593 research outputs found
Interview with Azar Nafisi
Iranian author Azar Nafisi speaks about her experiences and the themes of women's rights and struggle that motivate her work including her famous memior Reading Lolita in Tehran. She also shares her thoughts and feelings on the 40 year fight for women's rights in Iran
Comment on: The protective role of silymarin and deferoxamine against iron dextran-induced renal iron deposition in male rats
Azar Nafisi, 39th Annual ODU Literary Festival
Azar Nafisi is the author of numerous books including Reading Lolita in Tehran: A Memoir in Books, which has been translated in 32 languages; Anti-Terra: A Critical Study of Vladimir Nabokov’s Novels; and The Republic of Imagination: America in Three Books. Her work has been published in The New York Times, The Washington Post, and New Republic. She has received many literary and humanitarian awards including the Prix du Meilleur Livre Étranger; an American Immigration Law Foundation achievement award; a Persian Golden Lioness Award for Literature from the World Academy of Arts, Literature, and Media; and a Cristóbal Gabarrón Foundation International Thought and Humanities Award. She currently is a visiting fellow at the Foreign Policy Institute of Johns Hopkins University in Washington, DC
Correlation of Serum Magnesium with Serum Parathormone Levels in Patients on Regular Hemodialysis
Secondary hyperparathyroidism (SHPT) is a common, important, and treatable complication of end-stage renal disease. This study was conducted to investigate the role of serum magnesium (Mg) in regulating the secretion of parathyroid hormone (PTH) by the parathyroid gland in patients on maintenance hemodialysis (HD). Pre-dialysis serum levels of calcium (Ca), phosphorus (P), Mg, alkaline phosphatase (ALP), intact serum PTH (iPTH), serum 25-hydroxy Vitamin D (25-OH Vit D) and plasma bicarbonate (HCO3) were measured. The Urea Reduction Rate as well as duration and dosage of HD treatment were noted. Our study did not show any significant correlation between serum Mg levels and duration of HD treatment, levels of serum ALP, and plasma HCO3, Ca and P. An inverse correlation, albeit insignificant, was found between the serum Mg levels and iPTH (r=-0.30 p=0.079); also, a significant positive correlation was found between serum Mg levels and serum 25-OH Vit D levels (r= 0.40 p= 0.009). Our findings are in agreement with previous data, which suggest that factors other than serum Mg are more important in the regulation of PTH secretion in HD patients. A positive and strong association between serum Mg with 25-OH Vit D needs to be studied in greater detail
Correlation of serum parathyroid hormone with pulmonary artery pressure in non-diabetic regular hemodialysis patients
Abstract
Introduction: Pulmonary artery hypertension in end-stage renal disease is associated by significantly increased
morbidity and mortality. Serum parathormone may increase among patients on hemodialysis and influence various
organs.
Objectives: This study sought to find the association of serum parathormone level and pulmonary artery pressure in a
group of non-diabetic patients on regular hemodialysis.
Materials and Methods: This prospective investigation was conducted in the hemodialysis section of Shahrekord
University of Medical Sciences in 2013. Doppler echocardiography were used to assess pulmonary artery pressure.
Pulmonary arterial hypertension is defined as systolic PAP≥35 mm Hg at rest. Serum parathormone was measured by
ECL method.
Results: Sixty-five, non-diabetic hemodialysis patients were studied. Mean (±SD) of age of the patients was 56.35±20.41
years. Mean (±SD) of iPTH was 251.55±97.27 pg/ml. In this study, a significant positive association of serum iPTH with
pulmonary artery pressure in patients was seen (r=0.27, p=0.029).
Conclusion: In the present study, we detected a significant positive association of serum parathyroid hormone with
pulmonary artery pressure of hemodialysis patients however, our observations, warranting further investigations to
evaluate the clinical aspect of the association of serum PTH with pulmonary artery pressure.
Keywords: End-stage renal disease, Hemodialysis, Pulmonary hypertension, Parathormone
Please cite this paper as: Heidari M, Mardani S, Baradaran A. Correlation of serum parathyroid hormone with
pulmonary artery pressure in non-diabetic regular hemodialysis patients. J Parathyr Dis 2014; 2(2): 78-80.
Copyright © 2014 The Author(s); Published by Nickan Research Institute. This is an open-access article distributed
under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which
permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Association of Helicobacter pylori IgG antibody with various demographic and biochemical parameters in kidney transplant recipients
Few reports are available regarding the promoting factors that affect Helicobacter pylori (H. pylori) infection in renal transplant (RTx) patients. We report a cross-sectional study that was conducted on a group of stable RTx patients to investigate the relationship of various demographic and biochemical parameters of these patients with serum H. pylori IgG antibody titer as a sign of H. pylori infection. A total of 72 patients who were referred to the clinic for continuing their treatment were enrolled in this study. These patients included 47 males and 25 females. The mean age of the study patients was 44 (±12) years. The mean length of time after they received a transplanted kidney was 67.5 (±42) months (median: 62 months). The mean value of serum H. pylori-specific IgG antibody titer among these patients was 3 (±4.6) U/mL (median: 1 U/mL), and that of intact parathormone (iPTH) was 18.4 (±8.2) pg/mL (median: 16.5 pg/mL). The mean serum magnesium (Mg) was 1.9 (±0.20) mg/dL (median: 1.9 mg/dL) and the mean creatinine clearance was 53 (±11) mL/min (median: 56 mL/min). In this study population, there was no significant difference in the H. pylori IgG antibody titers, serum iPTH, Mg, calcium, alkaline phosphatase and albumin levels as well as body mass index (BMI) between males and females or diabetics and non-diabetics. There was no significant relationship between serum H. pylori IgG antibody titers and the age of the patients, BMI, serum Alb, phosphorus, Ca, serum leptin and serum ALP. Significant negative correlation between serum H. pylori IgG antibody titers and serum Mg (r = -0.30, P = 0.01) and serum iPTH (r = -0.25, P = 0.03) was seen. A significant positive correlation was found between serum H. pylori IgG antibody titer and creatinine clearance (r = 0.26, P = 0.02), and a near-significant positive correlation was found with the duration of RTx (r = 0.20, P = 0.08). Our study shows that the correlation of H. pylori IgG antibody titer with some demographic and biochemical indices in RTx recipients may be different from what has been reported in hemodialysis patients. Larger clinical studies are needed to assess the clinical implications of our findings
Inlet patch: The under-explored island
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Helicobacter pylori infection and serum homocysteine in hemodialysis patient
Hyperhomocysteinemia is a factor that is found to be responsible for the development of atherosclerosis in the setting of chronic Helicobacter pylori (H. Pylori) infection. In the recent years, homocysteine (Hcy) has been demonstrated to be an important contributor to atherosclerosis. This study was undertaken to elucidate whether in patients with uremia on maintenance hemodialysis (HD), the infection of H. pylori affects the levels of Hcy. he patients were 39 HD ones with mean ages of 46 +/- 18 years. The time of hemodialysis were 30 +/- (35) months (median: 18 months). The value of serum Hcy of all patients was 5 (+/- 2) mu mol/L (median: 4.5 mu mol/L). The value of serum H. Pylori specific IgG antibody titers was 7.6 (+/- 9.9) u/ml (median: 2 u/ml). In this study a positive correlation was found between serum homocysteine and H. Pylori infection. As elevation of serum Hcy is observed in the great majority (>85%) of patients undergoing maintenance dialysis, further research is needed to determine the importance of association between elevated serum homocysteine and H. Pylori infection. Furthermore, whether or not the treatment of H. pylori infection in HD patients can diminish serum homocysteine level should be elucidated. Mahmoud Rafiean-Kopaei, Azar Baradaran, Ahmad-Reza Maghsoudi, Shamin Ghobadi and Hamid Nasri. Helicobacter pylori infection and serum homocysteine in hemodialysis patient. Life Sci J 2012;9(4):3696-3702]. (ISSN: 1097-8135). http://www.lifesciencesite.com. 54
Comment on: Anti-Oxidative Stress Activity of Stachys lavandulifolia Aqueous Extract in Humans
Re: Protective Role of Silymarin and Deferoxamine against Iron Dextran - Induced Renal Iron Deposition in Male Rats
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