28 research outputs found
The elusive bigness of Bakema
No full textGreen Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Space & Typ
Architecture and democracy: Contestations in and of the open society
No full textIn many ways the work and ideas of Jaap Bakema epitomize the best of the architecture of the post-war Dutch welfare state: it is utterly unapologetic about its modernity as well as its drive to be universal and egalitarian. Bakema firmlypositioned his office and its production at the heart of the Dutch welfare state system. Not only did he, together with his office partner Jo van den Broek, succeed in developing a systemized approach towards housing and planning,integrated design, construction, and advanced typological research, he also presented the construction of the Dutch welfare state as the opportunity par excellence to recast Dutch society as a forward-looking, humane, modern andrationalist welfare state society within the new global reality of the Cold War.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Space & Typ
Vocabulary of hospitality
No full textAttitudes about refugees begin with the words we ascribe them. In Turkey – which has historically absorbed newcomers from a variety of outside conflicts – the term ‘guest’ is commonly used. Taking this as a starting point, Merve Bedir questions the laws of hospitality in Turkey, and the inherent hostility embedded in the word. She argues for a heightened understanding of the vocabulary around refugees, as a necessary first step to an improved refugee policy.Architectural Engineering +TechnologyArchitecture and The Built Environmen
Asylum seekers and refugees in Turkey: A continuous state of exception
No full textAs the borders of Europe slowly expand to include Turkey, the country finds itself in the position of having to strengthen its own walls. With the continuing conflict in Syria, this issue has become urgent. Merve Bedir traces the last 100 years of migration in Turkey, and how it has dealt with varying flows of refugees and immigrants. Away from the refugee camp with its clear borders and rations, Bedir questions the condition of the urban refugee, a precarious existence within a state of exception, and to what degree resistance might be possible.Architectural Engineering +TechnologyArchitecture and The Built Environmen
Kinetic Modeling of Magnetic Field Dynamics and Thermal Energy Transport in Inertial Fusion Energy Plasmas.
No full textIn indirect-drive inertial-fusion experiments, a hohlraum converts laser energy into X-rays that heat an ablator material on a fuel capsule. The expansion of the ablator leads to implosion of the fuel capsule and fusion conditions in a hot spot, where alpha particles are produced and propagate a burn wave through the fuel. Accurate determination of the balance of energy fluxes in the hohlraum not only requires consideration of X-ray transport, but also needs careful treatment of electron transport, because laser energy is coupled primarily to the electrons in the plasma. The steep electron-thermal-energy gradients in this environment can lead to breakdown of diffusive heat-transport and introduce non-local effects. Additionally, the plasmas produced in such laser-plasma experiments are subject to the influence of self-generated magnetic fields. A kinetic formulation enables detailed calculations of thermal-energy transport and magnetic-field dynamics in these plasmas due to self-consistent inclusion of effects in electron transport that depend not only on details of the particle energy distribution but also on the electromagnetic fields in the plasma. The dissertation describes novel comparisons between Braginskii transport and kinetic modeling that quantify the importance of kinetic effects. In addition to the theoretical contributions and modeling results, the author was also responsible for the development of a ray-tracing module to model laser propagation.
Through kinetic modeling, the heat flow near the laser heating region retains non-local effects. In the case of an externally applied magnetic field, non-local contributions to the Nernst effect increase the rate of field transport by the Nernst mechanism. The Nernst effect leads to significantly faster transport of the magnetic field to the hohlraum axis in comparison to field transport through plasma hydrodynamic motion only.
The self-generated magnetic fields are oppositely aligned with respect to each other and and are subject to reconnection. The magnetic reconnection mechanism is, in this case, governed by heat flow that transports the magnetic field. This mechanism is prevalent in plasmas where the thermal energy density is higher than the magnetic energy density. Such an environment is present in hohlraums near the critical surface, where reconnection results in redistribution of the thermal energy.PhDNuclear Engineering and Radiological SciencesUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/120806/1/archisj_1.pd
Water, Sanitation and the Modern City: Colonial and Post-colonial Experiences in Lagos and Mumbai
No full texthuman development, water, sanitation
Manufacturing urbanism: an architectural practice for unfinished cities
No full textThis PhD is a reflection upon an architectural practice developed over twelve years, incorporating architectural design, teaching and writing. The practice consists of a variety of projects ranging from full-scale architectural interventions to speculative urban proposals, and includes individually authored work alongside collaborations with an international network of practitioners and academics. Addressing this constellation of projects and approaches, the reflective process of this PhD served to identify two primary conceptual domains and drivers of the work: contemporary industrial manufacturing and urban transformation. The culmination of the research models a vehicle for future practice situated between these domains, predicated strongly on methods of prototyping and strategic incentivisation in the urban realm. A core agenda of the work is a predilection for, and prioritisation of, incompleteness in architectural design, structures of professional practice and urbanism. The research, presented through a written document and exhibition, is structured in five parts:1. Staging Practices: case studies in how experimental design practices inform and redefine professional ones.2. Industrial Practices: experiments with materials and methods of manufacturing in architectural work.3. Urban Practices: documenting qualities of urbanism between phases of industrial or economic change.4. Networked Practices: architectural experiments between manufacturing and urbanism.5. Modelling a Future Practice: a platform for collaborative architectural practice at the intersection of urban/economic and industrial/material concerns
Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution
No full textGTP is a major regulator of multiple cellular processes, but tools for quantitative evaluation of GTP levels in live cells have not been available. We report the development and characterization of genetically encoded GTP sensors, which we constructed by inserting a circularly permuted yellow fluorescent protein (cpYFP) into a region of the bacterial G protein FeoB that undergoes a GTP-driven conformational change. GTP binding to these sensors results in a ratiometric change in their fluorescence, thereby providing an internally normalized response to changes in GTP levels while minimally perturbing those levels. Mutations introduced into FeoB to alter its affinity for GTP created a series of sensors with a wide dynamic range. Critically, in mammalian cells the sensors showed consistent changes in ratiometric signal upon depletion or restoration of GTP pools. We show that these GTP evaluators (GEVALs) are suitable for detection of spatiotemporal changes in GTP levels in living cells and for high-throughput screening of molecules that modulate GTP levels
Supplementary Figures and Legends from Immunosuppressive Myeloid Cells Induce Nitric Oxide–Dependent DNA Damage and p53 Pathway Activation in CD8<sup>+</sup> T Cells
No full textSupplementary Figures 1-8 with Legends included</p
XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response
No full text
