cardiac death due to fatal arrhythmias. Overall, khat users have a higher risk of death, recurrent myocardial ischemia, cardiogenic shock, ventricular arrhythmia, and stroke compared with non-khat user
Minimally invasive aortic valve replacement with a catheter-based cerebral protection system: Transferring percutaneous technologies into a surgical intervention
Full text linkPatients with severe aortic valve stenosis are currently treated with 2 different interventional techniques: surgical aortic valve replacement or transcatheter aortic valve implantation (TAVI). Both have strengths and limitations. On the one hand, TAVI represents a valuable option in high- and intermediate-risk patients and is commonly preferred over surgical aortic valve replacement in subjects with porcelain or severely calcified aorta, on the other, the lack of data on valve durability raises concerns on its use in young, low-risk patients. We present herein the case of a low-risk 71-year-old patient with a severely calcified ascending aorta. We successfully combined our minimally invasive surgical approach with the use of a percutaneous cerebral protection system commonly employed during TAVI procedures. We believe that cardiac surgeons could adopt transcatheter technology to improve operative results
- …
