49 research outputs found
Case report: a severe hypernatremia with multiple organ failure, about a clinical observation
No full textCase Report: A Severe Hypernatremia with Multiple Organ Failure, about a Clinical Observation
No full textEmerg Infect Dis
No full textAfter a period of heavy rainfall, an outbreak of Rift Valley fever occurred in southern Mauritania during September-November 2012. A total of 41 human cases were confirmed, including 13 deaths, and 12 Rift Valley fever virus strains were isolated. Moudjeria and Temchecket Departments were the most affected areas
Emerg Infect Dis
No full textHistorically low levels of seasonal influenza circulation were reported during the first years of the COVID-19 pandemic and were mainly attributed to implementation of nonpharmaceutical interventions. In tropical regions, influenza's seasonality differs largely, and data on this topic are scarce. We analyzed data from Senegal's sentinel syndromic surveillance network before and after the start of the COVID-19 pandemic to assess changes in influenza circulation. We found that influenza shows year-round circulation in Senegal and has 2 distinct epidemic peaks: during January-March and during the rainy season in August-October. During 2021-2022, the expected January-March influenza peak completely disappeared, corresponding to periods of active SARS-CoV-2 circulation. We noted an unexpected influenza epidemic peak during May-July 2022. The observed reciprocal circulation of SARS-CoV-2 and influenza suggests that factors such as viral interference might be at play and should be further investigated in tropical settings
Multicultural Validation of the Zuckerman–Kuhlman–Aluja Personality Questionnaire Shortened Form (ZKA-PQ/SF) Across 18 Countries
No full textpeer reviewedThe aim of this study was to assess the psychometric properties of the Zuckerman–Kuhlman–Aluja Personality Questionnaire shortened form (ZKA-PQ/SF) in 18 cultures and 13 languages of different African, American, Asian, and European cultures and languages. The results showed that the five-factor structure with 20 facets replicated well across cultures with a total congruence coefficient of .97. A confirmatory factor analysis (CFA) resulted in adequate fit indices for the five factors based on the comparative fit index (CFI), Tucker–Lewis index (TLI; >.90), and RMSEA (.031-.081). A series of CFA to assess measurement invariance across cultures resulted in adequate CFIs and TLIs for configural and metric invariance. However, factors did not show scalar invariance. Alpha internal consistencies of five factors ranged between .77 (Sensation Seeking) and .86 (Neuroticism). The average alpha of the 20 facets was .64 with a range from .43 (SS4) to .75 (AG1). Nevertheless, alpha reliabilities were lower in some facets and cultures, especially for Senegal and Togo. The average percentage of the variance explained based on the adjusted R2 was 2.9\%, 1.7\%, and 5.1 for age, sex, and, cultures, respectively. Finally, multidimensional scaling suggested that geographically or culturally close cultures share mean profile similarities
Multicultural Validation of the Zuckerman-Kuhlman-Aluja Personality Questionnaire Shortened Form (ZKA-PQ/SF) Across 18 Countries
No full textThe aim of this study was to assess the psychometric properties of the Zuckerman–Kuhlman–Aluja Personality Questionnaire shortened form (ZKA-PQ/SF) in 18 cultures and 13 languages of different African, American, Asian, and European cultures and languages. The results showed that the five-factor structure with 20 facets replicated well across cultures with a total congruence coefficient of .97. A confirmatory factor analysis (CFA) resulted in adequate fit indices for the five factors based on the comparative fit index (CFI), Tucker–Lewis index (TLI; \u3e.90), and RMSEA (.031-.081). A series of CFA to assess measurement invariance across cultures resulted in adequate CFIs and TLIs for configural and metric invariance. However, factors did not show scalar invariance. Alpha internal consistencies of five factors ranged between .77 (Sensation Seeking) and .86 (Neuroticism). The average alpha of the 20 facets was .64 with a range from .43 (SS4) to .75 (AG1). Nevertheless, alpha reliabilities were lower in some facets and cultures, especially for Senegal and Togo. The average percentage of the variance explained based on the adjusted R2 was 2.9%, 1.7%, and 5.1% for age, sex, and, cultures, respectively. Finally, multidimensional scaling suggested that geographically or culturally close cultures share mean profile similarities
Power Flow and Stability Control Using an Integrated HV Bundle-Controlled Line-Impedance Modulator
No full textSéroprévalence de la co-infection VIH /virus de l’hépatite B à l’Hôpital de l’Amitié sino-guinéenne (HASIGUI) Kipé/Conakry (Guinée)
No full textObjectif: L’objectif de cette étude était de déterminer la séroprévalence de la co-infection Virus de l’immunodéficience humaine et Virus de l’hépatite B (VIH/VHB) et les facteurs associés chez les patients reçus au laboratoire biomédical de l’Hôpital de l’Amitié Sino-guinéenne (HASIGUI).Méthodologie et Résultats: Il s’agit d’une étude prospective qui a été menée du 18 juillet 2016 au 18 Avril 2017 sur 525 patients reçus au laboratoire biomédical de HASIGUI pour des examens biologiques. La détection du VIH et le typage ont été faits par immuno-chromatographie à l’aide des Kits spécifiques. La recherche de l’hépatite B a été réalisée par la détection de l’AgHBs par immuno-chromatographie à l’aide de kits spécifiques et par méthode ELISA. Les résultats obtenus ont montré que la prévalence de la coinfection VIH/VHB était de 2,3%. L’âge moyen des patients était de 37 ans avec des extrêmes de 1 et 83 ans. Le sexe masculin était le plus représenté (71,2%) avec une sex-ratio (H/F) égal 2,47. La tranche d’âge la plus représentée était celle des 25 à 34 ans (37,7%). Les prévalences du VIH et de l’hépatite B étaient respectivement de 10,5 et 17,9%. La prévalence du VIH était plus élevée chez le sexe féminins (P=0,05). Tous les cas de VIH détectés étaient du type 1 (VIH1).Conclusion et application: Il ressort de cette étude que la séroprévalence du VIH et du virus de l’hépatite B sont élevées à Conakry. En revanche, celle de la co-infection VIH/VHB est relativement faible par rapport à la plupart des données rapportées dans d’autres pays d’Afrique Sub-saharienne. Cependant, la coinfection VIH/VHB pourrait être considérée comme un problème de santé publique non négligeable en Guinée, nécessitant ainsi son diagnostic précoce en organisant des campagnes de sensibilisation et de dépistage dans la population, permettant ainsi une meilleure prise en charge des patients co-infectés (VIH/VHB) par un double traitement antirétrovirales et anti-hépatites B.Mots clés: Co-infection, VIH, AgHBs (VHB), HASIGUI, Kipé/ConakryEnglish Title: Seroprevalence of Hepatitis B Virus and Human Immunodeficiency Virus Coinfection at the Chinese and Guinean Friendships Hospital (HASIGUI) of Kipé Conakry/ GuineaEnglish AbstractObjective: The aim of this study was to determine the seroprevalence of Hepatitis B virus (HBV) and Human Immunodeficiency virus (HIV) coinfection at the Chinese and Guinean friendships hospital of Kipé/Conakry.Methodology and Results: This prospective study was carried out on 525 patients attending to the biomedical laboratory of Kipé/Conakry (HASIGUI) from July 18th, 2016 to April 18th, 2017. HIV and HBV detection assays were done in the sera of all patients by immunochromatographic methods and ELISA. HIV detection and serotyping were processed in sera by immunochromatographic methods. Hepatitis B virus surface Antigen (HBsAg) was detected by immune-chromatographic methods and confirmed by ELISA. The seroprevalence of HIV/HBV coinfection was 2.3%. The mean age was 37 years, ranging from 1 to 83 years. Males were more represented than females and the sex-ratio (M/F) was 2.47%. HIV seroprevalence was 10,5%, while HBV seroprevalence was 17,9%. The HIV prevalence was high in females than males (P=0.05). HIV1 was the only type screened.Conclusion and application of results: This study findings showed that the seroprevalence of HIV/HBV coinfection rate was lower than that reported in other sub-Saharan Africa countries. HBV and HIV infections were similar to some reported prevalence in other sub-Saharan African countries. Then HIV/HBV coinfection must be considered as an important health problems in Guinea. Then, early diagnosis of HIV/HBV co-infected patients must be done to reduce its evolution and to improve its management practices by organizing awarenes and screening campaigns and treatment for both infections, using molecules against HBV and HIV infections.Keywords: HIV, HBV/HBsAg, Co-infection; HASIGUI; Kipé/Conakr
Analysis of a Dengue Virus Outbreak in Rosso, Senegal 2021
No full textSenegal is hyperendemic for dengue. Since 2017, outbreaks have been noticed annually in many regions around the country, marked by the co-circulation of DENV1-3. On 8 October 2021, a Dengue virus outbreak in the Rosso health post (sentinel site of the syndromic surveillance network) located in the north of the country was notified to the WHO Collaborating Center for arboviruses and hemorrhagic fever viruses at Institut Pasteur de Dakar. A multidisciplinary team was then sent for epidemiological and virologic investigations. This study describes the results from investigations during an outbreak in Senegal using a rapid diagnostic test (RDT) for the combined detection of dengue virus non-structural protein 1 (NS1) and IgM/IgG. For confirmation, samples were also tested by real-time RT-PCR and IgM ELISA at the reference lab in Dakar. qRT-PCR positive samples were subjected to whole genome sequencing using nanopore technology. Virologic analysis scored 102 positives cases (RT-PCR, NS1 antigen detection and/or IgM) out of 173 enrolled patients; interestingly, virus serotyping showed that the outbreak was caused by the DENV-1, a serotype different from DENV-2 involved during the outbreak in Rosso three years earlier, indicating a serotype replacement. Nearly all field-tested NS1 positives samples were confirmed by qRT-PCR with a concordance of 92.3%. Whole genome sequencing and phylogenetic analysis of strains suggested a re-introduction in Rosso of a DENV-1 strain different to the one responsible for the outbreak in the Louga area five years before. Findings call for improved dengue virus surveillance in Senegal, with a wide deployment of DENV antigenic tests, which allow easy on-site diagnosis of suspected cases and early detection of outbreaks. This work highlights the need for continuous monitoring of circulating serotypes which is crucial for a better understanding of viral epidemiology around the country
Emerg Infect Dis
No full textThe spread of severe acute respiratory syndrome coronavirus 2 began later in Africa than in Asia and Europe. Senegal confirmed its first case of coronavirus disease on March 2, 2020. By March 4, a total of 4 cases had been confirmed, all in patients who traveled from Europe
