2 research outputs found
INVESTIGATIVE STUDY OF THERMAL PERFORMANCE OF THERMOSYPHON SOLAR COLLECTOR
No full textExperimental and Numerical investigation has been performed to improve the thermosyphon thermal performance. Optimization process concentrated on both the water and the operating liquid temperature inside the tank and the thermosyphon. For this purpose, three different models of improvement methods have been studied that depend on increasing the surface area with no changing in the volume of operating liquid. The first one (case-A-) is by add ten ring fins about the absorber pipe. The second method (Case-B-) is by add twenty ring fins about the absorber pipe. While, the third way (Case-C-) is by add ten ring fins with ten grooves about the absorber pipe. The thermosyphon thermal performance was compared between the traditional model and experimental model. Moreover, numerical simulate for all cases were done with computational fluid dynamic (CFD), ANSYS 19.R3. It was observed through the results that a good convergence between the numerical and, experimental results. Furthermore, the thermal performance for case-A- is found greater than all other cases under study
A practical guideline to engineering nonribosomal peptide synthetases
No full textThe bioengineering of nonribosomal peptide synthetases (NRPSs) is a rapidly developing field to access natural product derivatives and new-to-nature natural products like scaffolds with changed or improved properties. However, the rational (re-)design of these often gigantic assembly-line proteins is by no means trivial and needs in-depth insights into structural flexibility, inter-domain communication, and the role of proofreading by catalytic domains-so it is not surprising that most previous rational reprogramming efforts have been met with limited success. With this practical guide, the result of nearly one decade of NRPS engineering in the Bode lab, we provide valuable insights into the strategies we have developed during this time for the successful engineering and cloning of these fascinating molecular machines. © 2023. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature
