42,935 research outputs found
Association of recreational physical activity with homocysteine, folate and lipid markers in young women
No full textEur J Appl Physiol. 2009 Jan;105(1):111-8. Epub 2008 Oct 14.
Association of recreational physical activity with homocysteine, folate and lipid markers in young women.
Di Santolo M, Banfi G, Stel G, Cauci S.
SourceDepartment of Biomedical Sciences and Technologies, School of Medicine, University of Udine, 33100, Udine, Italy.
Abstract
We assessed the influence of recreational physical activity in young healthy women on homocysteine, a potential risk factor for cardiovascular disease (CVD). Participants were 124 23-year-old normal-weight Italian recreational athletes (performing 8.7 +/- 2.46 h week(-1) exercise) and 116 controls. Median blood homocysteine, folate and lipid markers did not differ between athletes and controls. Elevated homocysteine levels at CVD risk > or =12.0 and > or =15.0 micromol l(-1) were not different between groups. Continuous homocysteine was inversely related to folate (P or =15.0 micromol l(-1). Recreational physical exercise does not adversely impact homocysteine levels among young women. Only low folate significantly increases the risk for hyperhomocysteinemia in young women
Relation between values of haemoglobin, erythrocytes and reticulocytes and body mass index in elite athletes of different sports disciplines
No full textRelation between body mass index and serum aminotransferases concentrations in professional athletes
No full textReference intervals commonly used for evaluating and interpreting laboratory values obtained in athletes are the same used in the general population. Aminotransferases (aspartate aminotransferase [AST], and alanine aminotransferase [ALT]) are commonly analyzed in serum for evaluating hepatic function. Some studies in the general population and in blood donors testified that ALT concentrations clearly correlated with weight and body mass
Banfi Antonio
No full textInfluenzato da G. Simmel, E. Husserl e P. Martinetti, Antonio Banfi sviluppò, in articolate opere degli anni Venti, una propria proposta sistematica di filosofia critica della cultura. In questo contesto, egli apprezzò il potenziale critico e anticonformista di alcuni atteggiamenti della coeva “teologia dialettica” protestante verso le posizioni date, di tipo culturale, economico o politico. Nei decenni successivi, la sua attenzione si spostò verso una critica sociale ispirata al marxismo. Pur mantenendo rispetto per chi teneva «desta la coscienza del trascendente e della problematicità della vita», Banfi concluse che le forze costruttive della modernità risiedevano nella storicità e nell’azione sociale. La sua eredità si riflette nel pensiero di numerosi studiosi italiani del Novecento, contribuendo alla formazione di un approccio interdisciplinare tra filosofia, pedagogia e critica culturale.
Parole chiave: Antonio Banfi, filosofia della cultura, filosofia della religione, ragione critica, dialettica
Influenced by G. Simmel, E. Husserl, and P. Martinetti, Antonio Banfi developed, in elaborate works of the 1920s, his own systematic proposal for a critical philosophy of culture. In this context, he appreciated the critical and unconventional potential of certain attitudes of the contemporary Protestant “dialectical theology” towards established cultural, economic, or political positions. In the following decades, his focus shifted towards a social critique inspired by Marxism. While maintaining respect for those who kept “the consciousness of the transcendent and the problematic nature of life” alive, Banfi concluded that the constructive forces of modernity resided in historicity and social action. His legacy influenced many 20th-century Italian scholars, fostering an interdisciplinary approach to philosophy, pedagogy, and cultural criticism.
Keywords: Antonio Banfi, Philosophy of Culture, Philosophy of Religion, Critical Reason, Dialectic
Could platelet rich plasma have effects on systemic circulating growth factors and cytokine release in orthopaedic applications?
No full textThe use of platelet rich plasma (PRP) has been proposed for tendon and ligament healing, because platelets release growth factors and cytokine/chemokines which aid the regeneration of the tissues. We applied PRP in tendinopathies of professional athletes and we measured, from the time of PRP application until 24 hours later, a series of cytokines and growth factors in serum obtained from peripheral blood in five male subjects for studying possible systemic effect of the therapy. We did not observe modifications of these parameters: interleukin 4, interleukin 6, interleukin 10, interleukin 1a, interleukin 1b, tumor necrosis factor a (TNFa) and interferon g. We observed modifications of vascular endothelial growth factor (VEGF), endothelial growth factor (EGF), and chemokine (C-C motif) ligand 2 (CCL2)
Rituximab monotherapy for remission induction of proliferative lupus nephritis flares: description of 3 cases
No full textBackground: The efficacy and safety of rituximab when not associated with other immunosuppressive therapy in induction of remission of proliferative lupus nephritis (PLN) has not until now been proven.
Methods: We report on 3 patients with PLN (class IV), 1 with a nephritic flare and 2 with a proteinuric flare (all with nephrotic syndrome (NS)) treated with 3 intravenous methylprednisolone pulses for 3 consecutive days and with rituximab at day 3 and day 18 associated with oral prednisone. At the beginning of the fourth month of therapy, mycophenolate mofetil was combined with prednisone.
Results: Three months after the beginning of therapy, renal function improved in the patient with the nephritic flare, and proteinuria fell to within the non-nephrotic range in all 3 patients. At the end of a follow-up of 24 months, the patient with the nephritic flare had normal renal function (serum creatinine from 1.7 to 1 mg/dL) and mild proteinuria (from 6 to 0.7 g/24 hours). The second patient was in complete remission (proteinuria from 5 to 0.127 g/24 hours) 27 months after the beginning of therapy. In the last patient, followed for 10 months, mild proteinuria persisted (from 6.6 to 0.7 g/24 hours). The therapy was well tolerated by all patients. No adverse effects occurred during the follow-up.
Conclusion: Although our results must be confirmed by larger prospective studies, rituximab associated with methylprednisolone pulses without any other concomitant immunosuppressive drug seems to be effective and safe for induction therapy of severe flares of PLN
Long-term outcome of renal transplantation in patients with idiopathic membranous glomerulonephritis (MN)
No full textMethods. The outcomes of 35 first renal transplants performed between 1975 and 2008 in patients with MN were compared with those of 70 controls transplanted in the same period and matched for sex, age and source of donors.
Results. The mean post-transplant follow-up was 117 +/- 86 months for MN patients and 123 +/- 83 months for controls. At 15 years, patient survival was 96% in patients with MN and 88% in the controls (P = ns), while graft survival rates were respectively 40% and 69% (P = 0.06). MN recurred in 12 patients (34%), namely in 4/8 (50%) patients who received the kidney from related living donors and in 8/27 (29.6%) who received the kidney from a deceased donor. Recurrence led to graft failure in six patients, all deceased donor kidney recipients, within 54 +/- 33 months. The other six grafts are functioning 134 +/- 73 months after transplantation. Patients with recurrence were more frequently females (42% vs 4.3%, P = 0.02). The recurrence occurred earlier (4.8 +/- 3.0 vs 45.6 +/- 46.9 months, P = 0.05), and there was a trend to develop a higher proteinuria (7.1 +/- 5.5 vs 3.67 +/- 2.6 g/24 h, P = 0.1) in grafts eventually lost because of recurrence.
Conclusions. The long-term patient survival was similar in renal transplant recipients with MN and in controls. The graft survival was lower in MN patients than in controls, although the difference was at borderline significance. Recurrence occurred in one-third of the patients and caused graft loss in half of them
Effects of cold-water immersion of legs after training session on serum creatine kinase concentrations in rugby players
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