2,655 research outputs found
Neutralising antibody responses in cattle and sheep following booster vaccination with two commercial inactivated bluetongue virus serotype 8 vaccines
No full textCattle and sheep that had received a primary course of vaccination with an inactivated bluetongue virus serotype 8 (BTV-8) vaccine were booster vaccinated 6 or 12 months later with the homologous vaccine or an alternative inactivated BTV-8 vaccine and neutralising antibody responses were determined. Antibody titres to the alternative vaccine were significantly higher than to the homologous vaccine (P = 0.013) in cattle. There was no significant difference between the antibody responses to alternative and homologous vaccines in sheep. These data indicate that cattle and sheep primed with one inactivated BTV-8 vaccine may be effectively boosted with an alternative commercial inactivated BTV-8 vacci
C.A. Parker's Store
No full textPhotograph - A dog team and a loaded sled on Strathcona Street in front of C.A. Parker's store, Athabasca, Albert
Eigen schuld van de architect
No full textRede, uitgesproken bij het afscheid als buitengewoon hoogleraar in het bouw- en woning recht aan de Technische Hogeschool Delft op vrijdag 21 februari 1986 door prof.mr C.A. Adriaansens.Architectur
Determinación de los riesgos financieros beta para las empresas ecuatorianas: caso Supermercados La Favorita C.A.
No full textProyecto desarrollado para determinar una aproximación real del riesgo financiero de la empresa Supermercados La Favorita C.A., para ello se procede a evaluar de manera estadística un modelo CAPM simple con el programa estadístico E-Views que analiza las distintas variables y modelos, finalmente se evalúa los resultados que se obtienen para poder determinar si el modelo de valoración CAPM simple es un buen indicador para determinar riesgo financiero de Supermercados La Favorita C.A.; este modelo estadístico es de suma ayuda se puede aprobar para determinación de riesgo de las empresas del entorno ecuatoriano.GuayaquilEconomista con mención en Gestión Empresaria
C.A. McGill, March 23, 1918
No full textPortrait of C.A. McGill. Written on verso: With love from C.A. McGill Monrovia, Liberia, March 23rd, 1918.The Atlanta University Center Robert W. Woodruff Library acknowledges the generous support of the National Endowment for Humanities - Humanities Collections and Reference Resources Implementation Project Grant in supporting the processing and digitization of a number of its major archival collections as part of the project: Spreading the Word: Expanding Access to African American Religious Archival Collections at the Atlanta University Center Robert W. Woodruff Library.</em
Determinación de los riesgos financieros beta para las empresas ecuatorianas: caso supermercados la favorita c.a
No full textEl objetivo principal de este proyecto es determinar una aproximación real del riesgo financiero de la empresa Supermercados La Favorita C.A. Para esto se utilizó como primer modelo al CAPM para medir el riesgo de la empresa basándonos en el precio de las acciones desde el año 2002 al 2006.
Luego de esto se desarrolló un modelo más amplio en el cual se introdujeron variables macroeconómicas que podrían explicar mejor el riesgo financiero de la empresa, estas variables son :la tasa activa, importaciones, inflación, IDEAC y Salario.
La evaluación estadística de estas variables se las realizó en el programa estadístico E-Views y en base a estos resultados se determinó que para el modelo CAPM simple el índice que mejor explica el riesgo financiero es el IPECU.
Dado estos resultados podemos concluir que el modelo CAPM simple es una buena herramienta para la estimación del riesgo financiero pero no es completa debido a que solo considera una variable explicativ
Erratum: Future temperature extremes will be more harmful: A new critical factor for improved forecasts (Int. J. Environ. Res. Public Health 2019, 16 (20), 4015)
No full textThe authors would like to correct the names and surnames of both authors of their previous paper [1] as follows: Costas A. Varotsos1,2,* and Yuri A. Mazei2 Therefore, to cite this paper please use the correct reference as follows: Varotsos, C.A.; Mazei,Y.A. Future Temperature Extremes Will Be More Harmful: A New Critical Factor for Improved Forecasts. Int. J. Environ. Res. Public Health 2019, 16 (20), 4015. © 2020 by the author. Licensee MDPI, Basel, Switzerland
Skeleton-based design and simulation flow for Computation-in-Memory architectures
No full textMemristor-based Computation-in-Memory is one of the emerging architectures proposed to deal with Big Data problems. The design of such architectures requires a radically new automatic design flow because the memristor is a passive device that uses resistance to encode its logic value. This paper proposes a design flow for mapping parallel algorithms on the CIM architecture. Algorithms with similar data flow graphs can be mapped on the crossbar using the same template containing scheduling, placement, and routing information; this template is named skeleton. By configuring such a skeleton with different pre-designed circuits, we can build CIM implementations of the corresponding algorithms in that class. This approach does not only map an algorithm on a memristor crossbar, but also gives an estimation of its performance, area, and energy consumption. It also supports user-defined constraints and parallel SystemC simulation. Experimental results demonstrate the feasibility and the potential of the approach.Accepted Author ManuscriptComputer EngineeringQuantum & Computer EngineeringFTQC/Bertels La
Thoughts about cancer stem cells in solid tumors
No full textCancer chemotherapy efficacy is frequently impaired by either intrinsic or acquired tumor resistance. A fundamental problem in cancer research is identifying the cell type that is capable of sustaining neoplastic growth and its origin from normal tissue cells. In recent years, the cancer stem cell (CSC) theory has changed the classical view of tumor growth and therefore the therapeutic perspective. Overcoming intrinsic and acquired resistance of cancer stem/progenitor cells to current clinical treatments represents a major challenge in treating and curing the most aggressive and metastatic cancers. On the other hand, the identification of CSCs in vivo and in vitro relies on specific surface markers that should allow the sorting cancer cells into phenotypically distinct subpopulations. In the present review, recent papers published on CSCs in solid tumors (breast, prostate, brain and melanoma) are discussed, highlighting critical points such as the choice of markers to sort CSCs and mouse models to demonstrate that CSCs are able to replicate the original tumor. A discussion of the possible role of aldehyde dehydrogenase and CXCR6 biomarkers as signaling molecules in CSCs and normal stem cells is also discussed. The author believes that efforts have to be made to investigate the functional and biological properties of putative CSCs in cancer. Developing diagnostic/prognostic tools to follow cancer development is also a challenge. In this connection it would be useful to develop a multidisciplinary approach combining mathematics, physics and biology which merges experimental approaches and theory. Biological models alone are probably unable to resolve the problem completely
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