105 research outputs found
Author Correction: COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials
No full textIn the original version of this Perspective, the name of the author Giuseppe Curigliano was incorrectly written as Guiseppe Curigiliano. The affiliations have been corrected in the HTML and PDF versions of the manuscrip
Physical properties of simple and complex sugar systems.
No full textHoney, maple syrup and sugars during refining are examples of a complex solutions of concentrated sugars and other solutes. The physical properties of such systems are required for the design and optimization of processes and for the understanding of the behaviour of the final product. Literature shows limited data and even less rigorous analysis of the physical properties of concentrated sugar solutions. A fundamental thermodynamic approach provides an effective basis for the analysis and prediction of these properties. The main focus of this study was to consolidate physical property data for binary sugar systems, analyse the data using existing models, and propose newer models and equations to predict the physical properties of complex sugar solutions like honey.
In order to approach this, the physical properties density, viscosity, electrical conductivity, refractive index, mutarotation and water activity of binary solutions and sugar mixtures ranging from invert sugar solutions to model honey solutions with acid and salt were measured. Models that have been applied to sugar systems were reviewed. An equation for density based on the apparent densities of sugars in solution was validated. A viscosity equation that was extended from previous work with concentrated milk systems, was found to be very effective over the full concentration range of complex sugar solutions. Effects of viscosity on the electrical conductivity of sugar systems were analysed and a model was proposed for electrical conductivity in sugar systems. Hydration theory based on water activity measurements was applied to binary sugar systems and extended to model honey systems. Mixing theories were applied to the calculation of refractive index of solutions and also used as a tool to confirm the solid mass fraction in solutions.
The effect of mutarotation of sugars in viscous sugar solutions was studied using a new NMR technique that was validated using polarimetric measurements. In this study it was found that the mutarotation of glucose was not affected by the viscosity of the solution.
Past and new data and resulting equations provide a solid basis for future modelling and simulation of crystallization in these systems
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Fish Science Research in China: How does it Compare with Fish Research in India?
No full textFish and aquaculture research in the Peopleâ s Republic of China over the six years 1994-1999 has been mapped using data from six databases â three abstracting services and three citation indexes. The results are compared with fish science research in India. During the six years China has published 2035 papers (roughly 4.5 â 5% of the world output) and India 2454. More than 95% of Chinaâ s papers are journal articles, compared to 82.8% of Indian papers. About 78% of Chinaâ s journal paper output has appeared in 143 domestic journals compared to 70% from India in 113 Indian journals. Less than one-eighth of the journal articles published by Chinese researchers are published in journals indexed in SCI, compared to 30% of journal articles by Indian researchers. Less than a dozen papers from each of these countries have appeared in journals of impact factor greater than 3.0. Fish research institutes and fishery colleges are the major contributors of the Chinese research output in this area. In India academic institutions are the leading contributors (61%), followed by central government institutions (>25%). Qingdao, Wuhan, Beijing and Shanghai are the cities and Shandong, Hubei and Fujian are the provinces contributing a large number of papers. As we do not have addresses of all authors in most of the papers, we are unable to estimate the extent of international collaboration. Although Chinaâ s research output and its citation impact are less than those of India, Chinaâ s fish production and export earnings are far higher than those of India. Probably China is better at bridging the gap between knowhow (research) and do-how (technology and creation of employment and wealth). China is pretty strong in extension
Benefits and Challenges of Firm's Expansion to the European Market
No full textPředkládaná práce se zaměřuje na poskytnutí návodu pro vstup indické společnosti
na evropský trh. Diplomová práce je rozdělena do tří kapitol: První kapitola vysvětluje různé teorie, které je možné využít pro podnikání v jiné zemi, a také uvádí výhody, úskalí a problémy při expanzi podniku do zahraničí. Druhá kapitola popisuje jednotlivé metody a data, která byla použita ve třetí, praktické části práce.
V případové studii společnosti Lodestar 3D, představené ve třetí kapitole, byly
provedeny analýzy SWOT a PEST, jejichž cílem bylo identifikovat výhody a nevýhody, které by pro společnost znamenalo založení dceřiné společnosti v České republice. Výsledky těchto analytických nástrojů jsou doplněny informacemi získanými prostřednictvím polostrukturovaného rozhovoru s ředitelem společnosti Lodestar 3D. Hlavní závěr práce navrhuje společnosti Lodestar 3D jasněformulovanou obchodní strategii odkoupení české společnosti a vytvoření nové dceřiné společnosti mateřské společnosti, která sídlí mimo Indii (převodem licencí a povolení), a řešení všech klíčových problémů pro zahájení podnikání ve střední Evropě. Dodržování uvedených pokynů může společnosti pomoci zahájit podnikání a lépe sloužit evropským zákazníkům.The presented thesis focuses to provide a tutorial for the Indian company to enter the European economy. The diploma thesis is divided into three chapters: Chapter one explains the different theories which are available to use for doing business in another country and also lists the benefits, challenges, and problems for the company during its expansion abroad. Chapter two describes the various methods and data which were used in the third, practical part of the thesis.
In the case study of Lodestar 3D company, presented in the chapter three, the SWOT and PEST analyses were carried out to identify the advantages and disadvantages for the company to set up a subsidiary in the Czech Republic. The findings of these analytical tools are supplemented with the information gathered through the semi-structured interview with the director of Lodestar 3D. The main conclusion of the thesis proposes Lodestar 3D a clear-cut business strategy of buying out a Czech company and making it a new subsidiary of the parent company which is based out in India (by transferring licenses and permits) and addressing all the key challenges for starting the business in Central Europe. Following the specified guidelines can help the company to start the business and serve the European customers in a better way
Air-stable magnetic cobalt-iron (Co7Fe3) bimetallic alloy nanostructures via co-digestive ripening of cobalt and iron colloids
No full text
Author Correction: EGFR and HER2 exon 20 insertions in solid tumours: from biology to treatment (Nature Reviews Clinical Oncology, (2022), 19, 1, (51-69), 10.1038/s41571-021-00558-1)
No full textNovel Simulator for Wireline Mini-Fracture Testing
No full textWireline Mini-Fracture testing jobs consist of a short duration, small volume fracturing operation inside an open-hole borehole, where a certain amount of fluid is injected into the formation at constant rate using a Wireline Modular conveyed tool as a source of hydraulic power to pressurize the wellbore. The tool is configured with an inflatable straddle packer and an internal pump, which inflate/deflates the packers and supplies pressure to the formation until a hydraulic fracture is induced. This procedure is used to determine in–situ formation breakdown and closure pressure also known as minimum horizontal closure pressure. This provides vital information regarding hydraulic fracture design, water and gas injection management, fault re-activation, wellbore stability, sand production, rock mechanical properties, casing string design, cap and base rock integrity and gas storage design. Geomechanical and operational parameters such as, elastic properties, poro-elasticity, rock strength, formation pore pressure, far field horizontal stress, permeability/porosity distributions, borehole fluid properties among others, influences the performance of the Mini-Frac Jobs. In many cases poor understanding of the reservoir response to the fracture process, caused that the hydraulic fracture did not propagate deep into the formation. In other cases the pressure applied to the formation might be insufficient to break down the formation, leading to unsatisfactory application of the Mini-Fracture technique in the process. The objective of this thesis is to develop a Mini-Facture application simulator that uses the geomechanical and operational parameters that control the performance of a Mini-Fracture job and estimate the possibility of the occurrence of a tensile failure in the formation. The simulator is then validated by comparing its output with the results of stress test done in the field. With this simulator petrotechnical professionals and field engineers will have a platform that simulates the pressure responses and fracture initialization during Mini-Frac treatments, incorporating all the variables affecting a Wireline Mini-Fracture job, helping the design engineer to make key decisions about the ultimate or required fracture plan. Furthermore the simulator will reduce the uncertainties that limit the reliability of the Wireline Mini-Fracture treatment by allowing the selection of appropriate tool configuration based on the job objectives and the geological environmental conditions. Finally this project demonstrates that combining the appropriate constitutive relations that reflect the coupling among the tool operational performance with wellbore flow, reservoir and geomechanics modelling a Mini-Fracture simulator can be developed.Petroleum EngineeringGeoscience & EngineeringCivil Engineering and Geoscience
Information Technology: Equalizer or Separator of Developing Countries?
No full textThe author discusses about the Information technology scenario in developing countries
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