4,154 research outputs found

    Portraits of Friends and Acquaintances, L to R: Martha Jane Bailey, Mary Hoggard, Nancy A.E. McLendon (sister of Martha Jane Bailey)

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    Black and white photograph of three women. Left to right: Martha Jane Bailey, Mary Hoggard and Nancy A.E. McLendon- sister of Martha Jane Bailey

    Persistent hyperammonemia in two related Morgan weanlings

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    Persistent hyperammonemia was diagnosed in 2 Morgan fillies with clinical signs that developed early in the postweaning period. Diagnostic evaluation, including routine serum chemistries, CBC, liver biopsy, hepatic ultrasonography, liver function test, and necropsy findings did not support a toxic, developmental, or infectious cause. Abnormal serum amino acid and urine orotic acid concentrations suggest that the foals may have had an inherited disorders described in humans as hyperornithinemia, hyperammonemia, and homocitrullinuria (HHH) syndrome. The disorder is thought to be caused by a defective mitochondrial transporter protein, such that ornithine, required for complete urea synthesis, is deficient, thus causing increases in blood ammonia and ornithine concentrations.LR: 20061115; PUBM: Print; JID: 8708660; 0 (Amino Acids); 7006-33-9 (Ornithine); 7664-41-7 (Ammonia); ppublishSource type: Electronic(1

    Book Review: “If That Small Sparke Could Yield So Great a Fire”: Morgan Lloyd Malcolm’s Emilia and Eugenie Freed’s A Several Plot

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    Book Title: A Several PlotBook Author: Eugenie Freed(Johannesburg: Eugenie R. Freed, 2017)Book Title: EmiliaBook Author: Morgan Lloyd Malcolm(London: Oberon, 2018

    Can health trainers make a difference with difficult-to-engage clients? A multisite case study

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    A political attempt in the United Kingdom to address health inequalities in the past decade has been the government’s initiative to employ local health trainers (HTs) or health trainer champions (HTCs) to support disadvantaged individuals with aspects of their health-related behaviors. HT/HTCs provide health-related information and support to individuals with healthy eating, physical activity, and smoking cessation. They undertake community engagement and direct individuals to relevant health services. They differ in that HTs are trained to provide health interventions to individuals or groups and to make referrals to specialist health care services when necessary. This article provides an evaluation of HT/HTCs interventions across three sites, including one prison, one probation service (three teams), and one mental health center. An evaluation framework combining process and outcome measures was employed that used mixed methods to capture data relating to the implementation of the service, including the context of the HT/HTCs interventions, the reactions of their clients, and the outcomes reported. It was found that HT/HTCs interventions were more effective in the prison and mental health center compared with the probation site largely as a result of contextual factors

    Nested row-column designs for near-factorial experiments with two treatment factors and one control treatment

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    The authors also thank Queen Mary, University of London, the University of St Andrews and the Poznan University of Life Sciences for financial support. The second author was also supported by the British-Polish Young Scientists Programme, grant WAR/342/116.This paper presents some methods of designing experiments in a block design with nested rows and columns. The treatments consist of all combinations of levels of two treatment factors, with an additional control treatment.Peer reviewe

    J. R. R. Tolkien, ecology, and education

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    John Ronald Reul Tolkien (1892-1973) was an Oxford trained philologist, professor (don) at Oxford, noted scholar, and author of high fantasy literature. His The Lord of the Rings trilogy (TLOR) has sold over 150 million copies worldwide making it the second bestselling work of fiction of all time (“The Lord of the Rings,” 2014). His popularity has resurged, though it never really waned, with Peter Jackson’s big screen adaptation of Tolkien’s most famous work The Lord of the Rings (2001-2003), also in trilogy form, winning multiple Oscar Awards, and grossing over 3 billion dollars worldwide (“The Lord of the Rings,” 2014). More recently, Jackson’s three part installments of the precursor to TLOR, The Hobbit (2012-2014), have also proved highly successful in movie format. As has been long noticed by fans and critics alike, Tolkien’s works, TLOR, The Hobbit, The Silmarillion (his legendarium of Middle-earth or Arda), and other lesser known works like The Adventures of Tom Bombadil (TATB) are permeated with ecological themes and tropes. According to Morgan (2010), Tolkien’s ecology is “[grounded in a] creation-centered ethic of stewardship . . . . that holds the potential to re-enchant the world” (p. 383). Further, Morgan (2010) also says, that “The story . . . possesses significant pedagogical potential, albeit implicit in nature" (pp. 383-384). Obviously, at least to many, the Earth is in a state of ecological crisis. My dissertation investigates ecology through select high fantasy works of J. R. R. Tolkien. Specifically, I intend to address what can be construed by studying the enigmatic character of Tom Bombadil, while giving due consideration to other characters who represent or are a party to ecological concerns. This dissertation will prove that the study of Bombadil is a boon to ecological education in the forms of autodidacticism, ecopedagogy, and ecoliteracy by showing readers how the Earth should be treated and with regard to changing our current anthropocentric mindset to one that embraces a respect and reverence for nature; that is, biophilia

    55594: Poem: 'The Battle of Gazza [sic]' by Pte JD Morgan

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    Poem written by Pte J. D. MorganSomwhere at Gazza they laid themSomewhere at Gazza they fellLittle we thought when we partedIt was our last farewellGone are the friends we loved so dearSilent the voices we love to hearThey sleep in a lonely graveThis Poem by Pte J. D. Morgan printed in the Montgomeryshire County Times 21 July 1917, is a sample from a folder of research undertaken by Mrs Jones into the men named on the war memorial (1914-1919) of Guilsfield parish (near Welshpool, Montgomeryshire - now Powys, in Wales). During the battle of Gazza in 1916 Pte Frank Arthur, Guilsfield, was wounded. He died in Palestine in 1917, and photos etc. have also been submitted from that collection. The names on the Guilsfield memorial include: Frank Arthur, Ernest Charlton, Edward Evans, Robert Evans, Fred Evans, Charles Galliers, Robert Gainsford, Edward Griffiths,John Higgins, Edwin Jones, James Jones, Charles Jones, William Jones, Alan Langlands, Edward Lloyd, John Lloyd, Richard Morgan, Edward Morris, John Owen, Evan Phillips, Herbert Trevor, David E. Bailey, Herbert Bailey, Arthur Gough, Charles Jones, George R. Jones, Arthur T. Lewis, Mathew W.H. Morris, Richard D.H. Mytton, Gruffydd V. Trevor. Representing a number of regiments of the army, also the Royal Navy and the Royal Flying Corps. Also evident is the volunteers who joined up early in the war, as well as the tribunals which decided that even though farming was a reserved occupation that man-power being so scarce some men would be compelled to join the army, leaving their families, their aging fathers, mothers, sisters and younger siblings to continue to provide food for the war effort - an insight into the home-front in rural Wales.</p

    A distributed amplifier system for bilayer lipid membrane (BLM) arrays with noise and individual offset cancellation

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    Lipid bilayer membrane (BLM) arrays are required for high throughput analysis, for example drug screening or advanced DNA sequencing. Complex microfluidic devices are being developed but these are restricted in terms of array size and structure or have integrated electronic sensing with limited noise performance. We present a compact and scalable multichannel electrophysiology platform based on a hybrid approach that combines integrated state-of-the-art microelectronics with low-cost disposable fluidics providing a platform for high-quality parallel single ion channel recording. Specifically, we have developed a new integrated circuit amplifier based on a novel noise cancellation scheme that eliminates flicker noise derived from devices under test and amplifiers. The system is demonstrated through the simultaneous recording of ion channel activity from eight bilayer membranes. The platform is scalable and could be extended to much larger array sizes, limited only by electronic data decimation and communication capabilities

    Postvocalic /r/ in New Orleans: Language, place and commodification

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    From silva dimes to po-boys, r-lessness has long been a conspicuous feature of all dialects of New Orleans English. This dissertation presents a quantitative and qualitative description of current rates of r-lessness in the city. 71 speakers from 21 neighborhoods were interviewed. R-pronunciation was elicited in four contexts: interview chat, Katrina narratives, a reading passage and a word list. R-lessness was found in 39% of possible instances. Older speakers pronounce /-r/ less than younger speakers, and those with a high school education or less pronounce /-r/ far less than those with post-secondary education. Race and gender did not prove to be significant predictors of r-pronunciation. In contrast to past studies, many speakers in the current study discuss their metalinguistic awareness of /-r/ and their partial control of /-r/ variation, discussing switching between r-fulness and r-lessness in different contexts. In New Orleans, this metalinguistic awareness is attributable in part to the devastation following Hurricane Katrina in 2005, when the near-disappearance of the city intensified an already extant nostalgia for local culture, including ways of speaking. Nostalgia and amplification by advertisers and popular media have helped recontextualize r-lessness as a variable associated with a number of social meanings, including localness and authenticity. These processes help transform r-lessness, for many speakers, from a routine feature of talk to a floating cultural variable, serving as a semiotic resource on which speakers can draw on to perform localness. This dissertation both closes a gap in research on New Orleans speech and uses New Orleans as a case study to suggest that the social meanings of linguistic features are created and maintained in part by a constellation of interrelated social processes of late modernity. Further, I argue that individual speakers are increasingly agentively engaged with these larger processes, as part of a global transformation from more traditional, place-bound populations to more deracinated individuals who choose to align themselves with particular communities and local cultural forms, particularly those that have been commodified

    An Agent-Based Framework to Support Adaptive Hypermedia

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    The field of adaptive hypermedia is a little over a decade old. It has a rich history in a range of fields such as artificial intelligence, user modelling, intelligent tutoring systems and hypertext. Early adaptive hypermedia work concentrated on application-led research; developing a range of systems for specific purposes. In 1996, Peter Brusilovsky reviewed the state-of-the-art and proposed a taxonomy of adaptive hypermedia techniques, thereby providing the means to categorise adaptive hypermedia systems. Since then, several practical frameworks for adaptive hypermedia applications have been produced, in addition to formal models for formalising adaptive hypermedia applications. This thesis presents a new framework for adaptive hypermedia systems based on agent technology, a field of research largely ignored within the adaptive community. Conceptually, this framework occupies a middle ground between the formal reference models for adaptive hypermedia and application-specific frameworks. This framework provides the means to implement formal models using variety of architectural approaches. Three novel adaptive hypermedia applications have been developed around this agent-based framework. Each system employs different architectural structures, they model the user with a variety of profiling techniques, and each provides a different set of adaptive features. The diversity of these three systems emphasises the flexibility and functionality of this proposed agent-based framework
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