102,693 research outputs found
Che cosa si deve intendere per società cooperative / G. Velio Ballerini
No full textChe cosa si deve intendere per società cooperative / G. Velio Ballerini
Torino : tip. Roux e Favale, 1883
15 p. ; 22 cm
Estr. da: Rivista amministrativa
Accurate and reliable segmentation of the optic disc in digital fundus images
No full textWe describe a complete pipeline for the detection and accurate automatic segmentation of the optic disc in digital fundus images. This procedure provides separation of vascular information and accurate inpainting of vessel-removed images, symmetry-based optic disc localization, and fitting of incrementally complex contour models at increasing resolutions using information related to inpainted images and vessel masks. Validation experiments, performed on a large dataset of images of healthy and pathological eyes, annotated by experts and partially graded with a quality label, demonstrate the good performances of the proposed approach. The method is able to detect the optic disc and trace its contours better than the other systems presented in the literature and tested on the same data. The average error in the obtained contour masks is reasonably close to the interoperator errors and suitable for practical applications. The optic disc segmentation pipeline is currently integrated in a complete software suite for the semiautomatic quantification of retinal vessel properties from fundus camera images (VAMPIRE).Copyright 2014 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited
Neurotrophic factors in the aging brain
No full textBasic research on the nerve growth factor (NGF) has led to the stimulating hypothesis that an important link in the neuronal aging process may be the reduced synthesis, availability and utilization of trophic factors. The hypothesis needs confirmation together with the understanding of the role and properties of the numerous factors which have joined NGF. Development, survival and death of the nerve cells seem to depend on the activity of an unexpectedly large number of trophic factors. However, their interactions and regional distribution, the distribution and specificity of their receptors, need to be investigated. Since some growth factors have already been used in man, such as the hemopoietic growth factors in blood diseases, and epidermal growth factor in intestinal atrophy, it is very likely that long before all basic information is marshalled, trophic factors will be administered to aged patients affected by Alzheimer's and other degenerative diseases. Let us hope that the results will not be disappointing and that a new therapeutic avenue might really have been opened
Autism: Disembodied Existence
No full textThis paper considers the nature of schizophrenic autism and urges its importance for understanding the phenomenological core of schizophrenia.
Different clinical manifestations of schizophrenic autism
are demonstrated, and it is asked whether these might reflect different aspects of one underlying phenomenologically intelligible phenomenon. Four phenomenological hypotheses are put forward: that autism is a function of semantic drifting, emotional drifting, ontological incompleteness, or a particular ethic rejecting common sense. By way of conclusion an integrative hypothesis is considered: that autism is intelligible
in terms of the experience of disembodiment
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