2,138 research outputs found
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
GLOBALIZATION AND HEALTH: CHALLENGES FOR HEALTH LAW AND BIOETHICS
No full textPreface -- Acknowledgments -- Contributors -- Public health: developing global concerns -- Travel in a small world: SARS, globalization and public health laws / Belinda Bennett -- Globalization and health: a developing world perspective on ethical and policy issues / Udo Schüklenk and Braimoh Bello -- Globalization and clinical trials: compensating subjects in developing countries / George F. Tomossy and Jolyon Ford -- Ethics, disease and obligation / Deborah Zion -- The global bio-economy: consensus and innovation -- Regulating the bio-economy: a preliminary assessment of biotechnology and law / Derek Morgan -- The global context for risk governance: national regulatory policy in an international framework / Alan Irwin -- Global intellectual property protection of "innovative" pharmaceuticals: challenges for bioethics and health law -- Directing consumption: direct-to-consumer advertising and global public health / Patricia Peppin -- Globalization and biotechnology policy: the challenges created by gene patents and cloning technologies / Timothy Caulfield and Barbara von Tigerstrom -- Globalization and health care -- The rights of donor-conceived children to know the identity of their donor: the problem of the known unknowns and the unknown unknowns -- Globalization and English medical law: strains and contradictions / John Harrington -- Health practitioner regulation: emerging patterns and challenges for the age of globalization / Ian Freckelton -- Inde
Romance, op. 50
No full textMore Author/Title Info: Ludwig van Beethoven ; editions for double bass and piano by Timothy Cobb.
Uniform Title: Romances, violin, orchestra, op. 50, F major; arranged
Physical Description: 2 scores (10 pages) + 2 parts (4 pages) ; 28 c
Seminal contributions of Timothy J. Crow
No full text© The Author(s), 2025. Published by Cambridge
University Press. This is an Open Access article,
distributed under the terms of the Creative
Commons Attribution licence (http://
creativecommons.org/licenses/by/4.0), which
permits unrestricted re-use, distribution and
reproduction, provided the original article is
properly cited.We recall the life and work of Timothy J. Crow, whose contributions provided great insights into the pathophysiology of schizophrenia and continue to shape many questions in the field. We compile his key works relating to psychotic disorders, focusing on the trajectory of his theoretical stance. Our account is interlaced with our own interpretation of the evidence that influenced Crow's arguments over the years as well as his scientific method. Crow has had a significant impact on the neuroscience of schizophrenia. Many of his observations are still valid and several questions he raised remain unanswered to date.https://www.cambridge.org/core/journals/psychological-medicine/article/seminal-contributions-of-timothy-j-crow/25B0EA70F496D0D3351937E44ADDD45
Evaluating Research Impact through Open Access to Scholarly Communication
No full textScientific research is a competitive business – in order to secure funding, promotion and tenure researchers must demonstrate their work has impact in their field. To maximise impact researchers undertake high priority research, aim to get results first, and publish in the highest impact journals. The Internet now presents a new opportunity to the scholarly author seeking higher impact: s/he can now make their work instantly accessible on the Web through author self-archiving. This growing body of open access literature (coupled with new publishing models that make journals available for-free to the reader) maximises research impact by maximising the number of people who can read it, and making it available sooner. Open access also provides a new opportunity for bibliometric research. This thesis describes the relatively recent phenomenon of open access to research literature, tools that were built to collect and analyse that literature, and the results of analyses of the effect of open access and its effect on author behaviour. It shows that articles self-archived by authors receive between 50-250% more citations, that rapid pre-printing on the Web has dramatically reduced the peak citation rate from over a year to virtually instant and how citation-impact – now widely used for evaluation – can be expanded to include a new web metric of download impact
Rewriting history : postmodern and postcolonial negotiations in the fiction of J.G. Farrell, Timothy Mo, Kazuo Ishiguro and Salman Rushdie
No full textThis thesis is a study of the rewriting of history in the work of four novelists: J. G. Farrell, Timothy Mo, Kazuo Ishiguro and Salman Rushdie. I argue that their work occupies a particular position that is both within contemporary British fiction, yet at one remove from it.
Their work is situated within the context of critiques of history that are the source of a conflict between postmodernism and postcolonialism. I suggest that each writer engages with postmodemist aesthetics often in an attempt to produce critical histones that bear witness to the voices of those hitherto silenced in conventional historiography. However, these novelists remain anxious as to the potential consequences of mobilising postmodernist models of history, particularly as to the problems this creates concerning historical reference. The thesis aims to
identify the range of related attitudes to postmodernist critiques of history at this particular juncture of contemporary fiction in English.
I approach the specific position of the novelists under study through Homi Bhabha's work on the confluence of the postmodern and the postcolonial, focusing in particular on his suggestion that the postmodem refutation of Western epistemology enables a postcolonial space where a new range of histories emerge. Because each writer works between at least two cultures, and primarily within Britain, they negotiate from within received epistemology in an attempt to locate a space at its boundaries where conventional forms of knowledge no longer have efficacy. However, in contrast to Bhabha, these writers struggle to reach this space and remain sceptical as to the usefulness of postmodernism in making available new forms of
historiography. Ultimately, their work enables a critique of current ways of theorising the relationship between the postmodem and the postcolonial in literary studies
A Note on Isomorphisms Between Canonical Frames
No full textThis paper looks at the question of what kinds of automorphisms and isomorphisms can exist within and between canonical frames for modal logics. Specifically, this paper is able to partially answer the question posed by the author in [7] of whether F L ! ¸ = F L !1 in the presence of the extra-ZFC axiom "2 ! = 2 !1 ." We answer the question in the negative for all logics below S5 and for all logics satisfying a natural condition. In addition we look at automorphisms and show that while canonical frames for S5 in particular, and logics of bounded alternative in general, have many non-standard automorphisms, the logics satisfying the aforementioned natural condition have none. A Note on Isomorphisms Between Canonical Frames Timothy J. Surendonk January 1, 1997 Abstract This paper looks at the question of what kinds of automorphisms and isomorphisms can exist within and between canonical frames for modal logics. Specifically, this paper is able to partially answer the question ..
Increasing Distributed Generation Penetration using Soft Normally-Open Points
No full textThis paper considers the effects of various voltage control solutions on facilitating an increase in allowable levels of distributed generation installation before voltage violations occur. In particular, the voltage control solution that is focused on is the implementation of `soft' normally-open points (SNOPs), a term which refers to power electronic devices installed in place of a normally-open point in a medium-voltage distribution network which allows for control of real and reactive power flows between each end point of its installation sites. While other benefits of SNOP installation are discussed, the intent of this paper is to determine whether SNOPs are a viable alternative to other voltage control strategies for this particular application. As such, the SNOPs ability to affect the voltage profile along feeders within a distribution system is focused on with other voltage control options used for comparative purposes. Results from studies on multiple network models with varying topologies are presented and a case study which considers economic benefits of increasing feasible DG penetration is also given
Uncertainty and the price for crude oil reserves
No full textInnovations in futures, options, and derivative instruments permit active trading, speculating and hedging - linking markets for physical petroleum products with financial markets. These derivative markets continuously value petroleum delivered today and for future dates, providing a market price for inventories. Underground petroleum reserves are also an inventory defined by exploration surveys and development drilling. Thus, observable market information can be used to value these reserves. Option - valuation models can be used to price reserves using observable markets, but are dependent on unexplained convenience yields revealed by the term structure of futures prices. The authors apply a general inventory pricing model to petroleum inventories and generate an empirical model of the returns to storage for petroleum markets. They examine the determinants of the crude oil convenience yield using a stochastic control model. They specify optimal production and inventory conditions using a third-order cost function and estimate them using monthly observations. Their inventory arbitrage condition embodies the Hotelling principle and Kaldor's convenience yield, and includes a premium on the dispersion in crude oil prices. The empirical results suggest that returns to storage contain both a cost-reducing component and often sizable premiums associated with the dispersion of petroleum prices. Their findings suggest that crude oil markets differentiated by quality and location provide similar premiums. The premiums associated with the dispersion of petroleum prices may account for persistent backwardation in crude oil prices. This finding may also explain the wide discrepancies between Hotelling values and transaction prices found in previous studies.Economic Theory&Research,Environmental Economics&Policies,Markets and Market Access,Labor Policies,Payment Systems&Infrastructure,Oil Refining&Gas Industry,Environmental Economics&Policies,Access to Markets,Markets and Market Access,Economic Theory&Research
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire
No full textThe majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire
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