21 research outputs found
Short reverse phase HPLC method for 5-methoxy-2-mercaptobenzimidazole related substance estimation
No full textMicrowave-assisted solution phase synthesis of novel pyridine carboxamides in neat water and ADMET and protein-compounds interaction analysis and antibacterial activity
No full text99-106A range of novel 5-substituted-pyridine-2-carboxamides have been designed and synthesized by microwave-assisted
solution phase synthesis in neat water. Their structures have been confirmed by 1H NMR, 13C NMR and LCMS analysis.
The present work describes a simple, rapid, and efficient synthesis of compound 2a-2h in good yield under mild reaction
condition. Shorter reaction time and convenient workup make this methodology more practical. This protocol proceeds
smoothly and avoids the use of toxic organic solvents. ADMET analysis have been performed for all the synthesized
compounds and observed that all the eight compounds taken for the investigation have been shown to satisfy Lipinski's rule
of 5. The molecular interaction study is performed using the AutoDock software. All the 8 test compounds are found to have
higher binding affinity than the control compound chloramphenicol to the E. Coli DraE adhesion. In addition antibacterial
activities of all eight compounds have been determined
Kinetic, Thermodynamic and Adsorption Isotherms Studies on Removal of Copper(II) Ions from Aqueous Solutions Using Jumbo Grass (Sorghum Bicolur Sorghum Sudanefe)
No full textA facile synthesis of novel 5‐substituted pyridine 2 carboxamide derivatives and their biological evaluation and 3D QSAR studies
No full textSynthesis and Characterization of Methacrylate-Based Antibacterial Copolymers for Anticorrosive Application
No full textMicrobial Screening of Thermally stable N-Vinyl Carbazole-co-Methoxyethyl methacrylate Copolymers: Synthesis and Characterization
No full textSynthesis, characterization and corrosion protection properties of poly(N-vinyl carbazole-co-glycidyl methacrylate) coatings on low nickel stainless steel
No full text
Photostable electroactive polymer based nanocomposite films for the protection of mild steel from corrosion
No full textCopolymers of phenoxyethyl methacrylate with glycidyl methacrylate: Synthesis, characterization and reactivity ratios
Get PDFThe free radical copolymerization of phenoxyethyl methacrylate (POEMA) and glycidyl methacrylate (GMA) was carried out using ,'-azobisisobutyronitrile (AIBN) in 2-butanone solution at 3331K. The copolymers were characterized by FTIR, 1H-NMR and 13C-NMR spectroscopic methods. Thermal properties of the copolymers were also studied by thermogravimetric analysis (TGA). The compositions of the copolymers were established by 1H-NMR analysis. The monomer reactivity ratios were computed using the Fineman-Ross (F-R) and Kelen-Tdos (K-T) methods. These parameters were also estimated using a nonlinear computational fitting procedure, known as reactivity ratios error in variable model (RREVM). The mean sequence lengths determination indicates that the copolymers obtained are random in nature. Differences in the reactivity ratios obtained by the classical methods and RREVM were observed. GMA is more reactive than POEMA and although the copolymers are random, some tendency to GMA small block format
