1,721,185 research outputs found
Chlamydia trachomatis versus common uropathogens as a cause of chronic bacterial prostatitis: is there any difference? Results of a prospective parallel cohort study.
Full text linkPurpose: The role of Chlamydia trachomatis (CT) infection in chronic bacterial prostatitis (CBP) is well known. What is unclear is
whether there are any differences in the course or clinical outcome of the disease when the cause is CT or other uropathogens.
Materials and Methods: A series of 311 patients affected by CBP due to CT (cohort A) was compared with a group of 524 patients
affected by CBP caused by common uropathogen bacteria (cohort B). All participants completed the following questionnaires: National
Institutes of Health Chronic Prostatitis Symptom Index, International Prostate Symptom Score, International Index of Erectile
Function-15 erectile function domain (IIEF-15-EFD), Premature Ejaculation Diagnostic Tool (PEDT), and the Short Form 36 (SF-36)
Health Survey. All patients were followed with clinical and microbiological evaluations.
Results: After a mean follow-up time of 42.3 months, the number of symptomatic episodes was significantly higher in patients in
cohort A than in cohort B (4.1±1.1 vs. 2.8±0.8, p<0.001), and the mean time to first symptomatic recurrence was shorter in cohort
A than in cohort B (3.3±2.3 months vs. 5.7±1.9 months, p<0.001). Moreover, scores on the SF-36 tool were significantly lower in
cohort A (96.5±1.0 vs. 99.7±1.9, p<0.001) at the first symptomatic recurrence. Cohort A also showed significantly lower scores on
the IIEF-15-EFD and PEDT questionnaires at the end of the follow-up period (26.8±2.9 vs. 27.3±3.3, p=0.02 and 11.5±2.3 vs. 4.5±2.8,
p<0.001, respectively).
Conclusions: Patients affected by CBP due to CT infection have a higher number of symptomatic recurrences with a more severe
impact on quality of life
A case series of patients who underwent laparoscopic extraperitoneal radical prostatectomy with the simultaneous implant of a penile prosthesis: focus on penile lenght preservation
Full text linkPurpose: There are many grey areas in the field of penile rehabilitation after radical prostatectomy (RP). The preservation of
the full dimensions of the penis is an important consideration for improving patients’ compliance for the treatment. We present
the first case series of patients treated by laparoscopic extraperitoneal RP and simultaneous penile prosthesis implantation
(PPI) in order to preserve the full length of the penis and to improve patients’ satisfaction.
Materials and Methods: From June 2013 to June 2014, 10 patients underwent simultaneous PPI (with an AMS InhibiZone
prosthesis) and RP. Patients were evaluated by means of urological visits, questionnaires, and objective measurements before
surgery, at discharge from the hospital, on postoperative days 21 to 28, each 3 months for the first year, and each 6 months
thereafter. The main outcome measures were biochemical recurrence-free rate, penile length, and quality of life.
Results: Ten patients (mean age of 61 years; completed the study follow-up period (median, 32.2 months). No difference was
found between the time of surgery and the 2-year follow-up evaluation in terms of penile length. The pre-surgery 36-Item
Short Form Health Survey (SF-36) median score was 97. Patients were satisfied with their penile implants, and couples’ level
of sexual satisfaction was rated median 8. The median postoperative SF-36 score was 99 at 3 months follow-up.
Conclusions: Laparoscopic extraperitoneal RP surgery with simultaneous PPI placement seems to be an interesting possibility
to propose to motivated patients for preserving the length of the penis and improving their satisfaction
How to use antimicrobial prophylaxis in urological procedures
Full text linkAntimicrobial prophylaxis is effective in a wide range of
urological procedures and has contributed to reduce the rate
of postoperative infectious complications [1]. Adherence to
European Association of Urology (EAU) guidelines on
antimicrobial prophylaxis reduces antimicrobial usage
without increasing postoperative infection rates, lowers
the prevalence of resistant uropathogens, and saves costs [2].
Nevertheless, adherence to EAU guidelines is not optimal.
Antimicrobials are used for clean procedures without
evidence and the types of antimicrobials used are not
according to guidelines recommendations [3]. Also, antimi-
crobial prophylaxis is often extended beyond the recom-
mended 24-h period with important consequences such as
appearance of multi-resistant organisms, including strains
resistant to newer agents, worsened clinical outcome, and
increased treatment costs [2]. Patients as well as the hospital
ecology are unnecessary exposed to broad-spectrum anti-
microbials and their adverse effects. It is of outmost
importance to preserve the arsenal of effective antimicrobials
at a hospital level and even beyond the hospital. A revision of
clinical practice in terms of antimicrobial prophylaxis is
urgently needed. The correct use of antimicrobial prophy-
laxis in urological procedures rests on three pillars: (1)
knowledge of the local pathogen profile and antimicrobial
resistance, (2) careful evaluation of patient-related risk
factors for the development of infectious complications after
urological procedures, and (3) adherence to EAU guidelines
on urological infections. This clinical consultation guide aims
to give a short update on evidence-based recommendations
Transurethral resection of the prostate biopsy of suspected anterior prostate cancers identified by multiparametric magnetic resonance imaging: a pilot study of a novel technique. Editorial Comment
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La obsolescencia programada como asunto controvertido. Un análisis del debate público online en torno a la salida de los dispositivos Apple
No full textLa obsolescencia programada como asunto controvertido. Un análisis del debate público online en torno a la salida de los dispositivos Apple
No full textAnalisi della controversia relativa alla obsolescenza programmata in relazione alla critica alla società dei consum
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