13,159 research outputs found

    Dataset for Flexible Mid-IR fiber bundle for thermal imaging of inaccessible areas

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    This dataset supports the publication: Andrea Ventura, Fedia Ben Slimen, Joris Lousteau, Nicholas White, Ali Masoudi, Petr Janicek, and Francesco Poletti Flexible Mid-IR fiber bundle for thermal imaging of inaccessible areas Optics Express</span

    Interview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American City

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    Interview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American Cit

    Resurrecting the Author

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    Presentation of Nicholas Wolterstorff\u27s Paper Resurrecting the Author with time after for questions beginning at 18:00

    Transcript: Ben Calf Robe and One Gun

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    One Gun/Nitai’namika – Blackfoot (Siksika): Born in 1884, One Gun is an abbreviation of Taking One Gun. He was the son of Owl Child and grandson of The Sun, a famous warrior chief. One Gun established his farm in 1912 and was a successful cattle owner. He enjoyed taking part in ceremonial life, where along with his wife, he sponsored five Sun Dances. He also owned three medicine pipes and was a member of the Horn Society. He attended the Calgary Stampede from its beginnings in 1912, where his teepee was well-known. He died in 1973, after serving 30 years as a member of the Tribal Council. Nicholas de Grandmaison sketched his portrait in 1942 and in 1953.The University of Lethbridge Library received permission from the University of Lethbridge Archives and the Dr. Margaret (Marmie) Perkins Hess Gallery to digitize and display this content

    Ben Calf Robe and One Gun

    No full text
    One Gun/Nitai'namika - Blackfoot (Siksika): Born in 1884, One Gun is an abbreviation of Taking One Gun. He was the son of Owl Child and grandson of The Sun, a famous warrior chief. One Gun established his farm in 1912 and was a successful cattle owner. He enjoyed taking part in ceremonial life, where along with his wife, he sponsored five Sun Dances. He also owned three medicine pipes and was a member of the Horn Society. He attended the Calgary Stampede from its beginnings in 1912, where his teepee was well-known. He died in 1973, after serving 30 years as a member of the Tribal Council. Nicholas de Grandmaison sketched his portrait in 1942 and in 1953.The University of Lethbridge Library received permission from the University of Lethbridge Archives and the Dr. Margaret (Marmie) Perkins Hess Gallery to digitize and display this content.Ye

    Induced sputum: a window to lung pathology

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    Sputum is recognized as a sampling method for the monitoring and assessment of chronic lung diseases such as asthma, COPD (chronic obstructive pulmonary disease) and cystic fibrosis. Sputum samples the central airways and its protein components (e.g. mucins and cytokines), cellular components (e.g. eosinophils and neutrophils) and microbiological components (e.g. viruses and bacteria) can be used as markers of disease severity, exacerbation, susceptibility or progression. This paper describes the basic constituents of induced sputum and how these influence the quantification and identification of novel biomarkers of chronic lung diseases using techniques such as proteomics.<br/

    What do cancer-specific CD8+ T cells see?: the contribution of immunopeptidomics

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    Immunopeptidomics is the survey of all peptides displayed on a cell or tissue when bound to human leukocyte antigen (HLA) molecules using tandem mass spectrometry. When attempting to determine the targets of tumour-specific CD8+ T cells, a survey of the potential ligands in tumour tissues is invaluable, and, in comparison with in-silico predictions, provides greater certainty of the existence of individual epitopes, as immunopeptidomics-confirmed CD8+ T-cell epitopes are known to be immunogenic, and direct observation should avoid the risk of autoreactivity which could arise following immunisation with structural homologues. The canonical sources of CD8+ T-cell tumour specific epitopes, such as tumour associated antigens, may be well conserved between patients and tumour types, but are often only weakly immunogenic. Direct observation of tumour-specific neoantigens by immunopeptidomics is rare, although valuable. Thus, there has been increasing interest in the non-canonical origins of tumour-reactive CD8+ T-cell epitopes, such as those arising from proteasomal splicing events, translational/turnover defects and alternative open reading frame reads. Such epitopes can be identified in silico, although validation is more challenging. Non-self CD8+ T-cell epitopes such as viral epitopes may be useful in certain cancer types with known viral origins, however these have been relatively unexplored with immunopeptidomics to date, possibly due to the paucity of source viral proteins in tumour tissues. This review examines the latest evidence for canonical, non-canonical and non-human CD8+ T-cell epitopes identified by immunopeptidomics, and concludes that the relative contribution for each of these sources to anti-tumour CD8+ T-cell reactivity is currently uncertain.</p

    Ben Calf Robe and One Gun (longer version)

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    One Gun/Nitai'namika - Blackfoot (Siksika): Born in 1884, One Gun is an abbreviation of Taking One Gun. He was the son of Owl Child and grandson of The Sun, a famous warrior chief. One Gun established his farm in 1912 and was a successful cattle owner. He enjoyed taking part in ceremonial life, where along with his wife, he sponsored five Sun Dances. He also owned three medicine pipes and was a member of the Horn Society. He attended the Calgary Stampede from its beginnings in 1912, where his teepee was well-known. He died in 1973, after serving 30 years as a member of the Tribal Council. Nicholas de Grandmaison sketched his portrait in 1942 and in 1953.The University of Lethbridge Library received permission from the University of Lethbridge Archives and the Dr. Margaret (Marmie) Perkins Hess Gallery to digitize and display this content.Not yet availabl

    Heritability and Linkage Analysis of Appendicitis Utilizing Age at Onset

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    Appendicitis usually afflicts the young, but there is a large tail in the distribution of onset age. The genetics of this disease are still not well understood. A heritability analysis and genome wide linkage analysis of a large twin dataset was undertaken. Treating age of onset of appendicitis as a censored survival trait revealed a heritability of 0.21, and found evidence of linkage to Chromosome 1p37.3. Author(s): Christopher Oldmeadow 1 * | Kerrie Mengersen 2 | Nicholas Martin 3 | David L. Duffy
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