196,306 research outputs found
Implementazione di PostgreSQL-PostGIS per l'analisi di immagine satellitare: test di applicabilità per la atimetria marina
Nell'ambito del progetto PRIN2008 l’unità di ricerca di Cagliari è impegnata nell'individuazione di
metodologie per l'implementazione di una serie di funzioni PostgreSQL-PostGIS per valutazioni
statistiche e analisi delle serie temporali/spaziali, sia con algoritmi di uso generale sia con l'applicazione di modelli specifici. Il server PostgreSQL -PostGIS permette, infatti, l'inserimento di
nuove funzioni, e librerie di funzioni, in aggiunta a quelle di corredo, quali operatori geometrici,
funzioni geometriche, conversioni geometriche, operatori e calcoli matriciali.
Delle nuove funzioni si vuole, in pratica, verificare l'utilità, l'applicabilità e la correttezza in
procedure di interazione su interfaccia WEB-GIS.
Procedure intese a fornire analisi e valutazioni non di precisione ma comunque utili come strumento di approccio e sperimentazione di metodologie di analisi. La validità delle funzioni implementate viene effettuata con l’ausilio di un WEB-GIS che, per quanto non di precisione, aiuta a verificare la correttezza dei modelli applicati e, riguardo alla validazione dei parametri, si tiene conto del livello di confidenza prefissato.
Allo scopo di verificare capacità e rendimento delle funzioni implementate in PostgreSQL-PostGIS è stato “trasferito” sul server uno studio di analisi di immagine satellitare per la determinazione
delle curve batimetriche, precedentemente sviluppato in ambiente IDL-ENVI.
In particolare si è fatto ricorso alle funzioni GDAL PostGIS Raster per l'immissione delle immagini
raster satellitari nel database, previa trasformazione in forma tabellare, così da poter essere in seguito utilizzate sia dalle funzioni originali PostgreSQL/PostGIS che da quelle da noi implementate
Implementazione di server WEB-GIS con funzioni di analisi spazio-temporale
Nell'ambito del progetto PRIN2008 l’unità di
ricerca di Cagliari è stata impegnata nell'individuazione di
metodologie per l'implementazione di una serie di funzioni
PostgreSQL-PostGIS orientate a valutazioni statistiche e
analisi delle serie temporali, sia con algoritmi di uso generale
sia con l'applicazione di modelli specifici. Il server PostgreSQL
-PostGIS permette, infatti, l'inserimento di nuove funzioni, fino
a librerie di funzioni, in aggiunta a quelle di corredo, quali
operatori geometrici, funzioni geometriche, conversioni
geometriche, operatori e calcoli matriciali. È stata inserita la
funzione “batimetria” per la determinazione in bassa
precisione delle curve batimetriche marine prossime alle coste
ottenute da analisi di immagini satellitarie. In questo modo è
stata verificata la buona funzionalità e, quindi, applicabilità,
insieme con la correttezza, di implementazione di nuove
funzioni per DBMS in procedure di interazione con Server
WEB-GIS Open Source
Lipid supplementation in small ruminant nutrition and dairy products quality: implications for human nutrition
Subsurface profiling along Banni Plains and bounding faults, Kachchh, Western India using microtremors method
The present article is a maiden attempt to map shallow subsurface rheological interfaces laterally across the Banni Plains and to decode geometry of the antecedent faults associated with the Kachchh Mainland Fault using the microtremor method. We conducted microtremor data acquisition for thirty-one sites along N-S transect from Loriya in Mainland Kachchh to Bhirandiara towards Patcham Island. Results from H/V spectral ratio technique show presence of two distinct rheological interfaces characterised by the resonant frequency (f(r)) ranges 0.23-0.27 Hz and 0.8252-1.5931 Hz respectively. The above frequency ranges are correlated with the depths of the Mesozoic-Basement (M-B) interface and the Quaternary-Tertiary (Q-T) interface. Using either the velocity (Vs) of seismic waves at the M-B and Q-T interfaces (calculated as 1830 m/s and 411 m/s respectively) or the standard non-linear regression relationship derived for the Banni Plains (h = 110.18f(r)(-1.97)) we estimate the depth range for M-B interface to be 1442-1965 m and for Q-T interface to be 44-160 in. The subsurface profile across the Banni Plains educe cluster of four faults that develop an array of imbricate faults at the forefront of the Kachchh Mainland Fault within the Banni Footwall Syncline. The geometry of the faults suggests a `positive flower structure' indicating step-overs and strain restraining bends displaying push-ups resulting from localized shortening between converging bends of Kachchh Mainland Fault and the South Wagad Fault. The Banni Footwall Syncline preserves evidence of two episodes of deformations. The initial deformation event led to subsidence within the Kachchh Mainland Fault Zone bringing Mesozoic sequence juxtaposed to the basement rocks, whereas the later event is dominated by an uplift developing a positive flower structure in the Kachchh Mainland Fault Zone. Finally, the present study provides a mechanism to investigate faults and fault geometries correlating surface structural grains with subsurface structures
Analysis of Livelihood Structure of Pastoralists in Banni Grassland in Kachchh District of Gujarat in India
Banni grassland in Kachchh district of Gujarat in India is situated at 69024’ E longitude to 23042’ N latitude axis and spread in about 3847 sq km area. Banni region is a vast salt affected plain and experiences arid climate with average rainfall of 317mm received by southwest monsoon spread between June to September with high coefficient of Variation of 65%. Banni grassland is home to migratory pastoralists, generally called maldharies, for more than 500 years. Banni area comprises of 48 hamlets/villages organized into 19 Panchayats with a population of approximately 40,000 people. Maldharies are landless and depend upon village commons (Gauchars) for their livestock rearing. Banni buffaloes, kankrej cows, sheep, goat and camel are the domesticated animals. Breeding of kankrej bullocks and banni buffaloes for draught and milch purpose respectively was the traditional occupation and main source of income for maldharies. They breed and sell these animals to farmers in Gujarat and other parts of the country. Since late 1970s there has been a gradual shift in livestock population formerly dominated by kankrej cows to one now dominated by banni buffaloes. Change in vegetation pattern, especially invasion of Prosopis juliflora is attributed as one of the main reasons by farmers for this occupational shift. Feeding on P. juliflora pods over a period of time leads to dislocation and weakening of jaws in cows leading to their death. Mechanization of agriculture in Kachchh and other parts of Gujarat has led to reduction in use of bullocks for draught purpose. Consequently the demand for kankrej bullocks has also reduced drastically. On the other hand, banni buffaloes are tolerant to ill effects of feeding on P. juliflora. Hence, number of banni buffaloes has increased drastically since 1980s when compared to kankrej cows. Improved road connectivity of villages in banni area to Bhuj city and other towns and establishment of milk collection centers in the region has also played a vital role in growth and development of banni buffalo based dairy enterprise. These internal and external factors have led to change in occupational structure in banni region. Hence, documentation of changes in occupational structure and the driving factors behind such change is important. This research paper has the objective of analyzing the combination of various livelihood options available for pastoralist households of banni region
Dietary therapeutic strategy for the treatment of neurodegenerative disorders
Dietary therapeutic strategy for the treatment of neurodegenerative disorders
Anna Petroni1
, Marco Cappa2
, Carla Bizzarri2
, and Sebastiano Banni3
1
[email protected], Department of Pharmacological Sciences, via Balzaretti 9, Milan,Italy;
[email protected], [email protected], Department of Pediatric Medicine, Endocrinology Unit,
Children’s Hospital “Bambino Gesù”, Rome, Italy; 3 [email protected], Department of Experimental Biology,
University of Cagliari, Italy.
Neurodegenerative disorders can have different etiopathogenesis but they do share metabolic pathways and
similar clinical manifestations. In Alzheimer’s disease, leukodystrophies and other disorders, characterized
in particular by the chronicity, the occurence of lipid metabolic alteration and secondary inflammatory events
can contribute to the progression of the disorders.
Lipid and steroid hormone pathways are altered, as an example, in X-linked Adrenoleukodystrophy (X-ALD),
a demyelinating disorder. Lorenzo's Oil (LO), a mixture of glyceryl trioleate and glyceryl trierucate (erucic
acid), is able to normalize lipid metabolic alterations in X-ALD patients although not always the progression
of the disease. Our objective was to introduce conjugated linoleic acid isomers (CLA) as therapeutic
approach for X-ALD and for other neurodegenerative disorders.
We tested a mixture of LO (40 g/day) with CLA (5 g/day) for 2 months, in female heterozygous X−ALD
individuals, to determine whether CLA crosses the blood-brain barrier and exerts a synergistic effect with LO.
Since secondary inflammatory processes are present in this pathology we evaluated Somatosensory evoked
potentials (SEPs), interleukins, and other standard biochemical and clinical parameters.
After the treatment, CLA was detected in the liquor (not erucic acid) indicating the passage through the
blood-brain barrier and the mixture decreased abnormal lipid plasma levels. SEPs were improved after the
treatment with the mixture, whereas with dietary LO, were found unchanged (Restuccia D et al., 1999).
Inflammation is known to be a crucial factor for ALD pathogenesis and other disorders. This concerted
action results in an improvement of the SEPs. A better SEP is a sign of neurological improvement which
implies an ongoing physiological recovery.
Our results are opening the field for a novel promising therapeutic strategy for X-ALD and other
neurodegenerative disorders.
Sponsor: Biomedicine and Nutrition Association, Italy (www.biomedicinanutrizione.org)
Esempio di Implementazione di PostgreSQL-PostGIS per l'analisi di immagine satellitare tramite WEB-GIS
Banni grassland, a geoheritage landscape of Western India: Endless possibilities for Geo-Eco-Socio tourism
Awareness of geoheritage, geoconservation, and geotourism research has significantly increased globally during the past two decades. A peri-cratonic Kachchh rift basin in western India exposes varied geological formations and structures, from the Jurassic to Recent. Kachchh basin is characterized by rocky uplifts and pediments with deciduous and scanty forest, which suggest a semi-arid climate while hypersaline Rann and Banni plains show an arid to hyper-arid climate. The deteriorating grasslands of Banni were known as Savanna-type grasslands of Asia. Several natural and anthropogenic factors have led to its depletion. Owing to its unique geological, aesthetic, botanical and cultural values, the Banni Grasslands hold a potential candidature for a critical geo-observatory site status, both at national and international levels. The geological evolutionary history of this fragile eco-zone with a strong anthropological background calls for a holistic sustainable development that encompasses the socio-economical needs and ecological agility at the same time. The plains of Banni are unique geomorphic features with distinct ecology, traditional climate-human sustainable practice model and diverse folk arts and skills of making climate-tectonic resistive dwellings. The grasslands to the north merge into the marshes and uplifted mudflats as the Rann terrain. The present paper is an attempt to understand the socio-economic intricacies of Banni grassland in light of its unique geological origin and ecological vulnerabilities. It focuses on traditional and sustainable ecological knowledge of the local folks with distinct harmony of their art and architecture so interwoven with the activeness of the climate and tectonics of Banni. The inter-sectorial conflicting interests have redefined the fate of this terrain, in recent decades. It presents the status quo of its geological, anthropological and ecological facets and establishes the way forward that sustains the social, economic and above all ecological obligations in the long run
From nutritional bioactive compounds to the development of therapies for neurodegenerative disorders
Common metabolic alterations are associated with the progression of a growing number of neurodegenerative disorders, characterized by different ethiopatogenesis. In the case of adrenoleukodystrophy (X-ALD), an inherited demyelinating disorder, the mutated protein (ALDP) impair lipid catabolism. During the progression of this pathology, ALDP-related proteins can be overexpressed and partially compensate the lipid metabolic impairment.
Other secondary alterations develop during the progression of the disorder such as oxidative stress, inflammatory cascade, peroxisomal impairment amplify neurodegenerative conditions. The therapeutic control of these secondary events are fundamental.
A crucial factor for the treatment of X-ALD and neurodegenerative conditions is the passage of drugs through the blood-brain barrier. The aim of our research was to develop a therapeutic strategy utilizing nutritional bioactive compounds. We have demonstrated that specific compounds, utilized in the dietary therapy for X-ALD, can pass through blood-brain-barrier and they are detected in the liquor of treated patients (Cappa et al., J Inherit Metab Dis, 35:899-907, 2012). We investigated the molecular mechanisms of specific bioactive compounds to develop a dietary strategy aimed to modulate the progression of neurodegenerative disorders
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