109,227 research outputs found
Die Fakultät als Großstadt und ihre intermediären Strukturen. Jörg Bergmann im Gespräch mit Ruth Ayaß und Sarah Hitzler
No full textBergmann JR, Ayaß R, Hitzler S. Die Fakultät als Großstadt und ihre intermediären Strukturen. Jörg Bergmann im Gespräch mit Ruth Ayaß und Sarah Hitzler. In: Kieserling A, Werron T, eds. Die Fakultät für Soziologie in Bielefeld. Eine Oral History. Bielefeld: transcript; 2019: 171-184
Kruppel-like factor 4 expression in normal and pathological human testes
No full textKrüppel-like factor 4 (KLF4) is a transcription factor involved in many cellular and developmental processes such as terminal differentiation of cells and carcinogenesis. Mice lacking KLF4 die post-natally due to skin barrier deficiencies and exhibit several additional cellular defects. The adult rodent testis expresses high levels of Klf4 mRNA. Using in situ hybridization, we previously localized most of the Klf4 mRNA to round spermatids in mice. Moreover, in rodent Sertoli cells, Klf4 is strongly inducible by FSH. Here, we show by northern blot analysis that the human testis also strongly expresses KLF4. Applying immunohistochemistry, we localized KLF4 protein to the nuclei of round spermatids during normal spermatogenesis stages II–IV. Analysing round spermatid maturation arrests, strong cytoplasmic staining could be seen in two samples. We failed to detect KLF4 in human Sertoli cells. Most human Leydig cells expressed KLF4 at high levels in the nucleus. However, some individual Leydig cells lacked KLF4, suggesting different functional states of the Leydig cells. The strong expression of KLF4 in the human testis and the importance of KLF4 in several mouse tissues suggest a significant role for KLF4 in the human testis. A first hint at a role for KLF4 during spermiogenesis could be the altered subcellular localization of the protein during arrested spermiogenesis.Behr, C. Deller, M. Godmann, T. Müller, M. Bergmann, R. Ivell and K. Stege
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
L'état présent de l'agriculture française examen des données statistiques
No full textBergmann Denis R. L'état présent de l'agriculture française examen des données statistiques. In: Annales de Géographie, t. 63, n°339, 1954. pp. 339-357
The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling
No full textAbstractThe Bergmann glia is a unipolar astrocyte in the cerebellar cortex, displaying a tight association with Purkinje cells. The cell bodies of Bergmann glia are located in a row around Purkinje cell somata; they extend radially arranged Bergmann fibers which enwrap the synapses on the Purkinje cell dendrites. It is well known that Bergmann glial somata migrate from the ventricular zone through the mantle zone, forming an epithelium-like lining in the Purkinje cell layer during development. However, the mechanism of the monolayer formation of Bergmann glia is poorly understood. Several reports have suggested that Notch signaling plays instructive roles in promoting the identities of several types of glial cells, including Bergmann glia. Moreover, Notch receptors are expressed in Bergmann glia during development. Here, we have deleted the Notch1, Notch2 and RBP-J genes in the Bergmann glia by GFAP-driven, Cre-mediated recombination, to study the role of Notch-RBP-J-signaling in the monolayer formation of Bergmann glia. Notch1/2- and RBP-J-conditional mutant mice showed disorganization of Bergmann fibers, irregularities of the Bergmann glial lining and aberrant localization of Bergmann glia in the molecular layer. Thus, Notch-RBP-J signaling plays crucial roles in the monolayer formation and morphogenesis of Bergmann glia
Grabbing subitizing with both hands: bimanual number processing
No full textPlaisier M, Bergmann Tiest WM, Kappers AML. Grabbing subitizing with both hands: bimanual number processing. Experimental Brain Research. 2010;202(2):507-512
NMDA-activated currents in Bergmann glial cells
No full textNMDA receptors play a crucial role in synaptic plasticity of the central nervous system and were thought to be exclusive to neurones. In this study we provide evidence that Bergmann glial cells from mouse cerebellar slices show intrinsic responses to NMDA. As in neurones, NMDA increased membrane conductance and the responses were blocked by the NMDA antagonist ketamine, but not by the non-NMDA glutamate receptor antagonist CNQX. In contrast to responses in neurones, the current voltage relation of the glial NMDA-induced current was linear, reversed at -40 mV, currents were not blocked by Mg2+ or enhanced by glycine and NMDA did not induce an increase in cytosolic Ca2+ as recorded with a fura-2 imaging system. These data imply the presence of distinct NMDA receptors on Bergmann glial cells; these glial receptors could be the substitute for complex neurone-glia interactions in the cerebellum
Neue religiöse Bewegungen. Religiöser Pluralismus in der westlichen Welt
No full textBarker E. Neue religiöse Bewegungen. Religiöser Pluralismus in der westlichen Welt. Ayaß R, Bergmann J, trans.; In: Bergmann J, Hahn A, Luckmann T, eds. Religion und Kultur. Kölner Zeitschrift für Soziologie und Sozialpsychologie. Sonderheft. Opladen: Westdeutscher Verlag; 1993: 231-248
Ouvrage Collectif, sous la direction de T. Bergmann et T.B. Ogura. - Cooperation in world agriculture experiences, problems and perspectives. Food and Agriculture
No full textKlatzmann Joseph. Ouvrage Collectif, sous la direction de T. Bergmann et T.B. Ogura. - Cooperation in world agriculture experiences, problems and perspectives. Food and Agriculture. In: Économie rurale. N°175, 1986. pp. 64-65
Developmental regulation of voltage-gated K+ channel and GABAA receptor expression in Bergmann glial cells
No full textBergmann glial cells are closely associated with neurons: during development they provide guiding structures for migrating granule cells and in the adult cerebellum they display intimate interactions with Purkinje cells. In this study, we have addressed the question of whether such changes in neuronal-glial interactions during development are accompanied by variations in the membrane properties of Bergmann glial cells. We used a mouse cerebellum slice preparation to study membrane currents of the Bergmann glial cells at various stages of development in situ using the patch-clamp technique. The distinct morphology of Bergmann glial cells was revealed by Lucifer yellow injections during recording. While Bergmann glial cells in mice of postnatal day 20 (P20) to P30 have thick processes with arborized, irregularly shaped leaf-like appendages, the processes of cells from younger mice (P5-P7) are thinner and smoother. This morphological maturation is accompanied by a variation in voltage-gated currents. In cells from P5 to P7, delayed outward- and inward-rectifying K+ currents were recorded, while older Bergmann glial cells were characterized by, large, voltage- and time-independent K+ currents. In addition, application of GABA induces two effects, a rapid activation of a Cl- conductance and a longer-lasting decrease in the (resting) K+ conductance. Both effects were mediated by benzodiazepine-insensitive GABAA receptors. Responses in cells of P5-P7 mice were large as compared to the small or even undetectable responses in P20-P30 cells. These GABAA receptors were characterized immunohistochemically in mice and rat brain sections with five subunit-specific antibodies. Bergmann glial cells exhibit a distinct but transient immunoreactivity for the GABAA receptor alpha 2-, alpha 3-, and delta-subunits. Staining is maximal between P7 and P10 and decreases gradually thereafter. In contrast, antibodies to the alpha 1- and beta 2,3-subunits fail to decorate Bergmann glial cells, although they yield a prominent staining of both the Purkinje cells and the granule cells. These changes in the Bergmann glial cell membrane properties and GABAA receptor expression suggest a transition between functional states during development of the Bergmann glial cells
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