10,695,855 research outputs found
The role of 3 Tesla diffusion-weighted imaging in the differential diagnosis of benign versus malignant cervical lymph nodes in patients with head and neck squamous cell carcinoma.
he aim of this study was to validate the role of diffusion-weighted imaging (DWI) at 3 Tesla in the differential diagnosis between benign and malignant laterocervical lymph nodes in patients with head and neck squamous cell carcinoma (HNSCC). Materials and Methods. Before undergoing surgery, 80 patients, with biopsy proven HNSCC, underwent a magnetic resonance exam. Sensitivity (Se) and specificity (Spe) of conventional criteria and DWI in detecting laterocervical lymph node metastases were calculated. Histological results from neck dissection were used as standard of reference. Results. In the 239 histologically proven metastatic lymphadenopathies, the mean apparent diffusion coefficient (ADC) value was 0.903 x 10-3 mm2/sec. In the 412 pathologically confirmed benign lymph nodes, an average ADC value of 1.650 x 10"3 mm2/sec was found. For differentiating between benign versus metastatic lymph nodes, DWI showed Se of 97% and Spe of 93%, whereas morphological criteria displayed Se of 61% and Spe of 98%. DWI showed an area under the ROC curve (AUC) of 0.964, while morphological criteria displayed an AUC of 0.715. Conclusions. In a DWI negative neck for malignant lymph nodes, the planned dissection could be converted to a wait-and-scan policy, whereas DWI positive neck would support the decision to perform a neck dissection
Collaborative Learning through Flexible Web CVE: The Experience of WebTalk
This chapter describes the technological platform of the authors’ learning experiences and its evolution through the years, providing insights into the reasons that led to significant design choices and offering guidelines on how to deal with technological issues
La grappa: aspetti di miglioramento per l'esaltazione del carattere
Si presentano i risultati di una procedura innovativa e brevettata di gestione delle flemme che, nel rispetto della tradizione, porta all’ottenimento di grappe più fini, meno ricche di componenti stucchevoli da “frutta matura” e comunque ancora ben caratterizzate dal punto di vista terpenico. Tali grappe appaiono anche particolarmente adatte all’invecchiamento
Die Familien v. Hartmann und v. Barchetti Eigentümer des Hauses Wels, Pfarrgasse 15, im 19. Jahrhundert
Supply Chain Management meets Auto-ID Management: A Structured Approach
Nowadays, firms need to support e-business through solutions that guarantee, on the one hand, the supply chain management (SCM) and, on the other, products’ identification and traceability (ID automation). These two
aspects have been faced, up until now, in a separate manner and adhered to the definition of established standards. Thus, we propose an approach that allows the integration of SCM and ID-automation software architectures and, at the same time, guarantees the separation of concerns. In this paper, we also present an implementation that uses two systems: the data interchange system based on the ebXML standard and the traceability system based on the EPCglobal standard. According to this approach, we propose a preliminary implementation experience for the pharmaceutical sector
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