6 research outputs found

    “Tevarikh-i Desht-i Kipchak” as a Source of Historical Geography of the Crimean Khanate and Adjacent Territories

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    Research objectives: To conduct a comprehensive historical and geogra­phical analysis of the work of Abdullah Ibn Rizvan. Research materials: The author used the chronicle of Abdullah Ibn Rizvan as well as specialized scholarly works on the sources and history of the Crimean Khanate. Results and novelty of the research: The “Tevarikh-i Desht-i Kipchak” (Chronicles of Desht-i Kipchak) by Abdullah Ibn Rizvan is still a poorly studied historical source as it has not been translated into Russian. The work has been preserved in two manuscripts: the French National Library in Paris and the Topkapi Palace in Istanbul. In 1966, Adam Zajączkowski published the “Tevarikh-i Desht-i Kipchak” in Warsaw based on the Istanbul manuscript in comparison with the Paris manuscript. A Polish orientalist added a 1737 French translation of the annals by Pierre Delaunay entitled “Abrégé de l’histoire des quatorze premiers khans”. We used this French translation from the Warsaw edition of Adam Zajączkowski. Researchers practically neglected studying the abundant information of the chronicle on the political history of the Crimean Khanate in the first third of the seventeenth century, as well as on the historical geography of the Crimean Khanate and the entire area of the Kipchak steppe. Since his father was the governor of Kefe, Abdullah knew this area well, receiving the relevant firsthand information. Based on a comprehensive historical and geographical analysis of the chronicle, we can state that despite errors in the history of the Golden Horde and the Crimean Khanate the author was well acquainted with the events that took place in Crimea in 1610, as well as with the geography of the surroundings of Kefe, if not the whole Crimean peninsula. Abdullah mentioned such geographical places as Sarygol and Pasha Tepe. He described in detail two battles between Rizvan Pasha and Muhammad Giray, being a likely eyewitness to the events or basing his account on the oral information of participants including his father

    Designing a Forex Trading and Equity Investment Strategy for the New-State Capital Hedge Fund

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    Construct the investment strategy for the New-State Capital Hedge Fund. Identify profit making opportunities in Foreign Exchange (Forex) & Equities using both conventional and non-conventional indicators. The author is to articulate and document his current knowledge in the chosen area in order to stimuate ideas in creating potential investment strategies. Justify knowledge with actual results in a genuine live investment. Critique and evluate the effectiveness of the proposed investment strategy. Conclude with lessons learned and future research

    The role of the liturgy in the process of evangelizing

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    Otkrivajući važnost nove evangelizacije u poslanju Crkve, autor u svojem radu nastoji prikazati ulogu liturgije u samom procesu evangelizacijskog djelovanja. Slijedeći misao pape Benedikta XVI. izrečenu u dokumentu osnutka Vijeća za novu evangelizaciju Ubicumque et semper, autor pokušava pronaći mjesto liturgiji i njezinu teološkom izričaju koji predstavlja svojevrsni kompendij oživotvorenja nove evangelizacije. Tako kroz pojedine neuralgične točke s kojima se susreće proces nove evangelizacije, poput modernog shvaćanja vremena, sekularizma koji mijenja značenjsku vrijednost obrednosti, kulturološkog i sociološkog aspekta asimilacije suvremenog društva, problema gubitka osjećaja za sveto, infantilizma vjere, autor prepoznaje liturgiju kao iskustveni odgovor na suvremena traženja i kao trajni korektiv poslanja nove evangelizacije. Zbilja po kojoj postajemo dionici Kristova djela spasenja omogućuje nam i svježinu koraka u navještaju evangelizacijskog pologa.Bringing to light the importance of New Evangelization in the Church’s mission today, the author endeavors in his work to outline the role of the liturgy in the process of evangelizing in a new way. A process that grasps the entire theological thought is also essential for the theology of the liturgy which recognizes in the presence of Christ’s Easter Mystery the necessary backbone for such an evangelistic elan. Following the thought of pope Benedict XVI expressed in the document establishing the Council for promoting the New Evangelization Ubicumque et semper, the author seeks to find a place for liturgy and its theological expression which represents a unique compendium for the accomplishment of the New Evangelization. Through some sore points met in the process of New Evangelization, such as the modern understanding of the times, secularism which modifies the significance of ritual, cultural and social aspects of the assimilation of the contemporary society, the problem of loss of feeling for the holy, the infantilization of faith, the author recognizes liturgy as a tried out answer to the contemporary searchs and as a perpetual remedy for the mission of New Evangelization. The reality by which we truly become participant of the Christ’s saving deed gives us a freshness of step in the announcement of the evangelistical deposit

    PSO based approach for scheduling NPD projects including overlapping process

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    The efficient scheduling of the new product development (NPD) projects is important to reduce the required development time, and to offer the new product faster. Activity overlapping is commonly regarded as the most promising strategy to reduce product development times. However, overlapping must be well-planned by weighting the gain from the activity overlapping against the additional time for rework. The objective of this research was to develop a resource constrained scheduling methodology for NPD projects considering overlapping of activity couples. A particle swarm optimization based approach is used to schedule NPD projects that include overlapping process. The proposed PSO method is developed into a user friendly system so that the practitioners can utilize it. A real-life example of a product development project taken from the literature is used to show the efficiency of the software. (C) 2015 Elsevier Ltd. All rights reserved.Scientific and Technological Research Council of Turkey TUBITAKThe corresponding author is grateful to The Scientific and Technological Research Council of Turkey TUBITAK for supporting her scientific studies

    Hemp-Derived Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Characterization, and Therapeutic Potential

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    Iron oxide nanoparticles (IONPs) have emerged as the most widely synthesized metal nanoparticles in sustainable chemistry due to their unique magnetic properties, excellent biocompatibility, biodegradability, and non-toxicity. In this study, IONPs are successfully synthesized via a rapid, sustainable, and environmentally friendly green synthesis approach using Cannabis sativa L. leaf extract. X-ray diffraction analysis determined that the synthesized NPs had an average particle size of 18.8 nm, while transmission electron microscopy images reveal a spherical morphology with sizes ranging from 12 to 21 nm. Fourier-transform infrared spectroscopy analysis confirmed the presence of cannabinoids, terpenoids, and flavonoids, which are believed to play a crucial role in the formation and stabilization of IONPs. Its photocatalytic potential is demonstrated through the degradation of bromophenol blue dye. Additionally, the NPs exhibited significant antibacterial and antifungal activity against various microbial species, along with promising anticancer effects on cancer cell lines. In conclusion, this study provides a promising foundation for advancing the large-scale, commercial production of IONPs through green synthesis methods. By offering an eco-friendly and efficient alternative to conventional nanoparticle synthesis, the findings contribute significantly to the growing body of research in sustainable nanotechnology.TUBIdot;TAK [2209-A-1919B012002782]The author would like to thank TUB & Idot;TAK (Grant 2209-A-1919B012002782) for financial support and Samet Kaya, a student of Yozgat Bozok University Faculty of Science, Department of Molecular Biology and Genetics, for helping with synthesis studies

    Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

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    SummaryBackground Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatoryactions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospitalwith COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients wererandomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once perday by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatmentgroups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment andwere twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants andlocal study staff were not masked to the allocated treatment, but all others involved in the trial were masked to theoutcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treatpopulation. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936.Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) wereeligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomlyallocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall,561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days(rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days(rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, nosignificant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilationor death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24).Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or otherprespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restrictedto patients in whom there is a clear antimicrobial indication
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