1,721,042 research outputs found
Pachydermodactyly--just a sign of emotional distress
Pachydermodactyly (PDD) is a benign, asymptomatic soft tissue swelling affecting the skin of the lateral aspects of the proximal interphalangeal joints of the fingers II-IV, mostly in young adolescent males, and could be interpreted as a consequence of tic-like behaviour as an obsessive-compulsive disorder in male adolescents. The differential diagnosis includes numerous diseases; a rapid clinical recognition of PDD would avoid many useless and expensive diagnostic tests. There is no effective medical treatment for PDD, but discontinuation of the tic-like mechanical traumatisation generally leads to a marked amelioration of the finger swelling. In this article we review the world literature, which contains 87 additional cases on this topic
Acquired partial lipodystrophy (Barraquer-Simons Syndrome) associated with chronic discoid lupus erythematosus
Histological review of skin cancers in persons with albinism living in Tanzania: A 10 year retrospective study
Septic mucormycosis in acute t-cell leucemia – pathogen detection in skin lesions
We report on a 43-year old patient with an acute
T-Cell Leucemia, currently in Aplasia after Chemotherapy,
showing five targetoid bluish skin lesions.
Due to a three weeks history of septic symptoms he
was under treatment with antibiotics and antifungals.
Multiple septic foci were localized (N. caudatus,
liver, kidneys, lung, spine and right psoas). Microbiology
analyses of various blood cultures and
of the aspirate of the psoas abscess showed initially
negative results. Clinically the skin lesions were suspected
to be of septic or thrombogenic origin. A
5 mm punch biopsy was performed and separated
for microbiological diagnostic and conventional histology.
Surprisingly large fungal agents in mostly intravascular
distribution were seen histologically and
identified as Lichtheimia corymbifera (syn. Absidia
corymbifera) by PCR. Cultures remained negative.
The patient died on the following day.
Lichtheimia corymbifera is a fungus belonging to
the family of mucormycosis. Aspergillosis and mucormycosis
are the most common mold infections
in patients with hematological malignancies, clinically
often indistinguishable. However, the true incidence
of mucormycosis is not known and probably
underestimated because of difficulties in diagnosis.
Mucormycosis typically causes acute, aggressive,
and frequently angioinvasive infections presenting
with solitary local skin necrosis. The fact that the
pathogenic fungus was isolated from a very discrete
skin lesion but was not detected in blood cultures,
and only later in the PCR of the aspirate of the psoas
abscess, makes this case exceptional
Urgent consultations at the dermatology department of Basel University Hospital, Switzerland: characterisation of patients and setting - a 12-month study with 2,222 patients data and review of the literature.
BACKGROUND
Urgent consultations for skin disorders are commonly done in different settings. Scarce data exist about the characteristics of these patients.
OBJECTIVE
The aim of this study was to analyse specific characteristics of patients receiving an urgent consultation at a dermatology department in a university hospital.
METHODS
We prospectively recorded the data of all patients having had an urgent consultation during a period of 12 months.
RESULTS
We registered 2,222 urgent consultations. The most frequent diagnoses were eczemas (24.8%), dermatomycoses (5.1%) and dermatitis not otherwise specified (4.8%). The most frequent treatments were topical steroids, emollients, topical antibiotics, systemic antihistamines, antibiotics and virostatics. 2.2% of patients were hospitalized, 78.8% asked for a consultation for a disease lasting less than 4 weeks, and 6.9% presented the same day as the skin disease appeared.
CONCLUSIONS
This study shows the characteristics of patients receiving an urgent dermatologic consultation. It underlines the need for collaboration between dermatologists, other physicians, general practitioners and nurses
Definition of terms describing histopathological characteristics of stromal changes. What are exactly scar, fibrosis, fibroplasia, sclerosis, regression, desmoplasia. Do we mean all the same? Do we see all the same things?
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