10 research outputs found

    Drag as a Resource: Trans* & Non-Binary Individuals Use of Drag in the Southeastern United States

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    Interview by Andrelisa Livingston. Author Baker Rogers discusses their article published in the December 2018 issue of Gender & Society, “Drag as a Resource: Trans* & Non-Binary Individuals Use of Drag in the Southeastern United States.”https://digitalcommons.georgiasouthern.edu/soc-anth-facaudio/1000/thumbnail.jp

    [Condemnation of Japanese American reparations]

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    Copy of a flyer, distributed by Lillian Baker, of a letter by Brigadier General A. W. Beeman written on behalf of Americans for a Sound Foreign Policy vigorously condemning Japanese American reparations.The Japanese American Relocation Collection is composed of ephemera related to the relocation program during World War II. Items include the official government report of Manzanar Relocation Center, a photo album, post-war activism materials related to preserving and remembering the camps, various clippings, and documents. The strength of this collection is found in its many perspectives on the controversial relocation program and how it has been presented since World War II

    [Newspaper clipping titled:] Dear Abby: party nearly over for alcoholic mate

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    Lillian Baker sends in letter to Dear Abby informing the writer and readers that using the term "concentration camp" to describe Japanese American incarceration camps is disrespectful to what happened to Jewish people during World War II. A newspaper clipping published in "Los Angeles times" on February 19, 1981.The Japanese American Relocation Collection is composed of ephemera related to the relocation program during World War II. Items include the official government report of Manzanar Relocation Center, a photo album, post-war activism materials related to preserving and remembering the camps, various clippings, and documents. The strength of this collection is found in its many perspectives on the controversial relocation program and how it has been presented since World War II

    Data Cleaning for Deterministic Data Linkage for Sports and Recreational Injuries Using ICD-9 and ICD-9-CM

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    We have included SAS syntax examples for cleaning emergency department and inpatient hospital data from 2006 to 2012 (in ICD-9-CM) format from the Florida Agency for Healthcare Administration. The provided syntax (in .sas format and .py format), demonstrates how we took original data sets, restricted it to specific variables, reformatted it for our purposes, and transposed it to create two separate data sets that were then merged together to create an all-encompassing data set for individual level analysis. Syntax covered under GPL-3.0-or-later. In addition, we have provided figures (author Baker) demonstrating the linkage process. One figure (Titled Figure 7) shows the steps to put together data from several years and retain all variables. The second figure (Titled Figure 8) shows the steps to take the final data sets created in Figure 7 and then create one master data set using merging. The figures are covered under a CC-BY-SA-4.0 license. </p

    Organizational endorsements for redress

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    List of major organizational endorsements for Japanese American Citizens' League's legislative campaign for redress paired with footnotes, annotations, and commentary by Lillian Baker focusing on on Min Yasui, disputing civilian incarceration, and questioning whether the reader supports fascism by supporting the listed organizations.The Japanese American Relocation Collection is composed of ephemera related to the relocation program during World War II. Items include the official government report of Manzanar Relocation Center, a photo album, post-war activism materials related to preserving and remembering the camps, various clippings, and documents. The strength of this collection is found in its many perspectives on the controversial relocation program and how it has been presented since World War II

    The role of the derivatives market in ensuring financial sustainability.

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    Currently, investing in derivative financial instruments, especially those related to sustainable financial investments, is highly popular not only in Lithuania in world also. This growth is strongly supported by significant changes at the highest level, particularly at the European Union level. In 2021, the European Commission adopted a regulation establishing the action plan for sustainable growth financing (EU, 2021). The primary objective of this plan is to direct capital flows towards sustainable investments, a crucial step in achieving the EU and global governments' goal of achieving net-zero carbon emissions by 2050. The most crucial aspect of this investment is related to ESG (Environmental, Social, Governance) conditions. ESG conditions become essential not only from an environmental perspective but also from social and governance perspectives. Investors must be informed about what constitutes sustainable derivative financial instruments and how they align with these conditions. This is necessary to create a growing economy detached from the use of fossil fuels. Author Baker (2022) examines how derivative financial instruments meet ESG conditions and how risks associated with derivative financial instruments complying with how ESG conditions are managed. Understanding the composition of these financial instruments and their impact on sustainability in the short and long term allows for more effective risk management. The analysis in the study will focus on companies' results and the use of derivative financial instruments to reveal whether companies actively implement sustainability principles. This analysis is highly relevant in today's context, where investors increasingly value companies' commitments to sustainability. The evaluation will be conducted based on projected company results, using multiple regressions to discern the impact of sustainability. Ultimately, it is crucial to note that financial instruments must not only be profitable but also environmentally friendly. This aligns with the interests of not only the present but also future generations, aiming for long-term ecological and financial sustainability

    Diverse Regulation of Cardiac Expression of Relaxin Receptor by alpha(1)- and beta(1)-Adrenoceptors

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    Relaxin, a new drug for heart failure therapy, exerts its cardiac actions through relaxin family peptide receptor 1 (RXFP1). Factors regulating RXFP1 expression remain unknown. We have investigated effects of activation of adrenoceptors (AR), an important modulator in the development and prognosis of heart failure, on expression of RXFP1 in rat cardiomyocytes and mouse left ventricles (LV). Expression of RXFP1 at mRNA (real-time PCR) and protein levels (immunoblotting) was measured in cardiomyocytes treated with alpha- and beta-AR agonists or antagonists. RXFP1 expression was also determined in the LV of transgenic mouse strains with cardiac-restricted overexpression of alpha(1A)-, alpha(1B)- or beta(2)-AR. Specific inhibitors were used to explore signal pathways involved in alpha(1)-AR mediated regulation of RXFP1 in cardiomyocytes. In cultured cardiomyocytes, alpha(1)-AR stimulation resulted in 2-3 fold increase in RXFP1 mRNA (P &lt; 0.001), which was blocked by specific inhibitors for protein kinase C (PKC) or mitogen-activated protein kinases/extracellular signal-regulated kinases (MAPK/ERK). Activation of beta(1)-, but not beta(2)-AR, significantly inhibited RXFP1 expression (P &lt; 0.001). Relative to respective wild-type controls, RXFP1 mRNA levels in the LV of mice overexpressing alpha(1A)- or alpha(1B)-AR were increased by 3- or 10-fold, respectively, but unchanged in beta(2)-AR transgenic hearts. Upregulation by alpha(1)-AR stimulation RXFP1 expression was confirmed at protein levels both in vitro and in vivo. Expression of RXFP1 was up-regulated by alpha(1)-AR but suppressed by beta-AR, mainly beta(1)-AR subtype, in cardiomyocytes. Future studies are warranted to characterize the functional significance of such regulation, especially in the setting of heart failure.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000338639900005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Cardiac &amp; Cardiovascular SystemsPharmacology &amp; PharmacySCI(E)[email protected]

    An Investigation into the Impact of Mission Statements on School Development Planning.

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    This thesis uses quantitative as well as qualitative methods to examine the impact of school philosophical statements on school development planning. Three case study schools from an Asian city were selected. A questionnaire and face to face interviews were used as data gathering tools. The data from the questionnaires informed the questions created for the interviews and the outcomes of these two data sources were analysed qualitatively. As a result of the findings from qualitative analysis a further quantitative analysis was made of the questionnaire data. A total of 188 responses to questionnaires were examined and 22 interviews took place. The main aim of this research is to empirically examine the assumptions that underpin the Council of International Schools and New England Association of Schools and College’s accreditation standards for school philosophical statements and development planning. At the heart of these assumptions is the belief that school development planning is most effective when it is closely linked to a clearly written, collaboratively created set of philosophical statements which articulate the school’s values and beliefs. To date this assumption has not been substantiated by research. A secondary aim is to examine the systems and structures in schools that assist in linking the school’s philosophy to its planning processes. The data resulted in a set of interesting findings. Firstly, insights were gained into techniques used to reaffirm and embed school philosophy into the school’s culture. Secondly, the data suggested that the assumptions made by the accrediting agencies hold true under certain circumstances but that a school’s underlying ideology may be more powerful in driving institutional planning. As a result of the findings, suggestions to further develop accreditation standards are made and ideas for further research are proposed

    The GIANT study, a cluster-randomised controlled trial of efficacy of education of doctors about type 2 diabetes mellitus management guidelines in primary care practice

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    Objectives: Primary aim: does general practitioner (GP) education on type 2 diabetes treatment improve HbA1c? Secondary aim: cardiovascular risk factors, hypoglycaemia, treatment intensification, health service utilisation, treatment barriers. Methods: 99 Asia-Pacific GPs were cluster-randomised to be educated on regional diabetes management guidelines (intervention) or continue standard care (control). The intervention employed meetings, reminders, medical record summary sheets and patient result cards. Each GP recruited four type 2 diabetic patients, assessed at baseline, 6 and 12 months. The primary outcome was mean change in HbA1c from 0 to 6 months in patients with baseline HbA1c &gt;= 6.5%. Results: 361 patients (93%) completed 6 month follow-up. The primary HbA1c outcome was 0.11% (95% CI 0.27, 0.05) with intervention and 0.22% (95% CI 0.39, 0.05) in the control group (p = 0.340). The groups did not differ in control of other glycaemic indices, blood pressure or lipids after 6 or 12 months. In those with HbA1c &gt;= 9.0%, approximately 50% received intensified treatment by 6 months, and 30% in the final 6 months. GPs identified treatment costs and patient reluctance to use insulin as management barriers. Conclusions/interpretation: A structured GP education programme did not improve HbA1c in patients with type 2 diabetes. (C) 2012 Elsevier Ireland Ltd. All rights reserved.Endocrinology &amp; MetabolismSCI(E)3ARTICLE138-459

    Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics

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    Background: Quantitative molecular data from urine are rare in epidemiology and genetics. NMR spectroscopy could provide these data in high throughput, and it has already been applied in epidemiological settings to analyse urine samples. However, quantitative protocols for large-scale applications are not available. Methods: We describe in detail how to prepare urine samples and perform NMR experiments to obtain quantitative metabolic information. Semi-automated quantitative line shape fitting analyses were set up for 43 metabolites and applied to data from various analytical test samples and from 1004 individuals from a population-based epidemiological cohort. Novel analyses on how urine metabolites associate with quantitative serum NMR metabolomics data (61 metabolic measures; n = 995) were performed. In addition, confirmatory genome-wide analyses of urine metabolites were conducted (n = 578). The fully automated quantitative regression-based spectral analysis is demonstrated for creatinine and glucose (n = 4548). Results: Intra-assay metabolite variations were mostly <5%, indicating high robustness and accuracy of urine NMR spectroscopy methodology per se. Intra-individual metabolite variations were large, ranging from 6% to 194%. However, population-based inter-individual metabolite variations were even larger (from 14% to 1655%), providing a sound base for epidemiological applications. Metabolic associations between urine and serum were found to be clearly weaker than those within serum and within urine, indicating that urinary metabolomics data provide independent metabolic information. Two previous genome-wide hits for formate and 2-hydroxyisobutyrate were replicated at genome-wide significance. Conclusion: Quantitative urine metabolomics data suggest broad novelty for systems epidemiology. A roadmap for an open access methodology is provided
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