1,327 research outputs found
D.H. Lawrence, La Volpe, traduzione e cura di Stefania Michelucci, edizione bilingue
No full textIt is the bilingual and critical edition of D.H. Lawrence's The Fox in the series, Elsinore, Collana di Classici Inglesi, edited and translated by Stefania Michelucci
The volume consists of a long introduction to the text, pp 11-37, of a biographical article on the author and his work (l'autore e l'opera), pp. 39-45), of a note to the text (pp. 47-48) (English and Italian, page to page, pp. 49-227) of explicatory notes (pp. 229-243) and of a biographical section (pp. 245-252)
Nutraceuticals in the Early Infancy
No full textAtherosclerosis disease and its extent in childhood correlate positively with established risk factors, namely obesity, hypercholesterolemia, diabetes mellitus, and hypertension. The safety and efficacy of some dietary interventions to modulate risk factors in childhood are documented by an increasing body of evidence. The present review analyzes nutritional and nutraceutical current strategies addressed to modify some risk factors of atherosclerosis in childhood. In particular, studies concerning nutrients such as fibers, omega-3-fatty acids, vitamin D, antioxidants, and calcium have been evaluated. An overall analysis suggests that some nutraceuticals might represent an attractive tool to lower the development of atherosclerotic-related cardiovascular complication in children. Nevertheless, at this moment, due to the methodological weakness that characterizes the majority of the analyzed studies, nutrients or supplements should not be considered as a therapeutic tool potentially usable for clinical purpose in children at risk for cardiovascular disease
Antiplatelet Drugs in the Management of Thrombotic/Ischemic Events in Peripheral Artery Disease
No full textPeripheral artery disease (PAD) is a problem of substantial public health importance and an important hallmark of generalized atherosclerosis involving, in particular, coronary and cerebral circulation. The risk factors for PAD are similar to the risk factors for atherosclerosis; thus, smoking should be stopped, and hypertension, diabetes mellitus, and dyslipidemia should be treated. In addition, antiplatelet therapy remains a key intervention to reduce cardiovascular risk in PAD. In patients with PAD who have clinical evidence of concomitant coronary or cerebrovascular disease, aspirin or clopidogrel would be first-line treatment. However, the data supporting the use of antiplatelet drugs in patients with PAD who do not have a history of other cardiovascular disorders are still inconclusive and further study is necessary to explore this issue
Aspirin in asymptomatic patients with a confirmed positivity of antiphospholipid antibodies
No full text[No abstract available
Letter by Violi et al regarding article, "Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization". Circulation. 2010 Aug 17;122(7):e429; author reply e430.
No full textFEATURES OF A VIRTUAL LEARNING COMMUNITY IN A BLENDED CORSE OF CLINICAL METHODOLOGY
No full textFor three years, the course of Clinical Methodology for medical students in the third year is being delivered based upon a blend of formal lessons, tutorials and online activities. Besides the availability of resources and self-evaluation tools, the online component of the course encompasses sessions of both synchronous and asynchronous discussion on easy simulations of clinical conditions and basic laboratory or EKG findings. We reviewed the transcripts of the discussion forums to look for the generic features of the virtual communities created during the course and to assess the presence of possible special characteristics of a virtual community of junior medical students. We observed the usual indicators of“social presence”like humor, interactive responses and expressions of mood and noted that social interaction was stronger about organisational topics. On the other hand, focussing on clinical topics produced a high rate of participation but with a lower interaction (i.e. shorter threads). Interaction however, when present, often assumed the traits of “peer support” and of cooperative construction of meaning.
A mechanism that proved to strongly enhance responsiveness was to avoid giving the whole clinical information at the beginning of the simulation but to split it in bits and gradually provide further elements and hints
Modeling and Sensing the Vertical Structure of the Atmospheric Path Delay by Microwave Radiometry to Correct SAR Interferograms
No full textThe vertical structure of the atmospheric water vapor induces phase errors in interferometric synthetic aperture radar (SAR) data. This paper presents a simulation study to investigate whether spaceborne submillimeter radiometric observations, which can be realized with fairly high spatial resolution, are able to derive the vertical structure of the atmospheric wet delay. The accuracy of the retrieved zenith wet delay (ZWD) trend as a function of surface height is assessed in order to correct the associated height dependence of the interferometric phase error in a SAR interferogram. Using a simulated benchmark, we evaluate the errors associated with the use of both a linear and an exponential model of the behavior of ZWD as a function of the surface height. This paper shows a fairly accurate reconstruction of the trend parameters estimated from radiometer brightness temperature images, with respect to realistic atmospheric profiles provided by radiosounding observations (RAOBs). The trend parameters that we consider in this paper are the slope K for the linear model and scale height H for the exponential one. An overall better accuracy is found for the exponential model, which is more representative of the actual behavior of ZWD with height, resulting in a residual uncertainty in the path delay due to the atmospheric stratification of approximately 0.2-0.3 cm and nearly zero bias, as compared to RAOBs
Explanatory power of gender relations in cardiovascular outcomes: the missing piece of the puzzle
No full textThe coagulopathy of chronic liver disease: Is there a causal relationship with bleeding? Yes
No full textVariceal hemorrhage is a major cause of death in patients with cirrhosis Much still could be performed in clinical practice to reduce the risk for bleeding in cirrhotic patients and accurate predictive rules should be provided for early recognition of high-risk patients Liver cirrhosis patients present a complex hemostatic dysfunction with prolongation of bleeding time, chronic coagulation activation, and secondary hyperfibrinolysis Therefore. liver failure determines an acquired coagulopathy that has been considered to be one potential underlying mechanism of bleeding Endotoxemia may play a pivotal role in activating clotting system in portal and systemic circulation and it could represent a common mechanism accounting for portal vein thrombosis, systemic hyperfibrinolysis and eventually gastrointestinal bleeding Nevertheless, clinical trials should also be planned to investigate the causal relationship between acquired coagulopathy and bleeding in patients with chronic liver disease. (C) 2010 European Federation of Internal Medicine Published by Elsevier BV All rights reserve
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