1,721,581 research outputs found

    Branch Retinal Vein Occlusion: Classification and Treatment

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    Branch retinal vein occlusion (BRVO) refers to a heterogeneous group of disorders with different clinical aspects, courses, and probably therapy. Depending on the site of the arteriovenous crossing, we can roughly divide BRVO into 3 main groups: major BRVO, hemispheric retinal vein occlusion, and macular BRVO. Main treatment options include laser treatment, corticosteroid administration, anti-VEGF drugs, and sheathotomy with or without vitrectomy. Laser photocoagulation, as demonstrated by the Branch Vein Occlusion Study, represents the gold standard for the treatment of macular edema and ocular neovascularization following BRVO. The limited functional outcomes achievable by means of laser treatment have prompted researchers to try alternative options, with varying results. The recent introduction of combined therapies for macular edema may provide a superior approach in an attempt to improve and stabilize visual acuity over a long-term follow-up. Copyright (C) 2009 S. Karger AG, Base

    Juxtafoveal Choroidal Neovascularization Secondary to Persistent Placoid Maculopathy Treated with Intravitreal Bevacizumab

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    Purpose: To describe a case of persistent placoid maculopathy (PPM) associated with juxtafoveal choroidal neovascularization (CNV) treated with intravitreal bevacizumab injection (IVBI). Design: Interventional case report. Methods: A 60-year-old patient referred for sudden vision loss was diagnosed with PPM complicated by a disciform scar in the right eye and juxtafoveal CNV in the left eye, undergoing 2 IVBIs. Results: Best-corrected visual acuity passed from 20/32 to 20/20 after 2 IVBIs, with complete resolution of intraretinal and subretinal fluid and disappearance of fluorescein leakage. Conclusions: IVBI is a promising treatment option for juxtafoveal CNV secondary to PPM

    Treatment options for diffuse diabetic macular edema

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    PURPOSE. To describe the current management of diffuse diabetic macular edema (DOME). METHODS. Review and discussion of the literature regarding DOME. RESULTS. Diffuse diabetic macular edema is a condition that can be managed by means of several treatment options, including focal/grid laser photocoagulation, intravitreal or periocular corticosteroids, intravitreal anti-vascular endothelial growth factor (VEGF), and vitrectomy with or without internal limiting membrane peeling. CONCLUSIONS. Even though there is no randomized clinical trial specifically designed to assess the best treatment approach for DOME, new therapeutic approaches based on intravitreal injections of corticosteroid and anti-VEGF molecules offer new hope for its management
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