47,118 research outputs found
Supplemental Material, 833839_Appendix_E - Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury
No full textSupplemental Material, 833839_Appendix_E for Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury by Lisa L. Engel, Dorcas E. Beaton, Robin E. Green and Deirdre R. Dawson in Canadian Journal of Occupational Therapy</p
Supplemental Material, 833839_Appendix_B - Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury
No full textSupplemental Material, 833839_Appendix_B for Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury by Lisa L. Engel, Dorcas E. Beaton, Robin E. Green and Deirdre R. Dawson in Canadian Journal of Occupational Therapy</p
Supplemental Material, 833839_Appendix_D - Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury
No full textSupplemental Material, 833839_Appendix_D for Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury by Lisa L. Engel, Dorcas E. Beaton, Robin E. Green and Deirdre R. Dawson in Canadian Journal of Occupational Therapy</p
Supplemental Material, 833839_Appendix_C - Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury
No full textSupplemental Material, 833839_Appendix_C for Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury by Lisa L. Engel, Dorcas E. Beaton, Robin E. Green and Deirdre R. Dawson in Canadian Journal of Occupational Therapy</p
Supplemental Material, 833839_Appendix_A - Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury
No full textSupplemental Material, 833839_Appendix_A for Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury by Lisa L. Engel, Dorcas E. Beaton, Robin E. Green and Deirdre R. Dawson in Canadian Journal of Occupational Therapy</p
Schooling and education.
No full textSchooling and education by Giles R. Wright with Howard L. Green and Lee R. Parks. Number 4 in the New Jersey Ethnic Life Series. Published by New Jersey Historical Commission
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
De Maiestate / Praeside M. Jacobo Thomasio, Moralis Philosoph. P. P., publice disputabit Johannes Dunte, R. L. Author & Respon: ad diem 9. Septembr. H L. Q. C.
No full textDE MAIESTATE / PRAESIDE M. JACOBO THOMASIO, MORALIS PHILOSOPH. P. P., PUBLICE DISPUTABIT JOHANNES DUNTE, R. L. AUTHOR & RESPON: AD DIEM 9. SEPTEMBR. H L. Q. C.
De Maiestate / Praeside M. Jacobo Thomasio, Moralis Philosoph. P. P., publice disputabit Johannes Dunte, R. L. Author & Respon: ad diem 9. Septembr. H L. Q. C. (1)
Titelblatt (1)
Widmung (2)
Text (3)
Beiträge (21
Antibody array characterization of inflammatory mediators in allergic and normal tears in the open and closed eye environments
No full textTo evaluate the use of stationary phase protein array technology for tear analysis and to characterize the distribution of inflammatory mediators in normal and allergic tears in the open and closed eye states. Microcapillary tube collected Open (OTF) and closed eye tear fluid (CTF) samples from normals (N), from individuals with various active chronic ocular and other allergies (CA), as well as from an individual subsequent to unilateral induction of an acute allergic conjunctivitis were assayed using membrane arrays that were optimized to allow the detection of GM-CSF, ILs-1 alpha, 1 beta, 2-10, 12-13, INF gamma, MCP-1 and TNFalpha in clinical size samples. The protocol of a micro-well plate array specific for ILs-2, 4, 5, 8, 10, 12, 13, TNFalpha and INF gamma was modified to minimize the impact of tear matrix effects. This was used to carry out parallel analysis on selected samples. By optimizing the protocol as well as the composition of a membrane array it proved possible to significantly increase the signal-to-noise ratio and sensitivity of assay allowing for the detection of some inflammatory mediators into the sub-picogram range. This provided sufficient sensitivity to allow the assay of clinically obtainable size samples. Analysis revealed that OTF from most Ns contained a high level of IL-8 and faint signals if any for the other probed proteins. In contrast, OTF samples from most CA individuals with and without ocular symptoms exhibited to varying degrees detectable levels of most of the other probed entities. The difference between normal and pathological tears and the levels of signals became far more pronounced in the CTF compared to the OTF samples. Use of the micro-well plate assay kit without modification revealed two tear matrix effects that profoundly impact the ability to obtain meaningful ELISA data. Modifying the assay protocol reduces but does not eliminate these artifacts making it possible to approximate the concentration of many of the probed entities. The obtained data is consistent using both methodologies revealing elevated levels of IL-8 and other cytokines in approximately 60% of the OTF samples from the CA population. Other than a modest increase in IL-8, no change could be observed in the profile of OTF after induction of an acute allergic reaction
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
- …
