267,201 research outputs found
On the flocks of Q+(3,q)
No full textsi prova che i flock di Q+(3,q) sono tutti e soli quelli noti, cioe' i flock lineari, i flock di Thas e gli esempi sporadici costruiti da L. Bader. Questo comporta la classificazione dei piani di traslazione di ordine q^2 aventi nucleo contenente GF(q) e provenienti da una fibrazione costituita da regoli con due rette in comune. Applicando la suddetta classificazione, si dimostra anche che non esistono MES per q diverso da 11,23,5
Shelby County v. Holder (2013): la dissenting opinion di Ruth Bader Ginsburg
No full textLa dissenting opinion della giudice Ruth Bader Ginsburg nella sentenza Shelby County v. Holder (2013), è l’emblema del suo pensiero in tema di diritti civili, in particolare del diritto di voto. L’analisi di questa complessa e densa decisione (68 pagine di cui 36 di opinione dissenziente), si articolerà dunque in alcuni passaggi. Dopo un inquadramento del caso, sono messe a confronto l’opinione di maggioranza e l’opinione dissenziente con riguardo a due aspetti, ossia, da un lato la competenza esclusiva statale in materia elettorale e la posizione di parità di tutti gli Stati (clausola dell’equal sovereignty). Dall’altro, l’analisi verte sul sindacato di ragionevolezza della scelta del Congresso di reiterare gli strumenti di controllo nei confronti soltanto di alcuni Stati membri, misure ritenute giustificate, secondo l’opinione di maggioranza, solo alla luce della situazione vigente negli anni Sessanta, ormai superata nel momento in cui il legislatore federale ha deciso di adottare l’ennesima proroga di esse. Dopodiché il contributo esamina i punti salienti dell’opinione dissenziente relativi in particolare al controllo di proporzionalità delle misure emergenziali, per soffermarsi sulle modalità di utilizzo dei dati empirici, che hanno condotto la giudice Bader Ginsburg a soluzioni diametralmente opposte rispetto a quelle cui è giunta la maggioranza del collegio, pur partendo dall’analisi dei medesimi dati
Lebertia (Pilolebertia) longiseta Bader 1955
No full text<i>Lebertia (Pilolebertia) longiseta</i> Bader, 1955 <p> <i>Lebertia longiseta</i> Bader, 1955: Mota¸s 1928f: 150, 1928g: 9.</p> <p>Distribution in France: Haute-Savoie.</p> <p> Remark: Initially reported as a <i>nomen nudum</i> by Walter (in Obermeyer 1922) and Mota¸s (1928f), but later on described by Bader (1955).</p>Published as part of <i>Smit, H. & Gerecke, R., 2010, A CHECKLIST OF THE WATER MITES OF FRANCE (ACARI: HYDRACHNIDIA) Harry S and Reinhard G, pp. 21-91 in Acarologia 50 (1)</i> on page 40, DOI: 10.1051/acarologia/20101952, <a href="http://zenodo.org/record/5392293">http://zenodo.org/record/5392293</a>
Brachychthonius gygeri Bader, 1963, sp. n.
No full text<p>Brachychthonius gygeri sp. n.</p> <p>Körpergrösse 155 x 72 µ. Propodosoma 52 µ, Hysterosoma 103 µ. Rostralhaare 16 µ, Körperhaare 12 µ. Pseudostigmatische Organe 36 µ.</p> <p>Die neue Art steht Brachychthonius berlesei Willmann, 1928 sehr nahe, vor allem in bezug auf die Körpergestalt. Sie unterscheidet sich aber von ihr durch kleinere Körper- und durch die längeren Pseudostigmatischen Organe, deren distale Hälfte zwar ebenfalls ährenartig gestaltet ist, doch aber deutlich mit grannenartigen Borsten besetzt ist, und die in eine scharfe Spitze ausläuft.</p> <p>Die Körperfarbe ist hell-strohgelb, das Hysterosoma ist gut geschultert, die Rücken- sind einfach gestaltet. Die Ornamentierung der Rückendecke des Hysterosomas ist nur durch schwache, nicht in sich geschlossene Rillen erkennbar, während auf dem Propodosoma deutliche Chitinleisten vorhanden sind, welche wallartig den äusseren Rand desselben verstärken. In ihrem Innenfeld ist eine schwach ornamentierte Fläche, die bis zu den Pseudostigmatischen Organen reicht. Die Tarsen der Beine sind mit einer einzigen, sichelförmigen, relativ grossen Kralle besetzt.</p> <p>Im Innern des Hysterosomas sind drei eierartige, durch dunklere Ausfärbung leicht erkennbare Gebilde vorhanden, von denen aber nur eines sich durch deutliche Umrisse auszeichnet und als Ei betrachtet werden darf, während die beiden anderen wahrscheinlich nur als Kotballen zu bewerten sind.</p> <p>Fundort: Basel, Botanischer Garten (Funddatum unbekannt).</p> <p>Alle Arten der Gattung Brachychthonius sind bekannt als Bewohner von Moor- und Rohhumus-Böden und von Moospolstern trockener bis nasser Standorte. Sie kommen als Parasiten der Japygiden-Zuchten nicht in Betracht, das Auftreten eines einzelnen Tieres ist nur als zufällig zu betrachten. Die Tiere ernähren sich sehr wahrscheinlich von Abbaustoffen pflanzlichen und tierischen Ursprungs.</p> <p>Das Typus-Präparat von Brachychthonius gygeri Schweizer, 1963 wird als Holotypus Nr. N P 2190 im Naturhistorischen Museum aufbewahrt.</p>Published as part of <i>Bader, C., 1963, Eine Milbendiagnose aus dem Nachlass Dr. Josef Schweizer, pp. 67-68 in Verhandlungen der Naturforschenden Gesellschaft in Basel 74</i> on pages 67-6
Stem cell mechanobiology
No full textStem cells are undifferentiated cells that are capable of proliferation, self-maintenance and differentiation towards specific cell phenotypes. These processes are controlled by a variety of cues including physicochemical factors associated with the specific mechanical environment in which the cells reside. The control of stem cell biology through mechanical factors remains poorly understood and is the focus of the developing field of mechanobiology. This review provides an insight into the current knowledge of the role of mechanical forces in the induction of differentiation of stem cells. While the details associated with individual studies are complex and typically associated with the stem cell type studied and model system adopted, certain key themes emerge. First, the differentiation process affects the mechanical properties of the cells and of specific subcellular components. Secondly, that stem cells are able to detect and respond to alterations in the stiffness of their surrounding microenvironment via induction of lineage-specific differentiation. Finally, the application of external mechanical forces to stem cells, transduced through a variety of mechanisms, can initiate and drive differentiation processes. The coalescence of these three key concepts permit the introduction of a new theory for the maintenance of stem cells and alternatively their differentiation via the concept of a stem cell 'mechano-niche', defined as a specific combination of cell mechanical properties, extracellular matrix stiffness and external mechanical cues conducive to the maintenance of the stem cell population.<br/
Biomechanical signals and the C-type natriuretic peptide counteract catabolic activities induced by IL-1? in chondrocyte/agarose constructs
No full textIntroduction: The present study examined the effect of C-type natriuretic peptide (CNP) on the anabolic and catabolic activities in chondrocyte/agarose constructs subjected to dynamic compression. Methods: Constructs were cultured under free-swelling conditions or subjected to dynamic compression with low (0.1 to 100 pM) or high concentrations (1 to 1,000 nM) of CNP, interleukin-1? (IL-1?), and/or KT-5823 (inhibits cyclic GMP-dependent protein kinase II (PKGII)). Anabolic and catabolic activities were assessed as follows: nitric oxide (NO) and prostaglandin E2 (PGE2) release, and [3H]-thymidine and 35SO4 incorporation were quantified by using biochemical assays. Gene expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), aggrecan, and collagen type II were assessed with real-time quantitative PCR (qPCR). Two-way ANOVA and the post hoc Bonferroni-corrected t tests were used to examine data. Results: CNP reduced NO and PGE2 release and partially restored [3H]-thymidine and 35SO4 incorporation in constructs cultured with IL-1?. The response was dependent on the concentration of CNP, such that 100 pM increased [3H]-thymidine incorporation (P < 0.001). This is in contrast to 35SO4 incorporation, which was enhanced with 100 or 1000 nM CNP in the presence and absence of IL-1? (P < 0.001). Stimulation by both dynamic compression and CNP and/or the PKGII inhibitor further reduced NO and PGE2 release and restored [3H]-thymidine and 35SO4 incorporation. In the presence and absence of IL-1?, the magnitude of stimulation for [3H]-thymidine and 35SO4 incorporation by dynamic compression was dependent on the concentration of CNP and the response was inhibited with the PKGII inhibitor. In addition, stimulation by CNP and/or dynamic compression reduced IL-1?-induced iNOS and COX-2 expression and restored aggrecan and collagen type II expression. The catabolic response was not further influenced with the PKGII inhibitor in IL-1?-treated constructs. Conclusions: Treatment with CNP and dynamic compression increased anabolic activities and blocked catabolic effects induced by IL-1?. The anabolic response was PKGII mediated and raises important questions about the molecular mechanisms of CNP with mechanical signals in cartilage. Therapeutic agents like CNP could be administered in conjunction with controlled exercise therapy to slow the OA disease progression and to repair damaged cartilage. The findings from this research provide the potential for developing novel agents to slow the pathophysiologic mechanisms and to treat OA in the young and old. <br/
Huth (Ferdinand Louis) Papers
No full textReceipt for 16 dollars, 25 cents paid to Joseff Bader for carriage fees and supplies, to be repaid as soon as funds arrive from France. Signed Joseff Bader on April 29, 1844 in San Antonio. "Received from Mister Louis Huth, on behalf of Mr. H[enr]i Castro in Paris.
Huth (Ferdinand Louis) Papers
No full textReceipt for 45 francs, 75 cents paid to Joseff Bader as the balance of his surety. Signed Joseff Bader on April 29, 1844 in San Antonio. "Received from Mister Louis Huth, on behalf of Mr. H[enr]i Castro in Paris.
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