1,721,058 research outputs found
Gingival crevicular fluid alkaline phosphatase activity as a non-invasive biomarker of skeletal maturation
Full text linkTo cite this article: Perinetti G, Baccetti T, Contardo L, Di Lenarda R: Gingival crevicular fluid alkaline phosphatase activity as a non-invasive biomarker of skeletal maturation Orthod Craniofac Res 2011; 14 :44–50Perinetti G, Baccetti T, Contardo L, Di Lenarda RTo evaluate the gingival crevicular fluid (GCF) alkaline phosphatase (ALP) activity in growing subjects in relation to the stages of individual skeletal maturation.The Department of Biomedicine, University of Trieste. Seventy-two healthy growing subjects (45 women and 27 men; range, 7.8–17.7 years).Double-blind, prospective, cross-sectional design. Samples of GCF were collected from each subject at the mesial and distal sites of both of the central incisors, in the maxilla and mandible. Skeletal maturation phase was assessed through the cervical vertebral maturation (CVM) method. Enzymatic activity was determined spectrophotometrically.The relationship between GCF ALP activity and CVM stages was significant. In particular, a twofold peak in enzyme activity was seen at the CS3 and CS4 pubertal stages, compared to the pre-pubertal stages (CS1 and CS2) and post-pubertal stages (CS5 and CS6), at both the maxillary and mandibular sites. No differences were seen between the maxillary and mandibular sites, or between the sexes.As an adjunct to standard methods based upon radiographic parameters, the GCF ALP may be a candidate as a non-invasive clinical biomarker for the identification of the pubertal growth spurt in periodontally healthy subjects scheduled for orthodontic treatment.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79300/1/j.1601-6343.2010.01506.x.pd
Effect of RME and headgear treatment on the eruption of palatally displaced canines: a randomized clinical study.
Full text linkObjective: To determine the effectiveness of orthodontic treatment finalized on the maintenance/ improvement the upper arch perimeter to assist in the successful eruption of palatally displaced maxillary canines (PDCs).
Materials and Methods: The randomized prospective design comprised 64 subjects with PDCs who were randomly assigned to one of three groups: cervical pull headgear (HG); rapid maxillary expansion and cervical pull headgear (RME/HG); or untreated control group (CG). Panoramic radiographs and lateral cephalograms were evaluated at the time of initial observation (T1) and after an average period of 18 months (T2). At T2 the success of canine eruption was evaluated. A superimposition study on lateral cephalograms was undertaken to evaluate the T1–T2 changes in the sagittal position of the upper molars in the three groups.
Results: The prevalence of successful eruption was 85.7% in the RME/HG group and 82.3% in the HG group. Both these prevalence rates were significantly greater than the success rate in untreated control subjects (36%). The cephalometric superimposition study showed a significant mesial movement of the upper first molars in the CG compared with the HG and RME/HG groups. Conclusions: The use of rapid maxillary expansion and headgear (or headgear alone) in PDC cases increases the success rate of eruption of the canine significantly (almost three times more than in untreated controls). (Angle Orthod. 2011;81:370–374.
Gingival Crevicular Fluid as a Source of Biomarkers of Patient Responsiveness to Orthodontic Treatment.
No full textFrictional Forces of Conventional versus Self-Ligating Brackets Evaluated by a New in vitro Model System
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Early orthodontic treatment of skeletal open-bite malocclusion: A systematic review
No full textThe aim of this study was a systematic review of the literature to assess the scientific evidence on the actual outcome of early treatments of open-bite malocclusions. A literature survey was done by applying the Medline database (Entrez PubMed). The survey covered the period from January 1966 to July 2004 and used the MeSH, Medical Subject Headings. The following study types that reported data on the treatment effects included: randomized clinical trials (RCT), prospective and retrospective studies with concurrent untreated as well as normal controls, and clinical trials comparing at least two treatment strategies without any untreated or normal control group involved. The search strategy resulted in 1049 articles. After selection according to the inclusionary/exclusionary criteria, seven articles qualified for the final review analysis. No RCTs of early treatment of anterior open bite have been performed. Two controlled clinical trials of early anterior open bite have been performed, and these two studies indicated the effectiveness of treatment in the mixed dentition with headgears or functional appliances (or both). Most of the studies had serious problems of lack of power because of small sample size, bias and confounding variables, lack of method error analysis, blinding in measurements, and deficient or lack of statistical methods. Thus, the quality level of the studies was not sufficient enough to draw any evidence-based conclusions. © 2005 by The EH Angle Education and Research Foundation, Inc
Dentoskeletal changes associated with fixed and removable appliances with a crib in open-bite patients in the mixed dentition
No full textIntroduction: The aim of this study was to compare the effects of the quad-helix/crib (Q-H/C) appliance and a removable plate with a crib (RP/C) in patients with dentoskeletal open bite. Methods: Both samples consisted of 20 subjects. Lateral cephalograms were analyzed before treatment (T1) and after active treatment (T2). The average age at T1 was 8.4 years, and the mean duration of treatment was 1.5 years in both groups. The T2-T1 changes in the 2 groups were compared with a nonparametric test for independent samples (Mann-Whitney U test). Results and Conclusions: Both the Q-H/C and the RP/C appliances induced favorable dental effects. However, a compliance-free appliance, such as the Q-H/C appliance, produced more favorable vertical skeletal changes
Effects of maxillary protraction with or without expansion on the sagittal pharyngeal dimensions in Class III subjects
No full textIntroduction: The aim of this cephalometric study was to analyze the effects of rapid maxillary expansion (RME) and facemask (FM), or FM combined with bite block (BB), on the sagittal pharyngeal dimensions in subjects with Class III malocclusion when compared with an untreated Class III control group. Methods: Thirty-nine subjects (22 girls, 17 boys) were divided into 2 groups: the FM/BB group (22 subjects; mean ages, 8.9 years +/- 1.5 before treatment and 10.5 years +/- 1.3 after treatment) and the RME/FM group (17 subjects; mean ages, 7.1 years +/- 1.8 before treatment and 9.2 years +/- 1.8 after treatment). The treated groups were compared with an untreated Class III control group of 20 subjects (mean ages, 8.1 years +/- 1.2 at the first observation and 10 years +/- 1.7 at the second observation). All subjects were at prepubertal stage of skeletal maturity at both times. Comparisons of these changes between the 3 groups were analyzed with the Kruskal-Wallis 1-way analysis of variance (ANOVA) on ranks with post-hoc tests. Results: The favorable skeletal maxillary and mandibular changes produced by maxillary protraction with or without RME were not associated with significant changes in the sagittal oropharygeal and nasopharyngeal airway dimensions. Conclusions: Orthopedic treatment of Class III malocclusion does not produce a significant increase in airway dimensions in the short term. (Am J Orthod Dentofacial Orthop 2009;135:777-81
IL CANINO SUPERIORE INCLUSO: Diagnosi e Terapia basate sull’evidenza scientifica
No full textLa possibilità di diagnosticare precocemente l’inclusione del canino superiore permanente e l’eventualità
di intercettare la sua malposizione rappresentano per l’ortodontista grandi opportunità; quando queste
condizioni non si realizzano, la programmazione di un caso complesso ortodontico chirurgico mette
alla prova il singolo operatore e la sua abilità clinica.
Per scrivere un testo dedicato interamente ad un argomento così specifico come la malposizione
intraossea dei canini superiori abbiamo impiegato più di tre anni. Il progetto ha avuto inizio quando,
in un particolare momento di tranquillità, ho deciso di raccogliere tutta la nostra esperienza e
tutti i casi da noi trattati sull’argomento per valutare insieme quali fossero il percorso diagnostico
più completo, la scelta terapeutica più idonea e l’approccio ortodontico-chirurgico più efficace.
Non potevamo inoltre trascurare un’analisi completa della letteratura attraverso la quale siamo
riusciti a chiarirci alcuni dubbi, peraltro leciti e sempre presenti quando ci si pone davanti ad un caso
ortodontico con programmazione terapeutica complessa.
La raccolta e la revisione della letteratura è stata curata interamente dalla Dott.ssa Maria Rosaria
Ricchiuti che in questi tre anni ha elaborato la sua Tesi di Specializzazione in Ortognatodonzia sotto
la mia guida. Con costanza e tenacia ha analizzato singolarmente ogni articolo discutendolo con
grande capacità critica e riportandolo fedelmente nel testo.
Con la Dott.ssa Manuela Mucedero abbiamo documentato e condotto la terapia di tutti i casi
pubblicati nel libro. Insieme abbiamo programmato le terapie più complesse e progettato gli ancoraggi
intraorali nei casi ad approccio combinato ortodontico-chirurgico. I suoi suggerimenti nel testo
sono stati preziosi e i risultati evidenti dall’analisi dei casi portati a termine esaltano le sue qualità
cliniche di ortodontista.
Da tempo oramai le Scuole Ortodontiche di Roma “Tor Vergata” e Firenze sono unite in progetti
clinici e di ricerca a breve e a lungo termine. Per tale motivo è stato per me un piacere invitare il
Dott. Tiziano Baccetti a collaborare alla realizzazione di questo libro su un argomento che lo vede
scientificamente coinvolto da molti anni in numerose ricerche a carattere diagnostico e clinico. A lui
è stato affidato il compito di effettuare il controllo e la revisione critica del testo, che attualmente è
senz’altro il più aggiornato sull’argomento, nonché la formulazione di alcune linee guida di diagnosi
e terapia basate sull’evidenza scientifica, che il lettore troverà al termine della trattazione.
In realtà molte altre persone hanno lavorato con noi, anche se non sono state direttamente
coinvolte; tutti i consulenti che collaborano nel Reparto di Ortodonzia da me diretto presso il PTV
(Policlinico Universitario di “Tor Vergata”) e gli specializzandi che effettuano il loro tirocinio pratico
presso il reparto. Solo grazie ad un costante aggiornamento e ad un continuo confronto la nostra
esperienza clinica si è ampliata e fortificata nel tempo fino ad avere il coraggio di realizzare una monografia
su un argomento che rappresenta una vera sfida per l’ortodontista.
Un ringraziamento particolare infine al Dott. Corrado Agrestini, responsabile della gestione chirurgica
di tutti i nostri casi. Spesso ci ritroviamo insieme a discutere sulla scelta terapeutica più idonea;
solo grazie ad una effettiva e costante collaborazione sostenuta da una grande stima reciproca
riusciamo ad ottenere i risultati che vi mostriamo.
Spero che la lettura di questo testo risulti chiara e di facile consultazione, ma soprattutto utile
per tutti coloro che, appassionati alla materia, si avvicinano timorosi ad affrontare situazioni cliniche
complesse come la malposizione intraossea dei canini permanenti superiori. Le indicazioni diagnostico-
terapeutiche supportate da una valida analisi scientifica forniranno elementi preziosi nella gestione
dei casi clinici individuali, a beneficio della salute, funzione, ed estetica oro-facciale dei nostri
pazienti
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