1,099 research outputs found
Marriage record of Keno, Green and Baker, Rosa
No full textMarriage license for Green Keno and Rosa Baker. D.A. Perrin was the officiant
Perrin numbers expressible as sums of two base b repdigits
No full textIn this paper we study Perrin numbers that can be expressed as sums of two base b repdigits. This can be done using linear forms in logarithms of algebraic numbers and a version of the Baker–Davenport reduction method
Perrin Numbers That Are Concatenations of a Perrin Number and a Padovan Number in Base b
No full textLet (Formula presented.) be a Padovan sequence and (Formula presented.) be a Perrin sequence. Let n, m, b, and k be non-negative integers, where (Formula presented.). In this paper, we are devoted to delving into the equations (Formula presented.) and (Formula presented.), where d is the number of digits of (Formula presented.) or (Formula presented.) in base b. We show that the sets of solutions are (Formula presented.) (Formula presented.) for the first equation and (Formula presented.) for the second equation. Our approach employs advanced techniques in Diophantine analysis, including linear forms in logarithms, continued fractions, and the properties of Padovan and Perrin sequences in base b. We investigate both the deep structural symmetries and the complex structures that connect recurrence relations and logarithmic forms within Diophantine equations involving special number sequences. © 2025 by the author
L’action ou la contemplation. Note sur la relation de la fille de Thrace au Docteur angélique
No full textIf the opposition between “action and contemplation” seems characteristic of the history of philosophy, it also sums up Hannah Arendt’s personal history and philosophy – the diagnosis of the theoretician of the political practice on her contemporaries being eloquent. But the author of the Human condition invites us to reverse the conjunction. Arendt breaks up deliberately with philosophical tradition and particularly with Thomas Aquinas by making these terms exclusive and choosing to think either action (without contemplation) or contemplation (without action). We would like thus to reflect on the relationship between these two thinkers by examining potential echoes of Summa Theologiae within Arendt’s 1958 essay
Overdose : Heartbreak and hope in Canada's opioid crisis
No full textProfessor Perrin’s research covers issues related to victims of crime, and the opioid crisis. He is an advocate for compassionate, evidence-based approaches to pressing criminal justice and societal issues. Professor Perrin is the author of numerous law review articles and provides commentary in the media. His books include Overdose: Heartbreak and Hope in Canada’s Opioid Crisis (2020), Victim Law: The Law of Victims of Crime in Canada (2017) and Invisible Chains: Canada’s Underground World of Human Trafficking (2011). Professor Perrin joined UBC after serving as a law clerk at the Supreme Court of Canada and advising judges at the International Criminal Tribunal for the former Yugoslavia and Special Court for the Sierra Leone. He was lead criminal justice advisor and in-house legal counsel to the Prime Minister of Canada.Law, Peter A. Allard School ofUnreviewedFacult
Investigating the Mechanisms and Specificities of BphI-BphJ, an Aldolase-Dehydrogenase Complex From Burkholderia xenovorans LB400
No full textChapter 3 - Reprinted (adapted) with permission from Baker, P., Carere, J., and Seah, S. Y. (2011) Probing the Molecular Basis of Substrate Specificity, Stereospecificity, and Catalysis in the Class II Pyruvate Aldolase, BphI, Biochemistry 50: 3559-3569. Copyright (2011) American Chemical Society. Chapter 4 - Reprinted (adapted) with permission from Baker, P., and Seah, S. Y. (2012) Rational design of stereoselectivity in the class II pyruvate aldolase BphI, J Am Chem Soc 134: 507-513. Copyright (2012) American Chemical Society. Chapter 6 - Reprinted (adapted) with permission from Baker, P., Hillis, C., Carere, J., and Seah, S. Y. (2012) Protein-protein interactions and substrate channeling in orthologous and chimeric aldolase-dehydrogenase complexes, Biochemistry 51: 1942-1952. Copyright (2012) American Chemical Society.Microbial degradation of aromatic hydrocarbons is imperative for maintaining the global carbon cycle and removing potentially toxic aromatic xenobiotics. This thesis focuses on the characterization of a pyruvate-specific class II aldolase (BphI) and acetaldehyde dehydrogenase (BphJ), the final two enzymes of the bph meta-cleavage pathway in Burkholderia xenovorans LB400. This pathway is responsible for the degradation of the industrial pollutant polychlorinated biphenyls (PCB) and therefore mechanistic characterization of these enzymes can be applied to improve pollutant degradation. BphI catalyzes the aldol cleavage of 4-hydroxy-2-oxoacids to pyruvate and an aldehyde while BphJ transforms aldehydes to acyl-CoA, using NAD+ and CoASH as cofactors. Size-exclusion chromatography was used to determine that the oligomeric unit of the BphI-BphJ complex is a heterotetramer. The aldolase BphI was shown to exhibit a compulsory order mechanism and utilize 4-hydroxy-2-oxoacids with an S configuration at C4. The generation of BphI active site variants allowed for the proposal of a catalytic mechanism and a greater understanding as to how stereospecificity occurs. Using steady-state kinetic assays, Arg-16 was demonstrated to be essential for catalysis. Molecular modeling of the substrate and pH dependency (wild-type pKa of ~7, lost in H20A and H20S variants) were used to identify His-20 as the catalytic base. Tyr-290 was originally proposed to be the catalytic acid. However, this was refuted as a Tyr-290 (Y290F) variant did not affect the catalytic efficiency of the enzyme. Instead, the variant was observed to exhibit a loss of stereochemical control. From the crystal structure of an orthologous aldolase-dehydrogenase complex, solvent isotope effect studies, and a proton inventory, a water molecule was implicated as the catalytic acid. Based on their position within the crystal structure, Leu-87 and Leu-89 were implicated in substrate specificity. Replacement of Leu-89 with alanine effectively increased the length of the active site, allowing for the accommodation of longer aldehyde substrates. In contrast, Leu-87 was responsible for hydrophobic stabilization of the C4-methyl of the substrate. Double variants L87N;Y290F and L87W;Y290F were constructed to enable the binding of 4(R)-hydroxy-2-oxoacids. Polarimetric analysis confirmed that the double variants were able to synthesize 4-hydroxy-2-oxoacids of up to 8 carbons in lengths, which were of the opposite stereoisomer to those produced by the wild-type enzyme. Cys-131 was identified as the catalytic thiol that forms an acyl-enzyme intermediate in the dehydrogenase, BphJ. This enzyme was shown to exhibit similar specificity constants for acetaldehyde and propionaldehyde and utilize aliphatic aldehydes from two to five carbons in length as substrates. The enzyme was able to use either NAD+ or NADP+ as the cofactor. Finally, we demonstrated that aldehydes produced in the aldolase reaction are not released into the bulk solvent but are channeled directly to the dehydrogenase, providing the first biochemical determination of substrate channeling in any aldolase-dehydrogenase complex.Natural Sciences and Engineering Research Council of CanadaOntario Graduate Scholarship in Science and Technolog
Recent Decisions
No full textComments on recent decisions by Sidney Baker, Arthur L. Beaudette, Mark Harry Berens, Francis W. Collopy, Patrick F. Coughlin, Benedict R. Danko, Joseph M. Gaydos, William T. Huston, Francis J. Keating, John E. Lindberg, James D. Matthews, Lawrence S. May, Jr., Maurice J. Moriarty, George J. Murphy, Jr., William J. O\u27Connor, Charles James Perrin, Albert R. Ritcher, Henry Martin Shine, Jr., Cyril C. Vidra, and Dale A. Winnie
Recent Decisions
No full textComments on recent decisions by Sidney Baker, Arthur L. Beaudette, Mark Harry Berens, Francis W. Collopy, Patrick F. Coughlin, Benedict R. Danko, Joseph M. Gaydos, William T. Huston, Francis J. Keating, John E. Lindberg, James D. Matthews, Lawrence S. May, Jr., Maurice J. Moriarty, George J. Murphy, Jr., William J. O\u27Connor, Charles James Perrin, Albert R. Ritcher, Henry Martin Shine, Jr., Cyril C. Vidra, and Dale A. Winnie
Larinus crassiusculus Desbrochers 1895
No full textLarinus crassiusculus Desbrochers, 1895 Larinus crassiusculus Desbrochers, 1895: 93 In the description, Desbrochers indicates “Long. 910; lat. 56 mill.” and “Akbẻs, rapportẻ par M. Delagrange de qui je l’ai reçu, ainsi que de MM. Staudinger et BangHaas”. Types. The male designated as lectotype bears the labels “ Syrie, Akbes, C.D. 1891 ” [printed, C.D. for Ch. Delagrange] and “ crassiusculus Db, 1.80 ”, “ type ” [handwritten] and has been labelled “ Lectotypus ɗ, Larinus crassiusculus Desbr., Gültekin & Perrin des. 2004 ” [printed on red paper]. Four other males and one female in Desbrochers’ collection are designated as paralectotypes and labelled accordingly as “ Paralectotypus ɗ/Ψ, Larinus crassiusculus Desbr., Gültekin & Perrin des. 2004 ” [printed on red paper]: female pinned through right elytron and intact “[golden square label]”, “ crassiusculus m.” [handwritten]; male pinned through right elytron and with right middle tibia and tarsus, half part of third segment and claw segments of the fore left tarsus and left hind tarsus missing “[golden square label]”; male pinned through right elytron and intact “ Syrie, Akbes, C.D. 1891 ” [printed]; male pinned through right elytron and with left hind leg missing “ Syrie, Akbes, C.D. 1891 ” [printed]; male pinned through right elytron and intact “ Syrie, Akbẻs, Ch. Delagrange, Etẻ 1890 ” [printed]. Another male in the “M. Pic, ex. Delagrange” collection, pinned through right elytron and with hind left leg missing and labelled “ Syrie, Akbes, Cd. 1891 ” [printed], “[pink rounded label]”, “ crassiusculus m.” “ Type ” [printed on red paper] is also designated as paralectotype and labelled “ Paralectotypus ɗ, Larinus crassiusculus Desbr., Gültekin & Perrin des. 2004 ” [on red paper]. Another male standing under the name crassiusculus together with the syntypes does not belong to the type series, having been collected two years after the description of the species, in southern Turkey (labelled “ Asia minor, Gülek, Taur. Cilic., 1897, Holtz”). Remarks. Larinus khnzoriani TerMinassian, 1962 is conspecific with Larinus crassiusculus Desbrochers, 1895, the types of both having been examined by the senior author. Thus, the following new synonymy is here proposed: Larinus crassiusculus Desbrochers, 1895 [= Larinus khnzoriani TerMinassian, 1962 syn. n.]. This species is related to L. curtus Hochhuth, 1851 and L. palaestinus Talamelli, 1999. A redescription of it is in preparation for a forthcoming revision of some species groups of Larinus.Published as part of Gültekin, Levent & Perrin, Hélène, 2006, The species of Larinus Dejean, 1821 (Coleoptera: Curculionidae) described by J. Desbrochers: lectotype designations and new synonymies, pp. 55-68 in Zootaxa 1350 on page 61, DOI: 10.5281/zenodo.27359
Larinus cribricollis Desbrochers 1896
No full textLarinus cribricollis Desbrochers, 1896 Larinus cribricollis Desbrochers, 1896: 66 In the description, Desbrochers indicates “Long. 10 mill.” and “ Syrie ”. Type. The female recognized as holotype bears the handwritten labels “ Syrie ”, “ L. cribricollis, Fr. 96 V 60 5 ” and “ type ” and has been labelled “ Holotypus Ψ, Larinus cribricollis Desbr., Gültekin & Perrin des. 2005 ” [on red paper], “ Larinus lederi Fst, L. Gültekin det. 2005 ”. It misses the left middle tarsus beyond the first segment and the left antenna. Remarks. The mention “Fr. 96 V 60 5 ” is a reference to the description [probably 60 5, a mistake for 65, the number for this species in the Desbrochers’ note]. Larinus cribricollis Desbrochers, 1896 is conspecific with Larinus lederi Faust, 1889, the types of both having been examined by the senior author, necessitating the following new synonymy: Larinus lederi Faust, 1889 [= Larinus cribricollis Desbrochers, 1896 syn. n.].Published as part of Gültekin, Levent & Perrin, Hélène, 2006, The species of Larinus Dejean, 1821 (Coleoptera: Curculionidae) described by J. Desbrochers: lectotype designations and new synonymies, pp. 55-68 in Zootaxa 1350 on page 63, DOI: 10.5281/zenodo.27359
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