86,681 research outputs found
Stadt-Theater Düsseldorf / Stein unter Steinen : ausser Abonnement ; Samstag, den 18. März 1916 ; Gastspiel von Albert Bassermann vom Lessingtheater Berlin ; Schauspiel in 4 Akten
No full textvon Hermann Sudermann. Spielleitung: Béla Duschak. Personen: Hans Werder, Franziska Wendt, Else Kittner, Arthur Schetter, Emil Wirth, Selma Wuttke, Kl. Agethen, O. F. Teuscher, Ludwig Mayr, Max Wogritsch, Robert Scholz, Otto Busch, Ernst Herz. Jakob Biegler: Albert Bassermann als Gas
Resultats scientifiques et pratiques destinés a la construction des machines
No full textContiene: T.I. Resultats scientifiques et pratiques destinés a la construction des machines, 1874 (XII, 533)-- T. II. Resultats scientifiques et pratiques destinés a la construction des machines : Atlas de 41 Planches, 1873 ([41]h.
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins
No full textOne component of the circadian clock in mammals is the Clock-Bmal1 heterodimeric transcription factor. Among its downstream targets, two genes, Cry1 and Cry2, encode inhibitors of the Clock-Bmal1 complex that establish a negative-feedback loop. We found that both Cry1 and Cry2 proteins are ubiquitinated and degraded via the SCF(Fbxl3) ubiquitin ligase complex. This regulation by SCF(Fbxl3) is a prerequisite for the efficient and timely reactivation of Clock-Bmal1 and the consequent expression of Per1 and Per2, two regulators of the circadian clock that display tumor suppressor activity. Silencing of Fbxl3 produced no effect in Cry1-/-;Cry2-/- cells, which shows that Fbxl3 controls clock oscillations by mediating the degradation of CRY proteins
[Newspaper Clipping: Author Claims Evidence of Second JFK Assassin #1]
No full textNewspaper article titled "Author Claims Evidence of Second JFK Assassin." The article states that author Richard J. Whalen concluded "that there is circumstantial evidence to support the theory of a second assassin in the shooting of President John F. Kennedy.
Künstlerlaunen : 33 Zeichnungen ; mit alten und neuen Gedichten / von H. Baisch, W. Diez, F. A. Kaulbach, Hugo Kauffmann, Br. Piglhein, Rud. Seitz ...
No full textKÜNSTLERLAUNEN : 33 ZEICHNUNGEN ; MIT ALTEN UND NEUEN GEDICHTEN / VON H. BAISCH, W. DIEZ, F. A. KAULBACH, HUGO KAUFFMANN, BR. PIGLHEIN, RUD. SEITZ ...
Künstlerlaunen : 33 Zeichnungen ; mit alten und neuen Gedichten / von H. Baisch, W. Diez, F. A. Kaulbach, Hugo Kauffmann, Br. Piglhein, Rud. Seitz ... (1)
Cover (1)
Titelblatt (10)
Inhalt (12)
Vorwort und Einladung (14)
Gedichte und Zeichnungen (16
JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes
No full textJHDM1B is an evolutionarily conserved and ubiquitously expressed member of the JHDM (JmjC-domain-containing his- tone demethylase) family1–3. Because it contains an F-box motif, this protein is also known as FBXL10 (ref. 4). With the use of a genome-wide RNAi screen, the JHDM1B worm orthologue (T26A5.5) was identified as a gene that regulates growth5. In the mouse, four independent screens have identified JHDM1B as a putative tumour suppressor by retroviral insertion analysis6–9. Here we identify human JHDM1B as a nucleolar protein and show that JHDM1B preferentially binds the transcribed region of ribosomal DNA to repress the transcription of ribosomal RNA genes. We also show that repression of ribosomal RNA genes by JHDM1B is dependent on its JmjC domain, which is necessary for the specific demethylation of trimethylated lysine 4 on histone H3 in the nucleolus. In agreement with the notion that ribosomal RNA synthesis and cell growth are coupled processes, we show a JmjC-domain-dependent negative effect of JHDM1B on cell size and cell proliferation. Because aberrant ribosome biogenesis and the disruption of epigenetic control mechanisms contribute to cellular transformation, these results, together with the low levels of JHDM1B expression found in aggressive brain tumours, suggest a role for JHDM1B in cancer development
Principes de la construction des organes des machines
No full textCoeditada en París Librairie Polytechnique de J. BaudryT. 1 : XIV, 459 p., 45 h. de lá
Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation
No full textThe desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters
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